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MEG Analysis of Auditory Response and Clinical Epidemiology on Relationship between Occlusal and Chewing Ability and Hearing

Research Project

Project/Area Number 15390657
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Social dentistry
Research InstitutionTokyo Dental College

Principal Investigator

MATSUKUBO Takashi  TOKYO DENTAL COLLEGE, DEPARTMENT OF EPIDEMIOLOGY AND PUBLIC HEALTH, PROFESSOR, 歯学部, 教授 (90112804)

Co-Investigator(Kenkyū-buntansha) SATO Tooru  TOKYO DENTAL COLLEGE, DEPARTMENT OF CROWN AND BRIDGE, PROFESSOR, 歯学部, 教授 (50192092)
ONOZUKA Minoru  KANAGAWA DENTAL COLLGE, DEPARTMENT OF PHYSIOLOGY, PROFESSOR, 歯学部, 教授 (90084780)
FUJITA Masafumi  UNIVERSITY OF GIFU, DEPARTMENT OF ANATOMY, ASSISTANT PROFESSOR, 大学院・医学研究科, 講師 (50021449)
石川 達也  東京歯科大学, 歯学部, 教授 (30085708)
Project Period (FY) 2003 – 2005
Project Status Completed (Fiscal Year 2005)
Budget Amount *help
¥9,200,000 (Direct Cost: ¥9,200,000)
Fiscal Year 2005: ¥2,900,000 (Direct Cost: ¥2,900,000)
Fiscal Year 2004: ¥2,800,000 (Direct Cost: ¥2,800,000)
Fiscal Year 2003: ¥3,500,000 (Direct Cost: ¥3,500,000)
KeywordsAuditory evoked response / MEG / Occlusion / New device to monitor occlusal pressure / Unilateral chewing / Chewing position / Clinical epidemiology / Audiometer
Research Abstract

The purposes of this study were (1)to examine the mechanism responsible for changes in hearing with the improved occlusal conditions seen in clinical cases, (2)to examine whether there was a relationship between unilateral chewing and hearing level, (3)to examine whether analysis of audiogram plotted by an audiometer could be use to evaluate patient's chewing-sites.
Study : Changes in auditory evoked magnetic fields (AEFs) were analyzed when subjects bite a cotton roll by magnetoencephalography (MEG). All ECDs for the three occlusal conditions localized in less than ±1mm compared with the control group. There were no significant differences in peak latency (ms) for the N100m of the AEF among all occlusal conditions and the control group. The response of AEFs decreased according to the strength of biting pressure in all subjects. The response in the right hemisphere was higher than for the left hemisphere under the experimental conditions. The response was significantly smaller in the ri … More ght hemisphere as biting on the same side.
We need to conduct further studies to confirm the role of : 1)changes in the anatomical structure of the auris media and auris interna due to shifting in the temporomandibular joint (TMJ), 2)innervating neurarchy in the auris media and auris interna, and 3)gate control theory which is the suppression phenomenon in sonic sensation.
Study II-1 : Subjects participated in this study was 262, who visited the dental office in Tokyo. In this clinic, healing levels of the most of patients were measured by audiometer. We used the patient's audiogram before and after dental treatment and chewing instruction. We attempt to classify the patterns of hearing levels at all wavelengths (Hz) and summarized as five groups. Sex and age distribution in each class was analyzed and also comparison of audiogram before and after dental treatment and chewing instructions was performed by paired t-test using SAS software Ver. 8.2.
Data suggest that 1)Unilateral chewing had clearly affected hearing ability, 2)Our classification is useful to make diagnosis chewing site of the patient and also it can be useful to evaluate dental treatments, and 3)Dental treatment have possibility to improve hearing ability of patients.
StudyII-2 : There were 20 subjects (3 females, 17 males, aged 27- 58) who visited a dental clinic. Individual written informed consent to this study was obtained before the experiment, which was approved by the Ethics Committee of the TDC. We conducted a questionnaire, oral examination, occlusal examination with an Occluzer (GC FPD-707), and the Sirognathograph Analyzing System (Tokyo Shika Sangyo). We also made a plaster cast of the subjects' teeth on their first visit. We evaluated each subject's dynamic function with a combination of these five techniques and pattern analysis.
The results revealed that a more detailed evaluation of dynamic occlusal and chewing functions can be undertaken by combining pattern analysis with conventional evaluations. Less

Report

(4 results)
  • 2005 Annual Research Report   Final Research Report Summary
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • Research Products

    (31 results)

All 2006 2005 2004 2003 2002 Other

All Journal Article (22 results) Book (3 results) Publications (6 results)

  • [Journal Article] Sallva-promoted adhesion of streptococcus mutans MT8148 associates with dental plaque and caries susceptibility2006

