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Relationships between tooth number and cardiovascular morbidity or total mortality in 8020 study

Research Project

Project/Area Number 15390655
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Social dentistry
Research InstitutionKyushu Dental College

Principal Investigator

TAKATA Yutaka  Kyushu Dental College, Dentistry, Professor, 歯学部, 教授 (40163208)

Co-Investigator(Kenkyū-buntansha) ANSAI Toshihiro  Kyushu Dental College, Dentistry, Associate Professor, 歯学部, 助教授 (80244789)
AWANO Shuji  Kyushu Dental College, Dentistry, Lecturer, 歯学部, 講師 (20301442)
AKIFUSA Sumio  Kyushu Dental College, Dentistry, Adjunct Researcher, 歯学部, 特別研修員 (40295861)
FUKUHARA Masayo  Kyushu Dental College, Dentistry, Adjunct Researcher, 歯学部, 特別研修員 (90360057)
SONOKI Kazuo  Kyushu Dental College, Dentistry, Assistant, 歯学部, 助手 (50316155)
Project Period (FY) 2003 – 2005
Project Status Completed (Fiscal Year 2005)
Budget Amount *help
¥6,900,000 (Direct Cost: ¥6,900,000)
Fiscal Year 2005: ¥2,300,000 (Direct Cost: ¥2,300,000)
Fiscal Year 2004: ¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 2003: ¥2,500,000 (Direct Cost: ¥2,500,000)
Keywordselderly / 8020 / chewing / general condition / mortality / ADL / epidemiology / tooth / 咀嚼機能 / 口腔 / 心血管病 / 死亡 / 8020研究 / 予後
Research Abstract

In 1998, 823 (309 males and 514 females) 80-year-old individuals, each residing in one of three cities, four towns, one village, or one ward in Fukuoka Prefecture, Japan, participated in the present study. 697 of 823 underwent a laboratory blood examination. During the four-year follow-up, 140 individuals (66 males and 74 females) died. Of these, 43 deaths were due to respiratory system including pneumonia, 36 to cancer, and 34 to cardiovascular diseases with strokes.
Four-year total mortality was related significantly with chewing ability (P=0.01). Compared with individuals capable of chewing 5-15 foods, a shorter survival period was found among individuals of chewing only 0-4 foods. Multivariate Cox proportional analysis adjusted with gender and ADL also showed a poor survival in individuals chewing only 0-4 foods than in those chewable all 15 foods.
Next, only 697 subjects (277 males and 420 females) who underwent blood examination at 80-year were analyzed. During 4-year follow-up, 108 individuals (58 males and 50 females) died. Cox analysis with adjustment for not only gender and ADL but also smoking, BMI, BP, and serum concentrations of cholesterol, glucose, and albumin also demonstrated 2.38 times (P=0.03) higher mortality in individual chewable only 0-4 foods than in those chewing all 15 foods. Similarly, in 5.5-year follow study, subjects who were able to chew 0-4 foods had 2.8 times (P=0.005) higher mortality than those capable to chew all 15 foods, using Logistic regression analysis.
Additionally, by logistic regression analysis, functional dependency was 7.532 times more prevalent in individuals capable of chewing 4 foods or fewer, and 3.333 times more prevalent in those chewing 5-9, than in those chewing all 15 items.
Chewing ability may be independently related with survival and functional status in 80-year olds.

Report

(4 results)
  • 2005 Annual Research Report   Final Research Report Summary
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • Research Products

    (32 results)

All 2006 2005 2004 2003 Other

All Journal Article (23 results) Book (2 results) Publications (7 results)

  • [Journal Article] Can presence of carotid artery calcification on panoramic radiographs predict vascular-related risks among old subjects?2006

    • Author(s)
      Tanaka T, et al., Takata Y
    • Journal Title

      Oral Surgery Oral Medicine Oral Pathology Oral Radiology Endodontics (In press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Clinical significance and variation of the advanced calcified stylohyoid complex detected by panoramic radiographs among 80-year-old subjects.2006

    • Author(s)
      Okabe S, et al., Takata Y
    • Journal Title

      Dentomaxillofacial Radiology 35(In press)

    • NAID

      120006735365

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Chewing and quality of life in an 80-year-old population.2006

    • Author(s)
      Takata Y, et al.
    • Journal Title

      Journal of Oral Rehabilitation (In press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Tooth loss associated with abnormal electrocardiographic findings in octogenarians.2005

    • Author(s)
      Takata Y, et al.
    • Journal Title

      Journal of Kyushu Dental Society 59(4)

      Pages: 153-160

    • NAID

      110006420801

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Evaluation of the relationship between peripheral lesions/sclerotic bone and general bone density as a possible gauge of general health among 80-year olds.2005

    • Author(s)
      Ohba T, Takata Y, et al.
    • Journal Title

      Oral Surgery Oral Medicine Oral Pathology Oral Radiology Endodontics 99(3)

      Pages: 353-358

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Relationship of number of remaining teeth to health-related quality of life in community-dwelling elderly.2005

    • Author(s)
      Akifusa S, et al., Takata Y
    • Journal Title

      Gerodontology 22(1)

      Pages: 91-97

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Evaluation of the relationship between peripheral lesions /sclerotic bone and general bone density as a possible gauge of general health among 80-year olds.2005

    • Author(s)
      Ohba T, Takata Y, et al.
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99(3)

      Pages: 353-358

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Relationship of physical fitness to chewing in 80-year-olds.2004

    • Author(s)
      Takata Y, et al.
    • Journal Title

      Oral Diseases 10(1)

