Development of a super-parallel MR microscope for construction of a 3D image database of human embryos
| Project/Area Number |
14350039
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied physics, general
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| Research Institution | University of Tsukuba |
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Principal Investigator |
KOSE Katsumi University of Tsukuba, Institute of Applied Physics, Professor, 物理工学系, 教授 (60186690)
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| Project Period (FY) |
2002 – 2003
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| Project Status |
Completed (Fiscal Year 2003)
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| Budget Amount *help |
¥13,500,000 (Direct Cost: ¥13,500,000)
Fiscal Year 2003: ¥4,900,000 (Direct Cost: ¥4,900,000)
Fiscal Year 2002: ¥8,600,000 (Direct Cost: ¥8,600,000)
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| Keywords | MRI / NMR / MR microscope / Human embryo / embryo / 3D image / Super-parallel / super-conducting magnet / 胚子 / 3D画像 |
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| Research Abstract |
Kyoto University has a large human embryo collection (〜50,000 specimens), which were collected from 1961 to 1974. Because such a collection will never be obtained again, their nondestructive 3Dmeasurements are highly desired. Kyoto and Tsukuba Universities have therefore started a project acquiring 3D MR microscopic images of about 1,200 embryos in two years to create a 3D anatomical database for human embryology. Human embryo specimens were chemically fixed in Bouin's fluid and stored in 10% formalin solution. The embryos were imaged in the formalin to avoid susceptibility effect, with a four-or eight-channel super-parallel MR microscope using a 2.34 T/40 cm superconducting magnet. All of the embryos (about 100 speciments for each stage) were measured using a T_1 weighted 3D SE sequence. The image matrix was 128 x 128 x 256 throughout the whole stages but the voxel size was varied from (40μm)^3 to (150μm)^3. Many anatomical structures were clearly visualized in the 3D images. This result demonstrates usefulness of the anatomical image database in human embryology.
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Report
(3 results)
Research Products
(11 results)
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[Journal Article] Development of a Compact MRI System for Trabecular Bone Volume Fraction Measurements2004
Author(s)
Katsumi Kose, Yoshimasa Matsuda, Takeaki Kurimoto, Seitarou Hashimoto, Yukako Yamazaki, Tomoyuki Haishi, Shin Utsuzawa, Hiroshi Yoshioka, Shigemasu Okada, Masaaki Aoki, Tsuyoshi Tsuzaki
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Journal Title
Magn Reson Med 52
Pages: 440-444
Description
「研究成果報告書概要(欧文)」より
Related Report
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[Journal Article] Super-parallel MR Microscope2003
Author(s)
Yoshimasa Matsuda, Shin Utsuzawa, Takeaki Kurimoto, Tomoyuki Haishi, Yukako Yamazaki, Katsumi Kose, Izumi Anno, Mitsuhiro Marutani
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Journal Title
Magn Reson Med 50
Pages: 183-189
Description
「研究成果報告書概要(欧文)」より
Related Report
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