    • Author(s)
      Shimotoyodome, A., Kobayashi, H., Tokimitsu, I., Matsukubo, T., Takaesu, Y.
    • Journal Title

      Caries Res 40・2(in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Percentlle curve of food acceptance response score in assessing chewing function in adults2006

    • Author(s)
      Sakurai, M., Tada, A., Suzuki, K., Yoshino, K., Sugihara, N., Matsukubo, T.
    • Journal Title

      Bull Tokyo dent Coll 47・2(in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Relationship between number of present teeth and nutritional intake in institutionalized elderly2006

    • Author(s)
      Suzuki, K., Nomura, T., Sakurai, M., Sugihara, N., Yamanaka, S., Matsukubo, T.
    • Journal Title

      Bull Tokyo dert Coll 47・2(in press)

    • NAID

      110005943787

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Statherin and Histatin 1 Reduce Parotid Saliva-Promoted Streptococcus mutans Strain MT8148 Adhesion to Hydroxyapatite Surfaces2006

    • Author(s)
      Shimotoyodome, A., Kobayashi, H., Tokimitsu, I., Matsukubo, T., Takaesu, Y.
    • Journal Title

      Caries Res (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Sucrose Substitutes and Their Role in Caries Prevention2006

    • Author(s)
      Matsukubo, T., Takazoe I., I
    • Journal Title

      Int Dent J. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Percentile Curve of Food Acceptance Response Score in Assessing Chewing Function in Adults2006

    • Author(s)
      Sakurai, M., Tada, A., Suzuki, K., Yoshino, K., Sugihara, N., Matsukubo, T
    • Journal Title

      Bull Tokyo dental Coll 47(in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Relationship between Number of Present Teeth and Nutritional Intake in Institutionalized Elderly2006

    • Author(s)
      Suzuki, K., Nomura, T., Sakurai, M., Sugihara, N., Yamanaka, S., Matsukubo, T.
    • Journal Title

      Bull Tokyo dental Coll 47(in press)

    • NAID

      110005943787

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Saliva-promoted adhesion of Streptococcus mutans MT8148 associates with dental plaque and caries susceptibility2006

    • Author(s)
      Shimotoyodome, A., Kobayashi, H., Tokimitsu, I., Matsukubo, T., Takaesu, Y.
    • Journal Title

      Caries Res 40・2(In press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Percentile curve of food acceptance response score in assessing chewing function in adults2006

    • Author(s)
      Sakural, M., Tada, A., Suzuki, K., Yoshino, K., Sugihara, N., Matsukubo, T.
    • Journal Title

      Bull Tokyo dent Coll 47・2(In press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Relationship between number of present teeth and nutritional intake in institutionalized elderly2006

    • Author(s)
      Suzuki, K., Nomura, T., Sakurai, M., Sugihara, N., Yamanaka, S., Matsukubo, T.
    • Journal Title

      Bull Tokyo dent Coll 47・2(In press)

    • NAID

      110005943787

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 総義歯患者における咬合関連症候群(その1) 咬合機能不全と全身症状との関連調査2005

    • Author(s)
      谷本裕子, 鯉田容子, 中村昭二, 玉川秀泰, 永原邦茂, 松久保隆
    • Journal Title

      日本全身咬合学会誌 11・1

      Pages: 4-8

    • NAID

      10016759932

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Journal Article] Relation of dental visits by japanese elderly to dental characteristics and oral condition2005

    • Author(s)
      Sugihara, N., Maki, Y., Matsukubo, T., Takaesu, Y.
    • Journal Title

      Dentistry Japan 41・1

      Pages: 86-88

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Relation of dental visit by Japanese elderly to dental characteristics and oral condition2005

    • Author(s)
      Sugihara, N, Maki, Y, Matsukubo, T, Takaesu, Y.
    • Journal Title

      Dentistry Japan (Short Communication) 41

      Pages: 86-88

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Relation of dental visits by Japanese elderly to dental characteristics and oral condition2005

    • Author(s)
      Sugihara, N., Maki, Y., Matsukubo, T., Takaesu, Y.
    • Journal Title

      Dentistry Japan 41・1

      Pages: 86-88

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Salivary flow and its relationship to oral signs and symptoms in patients with dry eyes2004

    • Author(s)
      Koseki M, Maki Y, Matsukubo T, Ohashi Y, Tsubota K
    • Journal Title

      Oral Dis. 10

      Pages: 75-80

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Comparison of short-term in vitro fluoride release and recharge from four different types of pit-and fissure sealant2004

    • Author(s)
      Koga, H., Kameyama, A., Matsukubo, T.Hirai, Y., Takaesu, Y.
    • Journal Title

