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Control of Circadian Rhythms Based on The Oscillator Model.

Research Project

Project/Area Number 15560372
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Control engineering
Research InstitutionTohoku University

Principal Investigator

NAKAO Mitsuyuki  Tohoku University, Graduate School of Information Sciences, Professor, 大学院・情報科学研究科, 教授 (20172265)

Co-Investigator(Kenkyū-buntansha) KATAYAMA Norihiro  Tohoku University, Graduate School of Information Sciences, Associate Professor, 大学院・情報科学研究科, 助教授 (20282030)
KARASHIMA Akihiro  Tohoku University, Graduate School of Information Sciences, Research Associate, 大学院・情報科学研究科, 助手 (40374988)
山本 光璋  東北大学, 大学院・情報科学研究所, 教授 (40004618)
Project Period (FY) 2003 – 2004
Project Status Completed (Fiscal Year 2004)
Budget Amount *help
¥3,100,000 (Direct Cost: ¥3,100,000)
Fiscal Year 2004: ¥1,300,000 (Direct Cost: ¥1,300,000)
Fiscal Year 2003: ¥1,800,000 (Direct Cost: ¥1,800,000)
Keywordstime zone flight / reentrainment / phase oscillator model / jet lag / alertness / shiftwork / the suprachiasmatic nucleus / sleep-waking rhythm / 明暗サイクル / 休息-活動サイクル / 運動効果 / 分離再同調
Research Abstract

In this research, we planned to propose the strategy for minimizing the adaptation failure to the shiftwork and time zone flights by controlling the entrainment mechanisms of biological rhythms. The results are summarized as follows. (1)The model of the human circadian clock mechanisms was constructed, which consists of the oscillators I, II, and SW. In addition, the photo-responsiveness was introduced to the model (2)The behavior of biological rhythms under the time-zone flights was simulated by the model The simulations showed the plausible mechanisms underlying the diverse reentrainment patterns such as the orthodrimic, antidromic, and those by partition. That is, the magnitude of photic phase response and its sign when the subject is exposed to light, and the value of the interaction function from the oscillator I to II just after the exposure to light were shown to determine the reentrainment direction. (3)Exercise during waking time in the destination could prevent the circadian … More pacemakers from its reentrainment by partition In addition to the conditions (2), the value of the interaction function from the oscillator SW to II just after the exposure to light modifies the reentrainment direction. According to these knowledge, the favorable flight schedule from Tokyo to New York was proposed to accelerate the reentrainments and reduce the expected jet lag. (4)The phase oscillator does not have the amplitude. On the other hand, the thermoregulatory model of sleep control which we previously proposed has a merit to predict the behavior of alertness under the various circumstances. However, the model application was confined to the steady state where the phase relation between the pacemakers is not expected to significantly change. In other words, it is not applicable to the environments where light-dark and sleep-waking cycles dynamically change. Here, the integrated model was constructed by combining the phase oscillator model and the thermoregulatory model of sleep control This was realized by mapping the phases of the oscillators I and II to those of the oscillators X and Y. This integrated model provides the framework for predicting the behavior of alertness and biological rhythms under the diverse light-dark cycles and working schedules. Less

Report

(3 results)
  • 2004 Annual Research Report   Final Research Report Summary
  • 2003 Annual Research Report
  • Research Products

    (128 results)

All 2004 2003 Other

All Journal Article (99 results) Book (4 results) Publications (25 results)

  • [Journal Article] Is state-dependent alternation of slow dynamics in central single neurons during sleep present in the rat ventroposterior thalamic nucleus?2004

    • Author(s)
      M.Yamamoto et al.
    • Journal Title

      Neuroscience Research 48

      Pages: 203-210

    • NAID

      10014233191

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Modeling interactions between photic and nonphotic entrainment mechanism in transmeridian flights2004

    • Author(s)
      Nakao, Katayama, others
    • Journal Title

      Biological Cybernetics 91

      Pages: 138-147

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Theta wave amplitude and frequency are differently correlated with pontine wave and rapid eye movements during REM sleep in rats.2004

    • Author(s)
      Nakao, Katayama, Karashima, others
    • Journal Title

      Neuroscience Research 50

      Pages: 283-289

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Sleep EEG dynamics in rat barrel cortex associated with sensory deprivation2004

    • Author(s)
      Nakao, Katayama, Karashima, others
    • Journal Title

      NeuroReport 15

      Pages: 2681-2684

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] カルバコールにより賦活される海馬神経回路の時空間ダイナミクス2004

