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Development of Effective Analytical System for Studies on Human Exposure to Toxic Elements Caused by Environmental Pollution

Research Project

Project/Area Number 15510029
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Environmental impact assessment/Environmental policy
Research InstitutionIwate Medical University

Principal Investigator

SERA Koichiro  Cyclotron Research Center, Iwate Med. Univ., Professor, 医学部, 教授 (00230855)

Co-Investigator(Kenkyū-buntansha) 二ッ川 章二  日本アイソトープ協会, 滝沢研究所, 部長
CHIBA Keiko  Iwate Prefecture University, Associate Professor, 盛岡短期大学部, 助教授 (90197137)
Project Period (FY) 2003 – 2004
Project Status Completed (Fiscal Year 2004)
Budget Amount *help
¥1,600,000 (Direct Cost: ¥1,600,000)
Fiscal Year 2004: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 2003: ¥900,000 (Direct Cost: ¥900,000)
KeywordsPIXE / Toxic elements / Human exposure / Effective Analysis / Quantitative analysis / Environmental pollution / Hair / Nail / 爪の分析 / 試料調製法 / 高効率分析システム / 三検出器同時分析システム / フッ素の定量分析 / 広域的環境汚染
Research Abstract

In 2003 fiscal year, a standard-free method for untreated nail samples was established, and it has been applied to studies on human exposure to mercury and arsenic in various countries such as Philippines and Mongolia. Further, we developed a method of quantitative analysis of fluorine making use of the "Three-detector measuring system" which we established two years ago. This method allows us to discuss correlation between fluorine and other toxic elements such as arsenic and manganese. This method has been applied to the samples taken from Chinese people living in contaminated areas, and the correlation among fluorine, manganese and arsenic were confirmed. This method has been further applied to plants, sea foods, fungi, and tap waters, and becomes a powerful method in the fields of environmental science and sitology etc.
In 2004 fiscal year, a new external multi-channel analyzer was purchased and the system for effective analyses of spectrum data from three detectors was established. It has been applied to more than 2000 hairs, urines and nails taken from people living in contaminated areas in China, Monogolia and Kazakhstan etc. Furthermore, Standard-free methods for spinal fluid, saliva, sweat, tear and snivel have been developed and it made it possible to quantitatively analyze extremely small amount of these samples. We are planning to apply these methods to studies on human exposure to toxic elements in many countries in Asia.

Report

(3 results)
  • 2004 Annual Research Report   Final Research Report Summary
  • 2003 Annual Research Report
  • Research Products

    (26 results)

All 2004 2003 Other

All Journal Article (20 results) Publications (6 results)

  • [Journal Article] Element Concentrations in Hair of Children Living in the Environmentally Degradated District of the East Aral Sea Region.2004

    • Author(s)
      Chiba M, Sera K et al.
    • Journal Title

      Journal of Radioanalytical and Nuclear Chemistry (JRNC) 259-1

      Pages: 149-152

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Finding of High Level Arsenic for Mongolian Villagers' Hair.2004

    • Author(s)
      Murao S, Tumenbayar B, Sera K
    • Journal Title

      International Journal of PIXE 14-3(in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 仁科記念サイクロトロンセンターにおける医療用小型サイクロトロンの応用 -問題解決型・生活密着型研究における小型加速器の役割-2004

    • Author(s)
      世良 耕一郎
    • Journal Title

      加速器 1-3

      Pages: 277-282

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] PIXE(イオン励起X線分光元素分析法)が持つ医学・生物学、環境科学研究ツールとしての可能性2004

    • Author(s)
      世良 耕一郎
    • Journal Title

      岩手医学会誌 56-5

      Pages: 381-387

    • NAID

      110001038739

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] Element Concentrations in Hair of Children Living in the Environmentally Degradated District of the East Aral Sea Region.2004

    • Author(s)
      Chiba M, Sera K et al.
    • Journal Title

      Journal of Radioanalytical and Nuclear Chemistry(JRNC) 259-1

      Pages: 149-152

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Finding of High Level Arsenic for Mongolian Villager's Hair.2004

    • Author(s)
      Murao S, Tumenbayar B, Sera K
    • Journal Title

      International Journal of PIXE 14-3(in press)

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 仁科記念サイクロトロンセンターにおける医療用小型サイクロトロンの応用-問題解決型・生活密着型研究における小型加速器の役割-2004

    • Author(s)
      世良 耕一郎
    • Journal Title

      加速器 1-3

      Pages: 277-282

    • Related Report
      2004 Annual Research Report
  • [Journal Article] A Three-detector Measuring System Using a Pure-Ge Detector2003

    • Author(s)
      Sera K, Terasaki K et al.
    • Journal Title

      International Journal of PIXE 13-1,2

      Pages: 23-35

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Original Method of Quantitative Analysis Developed for Diverse Samples in Various Research Fields. -Quantitative Analysis at NMCC-2003

    • Author(s)
      Sera K
    • Journal Title

      International Journal of PIXE 13-1,2

      Pages: 11-16

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] A Three-detector Measuring System Using a Pure-Ge Detector2003

    • Author(s)
      Sera K, Terasaki K et al.
    • Journal Title

      International Journal PIXE 13-1,2

      Pages: 23-35

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Three-detector Measuring System Using a Pure-Ge Detector

    • Author(s)
      Sera, K., Terasaki, K., Murao, S., Futatsugawa, S., Saito, Y.A
    • Journal Title

      Int'l J PIXE Vol.13-1,2

      Pages: 23-35

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Original Method of Quantitative Analysis Developed for Diverse Samples in Various Research Fields. - Quantitative Analysis at NMCC-

    • Author(s)
      Sera, K.
    • Journal Title

      Int'l J PIXE Vol.13-1,2

      Pages: 11-16

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] PIXE Quantitative Analysis at NMCC.

