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Mechanisms and significance of delayed onset muscle soreness

Research Project

Project/Area Number 14580049
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 体育学
Research InstitutionYokohama City University

Principal Investigator

NOSAKA Kazunori  Yokohama City University, Graduate School of Integrated Science, Associate Professor (00175522)

Project Period (FY) 2002 – 2003
Project Status Completed (Fiscal Year 2003)
Budget Amount *help
¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 2003: ¥1,300,000 (Direct Cost: ¥1,300,000)
Fiscal Year 2002: ¥2,200,000 (Direct Cost: ¥2,200,000)
Keywordsmuscle soreness / muscle damage / eccentric exercise / ageing / prophylactic modality / therapeutic modality / analgesic effect / muscle function / 遅発性筋肉痛 / 伸張性運動 / 運動強度 / 伸張性筋活動 / 筋力 / 関節可動域 / 血漿CK活性値 / MRI / 上腕屈筋群
Research Abstract

Exercise consisting of predominantly eccentric (lengthening) muscle actions induces delayed onset muscle soreness (DOMS), especially if the exercise is unfamiliar. It is no doubt that DOMS is one of the symptoms of eccentric exercise-induced muscle damage, however, DOMS does not necessarily indicate muscle damage. This study has clarified that the level of DOMS does not reflect the extent of muscle damage, and the time course of DOMS does not correspond to the time course of changes in other indicators of muscle damage. In this context, it is necessary to separate DOMS from other symptoms of eccentric exercise-induced muscle damage. This is especially important for investigating prophylactic or therapeutic modalities. It may be that some interventions are effective only for alleviating DOMS, but others enhance recovery of muscle function without affecting DOMS. Thus, when a treatment is found to alleviate DOMS without any effects on recovery of muscle function, the treatment is still e … More ffective if DOMS is the main concern. Although many therapeutic modalities have been tested their effects on DOMS, it appears that no single treatment has been shown to be very effective for attenuating DOMS, although some modalities such as massage and exercise have been shown to have some analgesic effects. It is clearly shown in this study together with previous studies that muscles performed eccentric exercise become less susceptible to DOMS for several weeks. It is anecdotally reported that muscle soreness is much more delayed with ageing. However, the present study found that this is not necessarily true. An interesting statement was made by an old subject in the present study, who showed the largest changes in muscle strength, upper arm circumference, and plasma CK activity, that "the muscles were sore, but the pain was like nothing compared to the pain I experienced following an operation a long time ago." This could explain the lower DOMS score of the old group compared to the young. Based on the results obtained from this study and literature review, a booklet entitled "Story of Muscle Soreness" (in Japanese) has been made to let people know more about the facts of DOMS. Less

Report

(3 results)
  • 2003 Annual Research Report   Final Research Report Summary
  • 2002 Annual Research Report
  • Research Products

    (29 results)

All 2005 2004 2003 2002 Other

All Journal Article (25 results) Book (1 results) Publications (3 results)

  • [Journal Article] Attenuation of protective effect against eccentric exercise-induced muscle damage2005

    • Author(s)
      Nosaka,K., Newton,M, Sacco,P.
    • Journal Title

      Canadian Journal of Applied Physiology 30

      Pages: 529-542

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Partial protection against muscle damage by eccentric actions at short muscle lengths2005

    • Author(s)
      Nosaka,K., Newton,M, Sacco,P, Chapman,D., Lavender
    • Journal Title

      Medicine and Science in Sports and Exercise 37

      Pages: 746-753

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Attenuation of protective effect against eccentric exercise-induced muscle damage2005

    • Author(s)
      Nosaka, K., Newton, M., Sacco, P.
    • Journal Title

      Canadian Journal of Applied Physiology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Influence of pre-exercise muscle temperature on responses to eccentric exercise2005

    • Author(s)
      Nosaka, K., Newton, M., Sacco, P., chapman, D., Lavender, A.
    • Journal Title

      Medicine and Science in Sports and Exercise (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Influence of pre-exercise muscle temperature on responses to eccentric exercise2004

    • Author(s)
      Nosaka,K., Sakamoto,K, Newton,M, Sacco,P.
    • Journal Title

      Journal of Athletic Training 39

      Pages: 132-137

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Muscle damage and soreness following repeated bout of consecutive drop jumps2004

    • Author(s)
      Miyama,M., Nosaka,K.
    • Journal Title

      Advances in Exercise and Sports Physiology 10

      Pages: 63-69

    • NAID

      110002706017

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Influence of surface on muscle damage and soreness induced by consecutive drop jumps2004

    • Author(s)
      Miyama,M., Nosaka,K.
    • Journal Title

      Journal of Strength and Conditioning Research 18

      Pages: 206-211

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Changes in inflammatory mediators following eccentric exercise of the elbow flexors2004

    • Author(s)
      Hirose,L., Nosaka,K., Newton,M, Lavender,A., Kano,M., Peake,J., Suzuki,K.
    • Journal Title

      Exercise Immunology Review 10

      Pages: 75-90

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Influence of pre-exercise muscle temperature on responses to eccentric exercise2004

    • Author(s)
      Nosaka, K., Sakamoto, K., Newton, M., Sacco, P.
    • Journal Title