      Pages: 44-49

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Relationship between hepatitis virus infection and dental status in an 80-year-old population.2004

    • Author(s)
      Takata Y, et al.
    • Journal Title

      Journal of Disability and Oral Health 5(2)

      Pages: 65-69

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Activities of daily living and chewing ability in an 80-year-old population.2004

    • Author(s)
      Takata Y, et al.
    • Journal Title

      Oral Diseases 10(6)

      Pages: 365-368

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary 2004 Annual Research Report
  • [Journal Article] 健康な体と身体は口腔から-内科医から見た8020運動-80歳福岡県住民における現在歯数・咀嚼能力と全身との関係 : 特に心電図虚血性変化、日常生活活動能力、運動能力との関係2004

    • Author(s)
      高田豊, 他
    • Journal Title

      日歯医学会誌 23

      Pages: 13-18

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Relationship of physical fitness to chewing in 80-year-olds.2004

    • Author(s)
      Takata Y, at al.
    • Journal Title

      Oral Diseases 10(1)

      Pages: 44-49

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Activities of daily living and chewing ability in an 80-year-old population.2004

    • Author(s)
      Takata Y, at al.
    • Journal Title

      Oral Diseases 10(6)

      Pages: 365-368

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Relationship between general condition and present tooth number or chewing ability in 80-year-old habitants in Fukuoka : Relation, in particular, with electrocardiography ischemic change, activity of daily living, and exercise capacity2004

    • Author(s)
      Takata Y, at al.
    • Journal Title

      Journal of the Japanese Association for Dental Science 23

      Pages: 13-18

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Relationship of physical fitness to chewing in 80-year-olds.2004

    • Author(s)
      Takata Y, et al.
    • Journal Title

      Old Diseases 10(1)

      Pages: 44-49

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Relationship between hepatits virus infection and dental status in an 80-year-old population.2004

    • Author(s)
      Takata Y, et al.
    • Journal Title

      Journal of Disability and Oral Health 5(2)

      Pages: 65-69

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Association of QT interval with blood pressure in 80-year-old subjects.2004

    • Author(s)
      Matsumura K, Takata Y, et al.
    • Journal Title

      Hypertension Research 27(6)

      Pages: 387-391

    • NAID

      10013288993

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 健康な体と身体は口腔から-内科医から見た8020運動-80歳福岡県住民における現在歯数・咀嚼能力と全身との関係:特に心電図虚血性変化、日常生活活動能力、運動能力との関係2004

    • Author(s)
      高田豊, 他
    • Journal Title

      日歯医学会誌 23

      Pages: 13-18

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Evaluation of calcified carotid artery atheromas detected by panoramic radiographs among 80-year-olds.2003

    • Author(s)
      Ohba T, Takata Y, et al.
    • Journal Title

      Oral Surgery Oral Medicine Oral Pathology Oral Radiology Endodontology 96(5)

      Pages: 647-650

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Association of the dental status with blood pressure and heart rate in 80-year-old subjects.2003

    • Author(s)
      Matsumura K, et al., Takata Y
    • Journal Title

      Japanese Heart Journal 44(6)

      Pages: 943-951

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Evaluation of calcified carotid artery atheromas detected by panoramic radiographs among 80-year-olds.2003

    • Author(s)
      Ohba T, Takata Y, at al.
    • Journal Title

      Oral Surgery Oral Medicine Oral Pathology Oral Radiology Endodontology 96 (5)

      Pages: 647-650

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Association of the dental status with blood pressure and heart rate in 80-year-old subjects.2003

    • Author(s)
      Matsumura K, at al., Takata Y
    • Journal Title

      Japanese Heart Journal 44(6)

      Pages: 943-951

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Geriatrics.2003

    • Author(s)
      Takata Y
    • Journal Title

      Medicine for Dentistry, second edition revision

      Pages: 333-339

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Book] 高血圧診療のコツと落とし穴2004

    • Author(s)
      高田豊
    • Publisher
      中山書店
    • Related Report
      2004 Annual Research Report
  • [Book] 歯科のための内科学. 改訂第2版2003

    • Author(s)
      高田豊
    • Publisher
      南江堂
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Publications] Takata Y, Kurokawa H, Fukuda J: "Transfusion transmitted virus (TTV) in dental patients."International Journal of Oral and Maxillofacial Surgery. 32. 184-187 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Takata Y, et al.: "Prevalence of hepatitis virus infection in dental patients with impacted teeth or jaw deformities."Oral Surgery Oral Medicine Oral Pathology Oral Radiology Endo dontics. 96(1). 26-31 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Takata Y, et al.: "Relationship of physical fitness to chewing in 80-year-olds."Oral Diseases. 10(1). 44-49 (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] Takata Y, et al.: "Relationship between hepatitis virus infection and dental status in an 80-year-old population."Journal of Disability and Oral Health. in press. (2004)

    • Related Report
      2003 Annual Research Report
  • [Publications] Ohta T, Takata Y, et al.: "Evaluation of calcified carotid artery atheromas detected by panoramic radiographs among 80-year-olds."Oral Surgery Oral Medicine Oral Pathology Oral Radiology Endo dontics. 96(5). 647-650 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Matsumura K, et al., takata Y: "Association of the dental status with blood pressure and heart rate in 80-year-old subjects."Japanese Heart Journal. 44(6). 943-951 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 高田豊: "歯科のための内科学.改訂第2版"南江堂. 333-339 (2003)

    • Related Report
      2003 Annual Research Report

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Published: 2003-04-01   Modified: 2016-04-21  

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