試薬内包カプセルネットワーク ー単結晶の中で高活性試薬をより安全に扱い易くするー
| Project/Area Number |
13J10288
|
|---|
| Research Category |
Grant-in-Aid for JSPS Fellows
|
| Allocation Type | Single-year Grants |
|---|
| Section | 国内 |
|---|
| Research Field |
Functional materials chemistry
|
|---|
| Research Institution | The University of Tokyo |
|---|
Principal Investigator |
寧 國宏 東京大学, 工学系研究科, 特別研究員(PD)
|
|---|
| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
|
| Budget Amount *help |
¥2,070,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥900,000 (Direct Cost: ¥900,000)
|
|---|
| Keywords | sugar sponge / solvent exchange / host-guest chemistry / structural analysis / networked capsules / stable encapsulation / acrylate-esters / discrete capsules |
|---|
| Outline of Annual Research Achievements |
In this year, I have developed a new sugar sponge:
1.Synthesis of sugar sponge: Complexation of NaOH and 1,4-Bis(β-D-mannopyranosyl)benzene furnished sugar sponge with hydrophilic pores where EtOH guest molecules were trapped by multiple hydrogen bonding interactions. Soaking crystals of sugar sponge in diethyl ether or CHCl3 resulted in guest exchange in a single-crystal-to-single-crystal fashion, thus Et2O or CHCl3 in pores were observed by single crystal X-ray analysis
2. Analysis of water soluble guest molecule- propylene oxide: Owing to the confined space and multiple hydrogen bonding sites, the sugar sponge is able to strongly accommodate the water guest molecules, S-propylene oxide. Immersion of one piece of crystals with ~ 100 × 80 × 60 μm size into 10 μL S-propylene oxide guests and stand at 50 oC for one day gives the guest-included sugar sponge. X-ray crystallographic analysis revealed that guest molecules were included within the pores at a ligand-guest ratio of 1:0.8, which was well agreement with the results of proton NMR analysis. It is worthy to note that guest molecules 3 were well arranged though intermolecular hydrogen bonding and fixed their position within the pores via C-H….π interaction and multiple hydrogen bonding with frameworks
|
| Research Progress Status |
26年度が最終年度であるため、記入しない。
|
| Strategy for Future Research Activity |
26年度が最終年度であるため、記入しない。
|
Report
(2 results)
Research Products
(6 results)