      Bull Tokyo dental Coll. 45

      Pages: 173-179

    • NAID

      110004708210

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The effect of cotton roll biting on auditory evoked magnetic fields, Frontiers in Human Brain Topography2004

    • Author(s)
      Kobayashi Y, Matsukubo T, Sato T, Nagasaka H, Sugihara N, Yumoyo M, Ishikawa T
    • Journal Title

      Proceedings of the 15th World Congress of the International Society for Brain Electromagnetic Topography (ISBET 2004), International Congress Series 1270

      Pages: 324-328

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Salivary flow and its relationship to oral signs and symptoms in patients with dry eyes2004

    • Author(s)
      Koseki M, Maki Y, Matsukubo T, Ohashi Y, Tsubota K.
    • Journal Title

      Oral Dis 10

      Pages: 75-80

    • Related Report
      2004 Annual Research Report
  • [Journal Article] The effect of cotton roll biting on auditory evoked magnetic fields2004

    • Author(s)
      Kobayashi Y, Matsukubo T, Sato T, Nagasaka H, Sugihara N, Yumoto M, Ishikawa T.
    • Journal Title

      Frontiers in Human Brain Topography、Proceedings of the 15th World Congress of the International Society for Brain Electromagnetic Topography (ISBET 2004)、International Congress Series 1270

      Pages: 324-328

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Comparison of short-term in vitro fluoride release and recharge from four different types of pit-and-fissure sealants2004

    • Author(s)
      Koga, H., Kameyama, A., Matsukubo, T., Hirai, Y., Takaesu, Y.
    • Journal Title

      Bull Tokyo dent Coll 45

      Pages: 173-179

    • NAID

      110004708210

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Relationship between oral health behaviors and general health behaviors in a Japanese adult population2003

    • Author(s)
      Tada, A.Matsukubo, T.
    • Journal Title

      J Public Health Dent 63

      Pages: 250-254

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] (2002) : Changes and equaliozation in hearing level induced by dental treatment and instruction in bilaterally equalized chewing : A clinical report2002

    • Author(s)
      Nagasaka, H., Matsukubo, T., Takaesu, Y., Kobayashi, Y., Satou, T., Ishikawa, T.
    • Journal Title

      Bull Tokyo dental Coll 43

      Pages: 243-250

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Book] 唾液による健康づくり-明日からの臨床に取り組む-, PART2 唾液が関わる疾患と臨床対応 8. 唾液で診るう触リスク2005

    • Author(s)
      松久保 隆:著分担
    • Total Pages
      215
    • Publisher
      ヒョーロン
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Book] 口腔保健マニュアル2005

    • Author(s)
      松久保 隆:著分担
    • Total Pages
      177
    • Publisher
      南山堂
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary
  • [Book] 唾液による健康づくり-明日からの臨床に取り組む-,PART2 唾液が関わる疾患と臨床対応 8.唾液で診るう蝕リスク2005

    • Author(s)
      松久保 隆:著分担
    • Total Pages
      215
    • Publisher
      ヒョーロン
    • Related Report
      2005 Annual Research Report
  • [Publications] 長坂斉, 中村昭二, 松久保隆, 永原邦茂, 星詳子, 高江洲義矩, 渡辺誠, 石川達也: "オクルーザルパワーゾーンにかかわる咬合機能と聴力値"日歯医会誌. 56(3). 215-224 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 藤々木英文, 中村昭二, 田中一生, 久馬厚, 星詳子, 永原邦茂, 長坂斉, 渡辺誠, 松久保隆, 石川達也: "咬合と聴力に関する臨床的研究 その2.軽度のTMDをもつ1被験者のオージオメーター測定値(気導聴力)の変動"全身咬合. 9(1). 46-52 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 佐々木琢磨, 中村昭二, 藤々木英文, 鈴木宏和, 永原邦茂, 星詳子, 長坂斉, 渡辺誠, 松久保隆, 石川達也: "咬合と聴力に関する臨床的研究 その3.有歯顎者における噛み癖と気導聴力値"全身咬合. 9(1). 31-38 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 長坂斉, 中村昭二, 青木聡, 永原邦茂, 渡辺誠, 星詳子, 松久保隆, 石川達也: "咬合と聴力に関する臨床的研究 その4.咬合関連聴力低下の偏位咀嚼分類(試案)からみた臨床調査"全身咬合. 9(1). 22-30 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 吉野浩一, 松久保 隆, 高江洲義矩: "コホート調査からみた喫煙量と歯の喪失との関連"口腔衛会誌. 53(2). 98-102 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Tada, A., Matsukubo, T.: "Relationship between oral health behaviors and general health behaviors in a Japanese adult population"J Public Health Dent. 63(4). 250-254 (2003)

    • Related Report
      2003 Annual Research Report

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Published: 2003-04-01   Modified: 2016-04-21  

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