    • Author(s)
      Futatsugawa, S., Saitoh, Y., Hatakeyama, S., Sera, K.
    • Journal Title

      Int'l J PIXE Vol.13-1,2

      Pages: 45-50

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Characterization of Atomaspheric Total Suspended Particulate (TSP) in a Midsize City in Northern Japan. : Non-Snow-Clad Period to Snow-Clad Period Comparison.

    • Author(s)
      Saitoh, K., Iwata, Y., Sera, K., Hirano, K.
    • Journal Title

      Int'l PIXE Vol.13-1,2

      Pages: 51-64

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Multi-site Aerosol Monitoring Using Mini Step Sampler.

    • Author(s)
      Matsuyama, S., Katoh, K., Sugihara, S., Ishii, K., Yamazaki, H., Satoh, T., Amartaivan, Ts., Tanaka, A., Komori, H., Hotta, K., Izukawa, D., Mizuma, K., Orihara, H., Hakamura, E., Satoh, N., Futatugawa, S., Sera, K.
    • Journal Title

      Int'l J PIXE Vol.13-1,2

      Pages: 65-80

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Transport Course of Insoluble and Soluble Substances of Fog Water in Akita Prefecture in Northern Japan.

    • Author(s)
      Kikuchi, R., Intume, J., Yoshimura, K., Kajikawa, M., Ogawa, N., Sera, K., Ozeki, T.
    • Journal Title

      Int'l J PIXE Vol.13-1,2

      Pages: 81-87

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Element Concentrations in Hair of Children Living in the Environmentally Degradated District of the East Aral Sea Region.

    • Author(s)
      Chiba, M., Sera, K., Hashizume, M., Shimoda, T., Sasaki, S., Kunii, O., Inaba, Y.
    • Journal Title

      Journal of Radioanalytical and Nuclear Chemistry (JRNC) 259-1

      Pages: 149-152

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Metod of Quantitative Analysis of Fluorine in Environmental Samples Using a Pure-Ge Detector.

    • Author(s)
      Sera, K., Terasaki, K., Saito, Y., Saitoh, Y., Itoh, J., Futatsugawa, S., Murao, S., Sakurai, S.
    • Journal Title

      Int'1 J PIXE Vol.14-1,2

      Pages: 9-18

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Finding of High Level Arsenic for Monogolian Villagers' Hair.

    • Author(s)
      Murao, S., Tumenbayar, B., Sera, K., Futatsugawa, S., Waza, T.
    • Journal Title

      Int'1 J PIXE Vol.14-3,4

      Pages: 125-131

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Standard-free Method for Body Fluid Samples such as Saliva, Sweat, Snivel and Tear.

    • Author(s)
      Sera, K., Terasaki, K., Itoh, J., Saitoh, Y., Futatsugawa, S., Miura, Y.
    • Journal Title

      Int'1 Journal of PIXE Vol.15-1,2(in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Publications] Murao, S., Sera, K., Futatsugawa, S., Chen, B., Sun, X: "Trace Element Concentration of Leaf and Ash from a Waste Pond at Fankou Mine, China."Int'l Journal of PIXE. 12・1,2. 53-60 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] Murao, S., Futatsugawa, S., Sera, K., Maglambayan, V.B.: "Trace Element Analysis of Tailings from an Indigenous Mining Community, Benguet, Philippines."Int'l Journal of PIXE. 12・1,2. 61-69 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] Habib, M., A., Miono, S., Sera, K., Futatsugawa, S.: "PIXE Analysis of Hair in Arsenic Pollution, Bangladesh."Int'l Journal of PIXE. 12・1,2. 19-34 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] Sera, K., Futatsugawa, S., Miura, Murao, S., Clemente, E.: "Quantitative Analysis of Untreated Human Nails for Monitoring Human Exposure to Heavy Metals."Int'l Journal of PIXE. 12・3,4. 125-136 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] Futatsugawa, S., Sera, K.et al.: "Analysis of Liquid Waste Using PIXE."Int'l Journal of PIXE. 12・3,4. 85-91 (2002)

    • Related Report
      2003 Annual Research Report
  • [Publications] Sera, K., Terasaki, K., Murao, S., Futatsugawa, S., Saitoh, Y.: "A Three-detector Measuring System Using a Pure-Ge Detector"Int'l Journal of PIXE. 13・1,2. 23-35 (2003)

    • Related Report
      2003 Annual Research Report

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Published: 2003-04-01   Modified: 2016-04-21  

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