Effect of exercise using eccentric contraction on skeletal muscles in rats
| Project/Area Number |
15500361
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Kyoto University |
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Principal Investigator |
KUROKI Hiroshi Kyoto University, Faculty of Medicine, Associate Professor, 医学部, 助教授 (20170110)
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| Project Period (FY) |
2003 – 2004
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| Project Status |
Completed (Fiscal Year 2004)
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| Budget Amount *help |
¥3,100,000 (Direct Cost: ¥3,100,000)
Fiscal Year 2004: ¥1,200,000 (Direct Cost: ¥1,200,000)
Fiscal Year 2003: ¥1,900,000 (Direct Cost: ¥1,900,000)
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| Keywords | rat / skeletal muscle / eccentric contraction / treadmill / therapeutic exercise |
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| Research Abstract |
In order to examine the effect of eccentric-contraction exercise on skeletal muscle, rats were suspended from their tail for two weeks (group S), followed by they ran on a horizontal treadmill (60 min per day) for five days (group H ; low eccentric-contraction group) or a downhill treadmill (group D ; high eccentric-contraction group) or no running (group C ; control). Cross-section area of the soleus muscle was 1822.5±311.76μm^2 in group H,1731.3±164.06μm^2 in group D,2120.4±554.34μm^2 in group C and 1619.6±297.91μm^2 in group S, respectively. Number of the muscle fiber for cross-section area of 0.24 m^2 was 83.5±8.23 in group H,73.8±9.91 in group D,73.0±17.05 in group C and 84.3±10.50 in group S, respectively. No significant difference was observed in the cross-section area and number of the muscle fiber in each group. Number of peripheral nucleus in the muscle was 1.8±0.26 in group H,1.8±0.30 in group D,2.5±0.28 in group C and 1.7±0.29 in group S, respectively. The number significantly increased in the group C (p<0.05). These results suggested that recovery of the muscle might be delayed in both of low and high eccentric-contraction exercise groups.
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Report
(3 results)
Research Products
(2 results)