      Journal of Athletic Training 39

      Pages: 132-137

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Muscle damage and soreness following repeated bouts of concecutive drop jumps2004

    • Author(s)
      Miyama, M., Nosaka, K.
    • Journal Title

      Advances in Exercise and Sports Physiology 10

      Pages: 63-69

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Influence of surface on muscle damage and soreness induced by consecutive drop jumps2004

    • Author(s)
      Miyama, M., Nosaka, K.
    • Journal Title

      Journal of Strength and Conditioning Research 18

      Pages: 206-211

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Changes in inflammatory mediators following eccentric exercise of the elbow flexors2004

    • Author(s)
      Hirose, L., Nosaka, K., Newton, M., Lavender, A., Kano, M., Peake, J., Suzuki, K.
    • Journal Title

      Exercise Immunology Review 10

      Pages: 75-90

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Muscle damage in resistance training-Is muscle damage necessary for strength gain and muscle hypertrophy?-2003

    • Author(s)
      Nosaka,K., Lavender,A., Newton,M, Sacco,P.
    • Journal Title

      International Journal of Sport and Health Science 1

      Pages: 1-8

    • NAID

      130000069442

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] 「研究成果報告書概要(和文)」より2003

    • Author(s)
      野坂和則
    • Journal Title

      筋力をデザインする第11章筋損傷と再生(杏林書院)

      Pages: 151-168

    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Muscle damage in resistance training-is muscle damage necessary for strength gain and muscle hypertrophy?-2003

    • Author(s)
      Nosaka, K., Lavender, A., Newton, M., Sacco, P.
    • Journal Title

      International Journal of Sport and Health Science 1

      Pages: 1-8

    • NAID

      130000069442

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Delayed-onset muscle soreness does not reflect the magnitude of eccentric exercise-induced muscle damage2002

    • Author(s)
      Nosaka,K., Newton,M, Sacco,P.
    • Journal Title

      Scandinavian Journal of Medicine and Science in Sports 12

      Pages: 337-346

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Muscle damage and sorensee following endurance exercise of the elbow flexors2002

    • Author(s)
      Nosaka,K., Newton,M, Sacco,P.
    • Journal Title

      Medicine and Science in Sports and Exercise 34

      Pages: 920-927

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Repeated eccentric exercise bouts do not exacerbate muscle damage2002

    • Author(s)
      Nosaka,K., Newton,M.
    • Journal Title

      Journal of Strength and Conditioning Research 16

      Pages: 117-122

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Differences in the magnitude of muscle damage between maximal and submaximal eccentric loading2002

    • Author(s)
      Nosaka,K., Newton,M.
    • Journal Title

      Journal of Strength and Conditioning Research 16

      Pages: 202-208

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] 「研究成果報告書概要(和文)」より2002

    • Author(s)
      野坂和則
    • Journal Title

      筋肉の科学事典(福永哲夫編)10.1「筋肉痛のメカニズム」(朝倉書店)

      Pages: 445-471

    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] 「研究成果報告書概要(和文)」より2002

    • Author(s)
      野坂和則
    • Journal Title

      トレーニングによるからだの適応-スポーツ生理学トピックスー(平野裕一、加賀谷淳子編)第4章伸張性筋活動に伴う筋損傷・遅発性筋肉痛とその回復・適応プロセス(トレーニング科学研究会)

      Pages: 40-53

    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Delayed-onset muscle soreness does not reflect the magnitude of Eccentric exercise-induced muscle damage2002

    • Author(s)
      Nosaka, K., Newton, M., Sacco, P.
    • Journal Title

      Scandinavian Journal of Medicine and Science in Sports 12

      Pages: 337-346

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Muscle damage and soreness following endurance exercise of the elbow flexors2002

    • Author(s)
      Nosaka, K., Newton, S., Sacco, P.
    • Journal Title

      Medicine and Science in Sports and Exercise 34

      Pages: 920-927

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Repeated eccentric exercise bouts do not exacerbate muscle damage and repair2002

    • Author(s)
      Nosaka, K., Newton, M.
    • Journal Title

      Journal of Strength and Conditioning Research 16

      Pages: 117-122

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Journal Article] Differences in the magnitude of muscle damage between maximal and submaximal eccentric loading2002

    • Author(s)
      Nosaka, K., Newton, M.
    • Journal Title

      Journal of Strength and Conditioning Research 16

      Pages: 202-208

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Book] 筋肉痛のはなし2004

    • Author(s)
      野坂和則
    • Total Pages
      20
    • Publisher
      トレーニング科学研究会
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kazunori Nosaka, Mike Newton, Paul Sacco: "Delayed-onset muscle soreness does not reflect the magnitude of eccentric exercise-induced muscle damage"Scandinavian Journal of Medicine & Science in Sports. 12. 337-346 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Kazunori Nosaka, Andrew Lavender, Mike Newton, Paul Sacco: "Muscle damage in Resistance Training -Is muscle damage necessary for strength gain and muscle hyper trophy?"International Journal of Sport and Health Science. 1. 1-8 (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] 野坂和則(分担): "筋の科学事典,第10章 筋とコンディショニング「筋肉痛のメカニズム」"福永哲夫編,朝倉書店. 505 (2002)

    • Related Report
      2002 Annual Research Report

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Published: 2002-04-01   Modified: 2016-04-21  

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