| Project/Area Number |
15209071
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Periodontal dentistry
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| Research Institution | HIROSHIMA UNIVERSITY |
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Principal Investigator |
KURIHRA Hidemi Hiroshima University, Graduate School of Biomedical Sciences, Professor, 大学院・医歯薬学総合研究科, 教授 (40161765)
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| Co-Investigator(Kenkyū-buntansha) |
KAWANAMI Masamitsu Hokkaido University, Graduate School of Dental Medicine, Professor, 大学院・歯学総合研究科, 教授 (10133761)
YAMASAKI Kazuhisa Niigata University, Graduate School of Medical and Dental Sciences, Professor, 大学院・医歯学総合研究科, 教授 (00182478)
NISHIMURA Fusanori Okayama University, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Associate Professor, 大学院・医歯学総合研究科, 助教授 (80208222)
NAGATA Toshihiko Tokushima University, School of Dentistry, Professor, 歯学部, 教授 (10127847)
KAWAGUCHI Hiroyuki Hiroshima University, Graduate School of Biomedical Sciences, Associate Professor, 大学院・医歯薬学総合研究科, 助教授 (10224750)
国松 和司 岩手医科大学, 歯学部, 教授 (20170011)
玉澤 かほる 東北大学, 歯学部附属病院, 講師 (00124602)
新田 浩 東京医科歯科大学, 大学院・医歯学総合研究科, 助手 (70237767)
高橋 潤一 東京歯科大学, 歯学部, 講師 (30287180)
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| Project Period (FY) |
2003 – 2005
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| Project Status |
Completed (Fiscal Year 2005)
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| Budget Amount *help |
¥52,910,000 (Direct Cost: ¥40,700,000、Indirect Cost: ¥12,210,000)
Fiscal Year 2005: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000)
Fiscal Year 2004: ¥14,040,000 (Direct Cost: ¥10,800,000、Indirect Cost: ¥3,240,000)
Fiscal Year 2003: ¥28,600,000 (Direct Cost: ¥22,000,000、Indirect Cost: ¥6,600,000)
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| Keywords | periodontitis / daibetes / systemic disease / atherosclerosis / epidemiology / 歯周炎 / インスリン抵抗性 / 循環器疾患 / 口腔ケア / 全身疾患 |
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| Research Abstract |
The purpose of this research is to identify the relationship between periodontitis and systemic disease such as diabetes, atherosclerosis, et al. in Japanese. We collaborated with 13 university in Japan and progressed this research. As results, we got some new views as follows.
1. Periodontitis is associated with diabetes in Japanese subjects.
2. Periodontitis is also associated with atherosclerosis and other systemic disease in Japanese.
3. Periodontal treatment improve the diabetic condition to healthy one.
4. Examination of the effects of surgery or non-surgery periodontal therapy in diabetic patients.
5. Examination of relationship between paeriodontits and high blood pressure.
6. Periodontal bacteria affect cardiovascular disease.
We got many new views on periodontal medicine in Japanese. Periodontitis is tightly associated with systemic disease such as diabetes, atherosclerosis, low weight birth, and others. It was clear that periodontal treatment improve systemic condition. After treatment of periodontitis, diabetic index was improved.
In the future, we have to continue this research to identify the relationship between periodontitis and sysytemic disease. And we have to develop new therapy of periodontitis on the basis of EBM(evidence based medicine).
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