Development and application of artificial acyltransferase models based on host compounds
| Project/Area Number |
14572025
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Kobe Gakuin University |
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Principal Investigator |
KUNISHIMA Munetaka Kobe Gakuin University, Pharmaceutical Chemistry, Associate Professor, 薬学部, 助教授 (10214975)
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| Project Period (FY) |
2002 – 2004
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| Project Status |
Completed (Fiscal Year 2004)
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| Budget Amount *help |
¥4,000,000 (Direct Cost: ¥4,000,000)
Fiscal Year 2004: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2003: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2002: ¥2,100,000 (Direct Cost: ¥2,100,000)
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| Keywords | Host-Guest / enzyme models / amides / acyltransfer / molecular recognistion / dehydrocondensation / bioorganic chemistry / アシル基転移酵素 / 人工酵素 / 触媒的アミド化 / 超分子化学 / ホスト-ゲスト / 超分子 / ホストーゲスト / シクロデキストリン / クラウンエーテル |
|---|
| Research Abstract |
Following Results are successfully obtained.
1.Development of synthetic technology utilizing for the preparation of functionalized dehydrocondensing agents available in water
2.Cyclotransferase model based on 18-crown-6
3.Development of fatty acids-specific acyl CoA transferase models in micelles.
4.Substrate-specific reactions utilizing liquid-liquid biphasic system as a reaction field
5.Novel immobilizing systems of dehydrocondensing agents, which are useful to utilize enzyme models.
6.Peptide synthesis of unprotected amino acids by use of fluorous solvents
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Report
(4 results)
Research Products
(27 results)
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[Book] フルオラスケミストリー2005
Author(s)
国嶋崇隆
Total Pages
9
Publisher
シーエムシー出版
Description
「研究成果報告書概要(和文)」より
Related Report
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