    • Author(s)
      中尾, 片山, 辛島他
    • Journal Title

      生体医工学 42

      Pages: 269-276

    • NAID

      110004014781

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] Noise-induced metastability in the Hodgkin-Huxley neural network2004

    • Author(s)
      Nakao, Katayama, others
    • Journal Title

      Proc.NOLTA 2004

      Pages: 505-508

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] Modeling of the suprachiasmatic nucleus based on reduced molecular clock mechanisms2004

    • Author(s)
      Nakao, Katayama, others
    • Journal Title

      Proc.26th Intl Conf.IEEE EMBS

      Pages: 2897-2900

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] 生体医工学における研究の最前線2004

    • Author(s)
      中尾他
    • Journal Title

      電子情報通信学会情報・システムソサイエティ誌 9

      Pages: 4-11

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] 概日リズムの統合的モデリングに向けて2004

    • Author(s)
      中尾
    • Journal Title

      第81回日本生理学会シンポジウム「分子から固体機能への統合:概日リズムの形成メカニズム」

      Pages: 23-23

    • NAID

      130005447355

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Metastable dynamics of the Hodgkin-Huxley neural network driven by noise2004

    • Author(s)
      Nakao, Katayama, others
    • Journal Title

      Proc.1st Intl.Workshop Biol.Inspired Computing BIC2004

      Pages: 126-129

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] Accelerations of hippocampal theta wave associated with pontine wave occurrence during REM sleep in rats2004

    • Author(s)
      Nakao, Katayama, Karashima, others
    • Journal Title

      Abstracts of Annual Meeting of Society for Neuroscience

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] ブラインド信号分離による胎児心電図の解析2004

    • Author(s)
      中尾, 片山他
    • Journal Title

      電子情報通信学会技術研究報告 MBE2004-63

      Pages: 45-48

    • NAID

      110003288112

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] 睡眠ステージ移行期の脳波ダイナミクスと神経活動の関係2004

    • Author(s)
      中尾, 片山, 辛島他
    • Journal Title

      電子情報通信学会技術研究報告 MBE2004-54

      Pages: 9-12

    • NAID

      110003288103

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] 生体神経回路モデルのネットワーク構造とダイナミクスの関係2004

    • Author(s)
      中尾, 片山他
    • Journal Title

      電子情報通信学会技術研究報告 MBE2004-53

      Pages: 5-8

    • NAID

      110003288102

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] 2プロセスモデルと位相振動子モデルの形式的類似性について2004

    • Author(s)
      中尾
    • Journal Title

      第11回時間生物学会抄録集

      Pages: 144-144

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] 縮約された分子時計機構モデルを用いた視交差上核ダイナミクスのシミュレーション2004

    • Author(s)
      中尾, 片山他
    • Journal Title

      第11回時間生物学会抄録集

      Pages: 145-145

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] 海馬スライスにおける多点局所刺激に伴う発火パターンの変化2004

    • Author(s)
      中尾, 片山他
    • Journal Title

      第19回生体・生理工学シンポジウム論文集

      Pages: 41-42

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] 睡眠-覚醒リズムにおけるステージ移行期の脳波解析2004

    • Author(s)
      中尾, 片山, 辛島他
    • Journal Title

      日本睡眠学会第28回定期学術集会プログラム・抄録集

      Pages: 214-214

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] ラットPGO波に伴う海馬θ波の加速現象2004

    • Author(s)
      中尾, 片山, 辛島他
    • Journal Title

      日本睡眠学会第28回定期学術集会プログラム・抄録集

      Pages: 246-246

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] 成熟ラットの感覚毛除去によるバレル野の睡眠時脳波ダイナミクスの変化2004

    • Author(s)
      中尾, 片山, 辛島他
    • Journal Title

      日本睡眠学会第28回定期学術集会プログラム・抄録集

      Pages: 248-248

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] 海馬切片においてカルバコール負荷により誘発されるθ波様脳波とニューロン活動2004

    • Author(s)
      中尾, 片山, 辛島他
    • Journal Title

      日本睡眠学会第28回定期学術集会プログラム・抄録集

      Pages: 250-250

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Journal Article] Changes of sleep EEG dynamics in rat barrel cortex associated with long-term sensory deprivation2004

    • Author(s)
      Nakao, Katayama, Karashima, others
    • Journal Title

      Neuroscience Research (Supplement) 50

    • NAID

      110003286577

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Instantaneous acceleration of hippocampal theta wave associated with pontine phasic activity during REM sleep in rats.2004

    • Author(s)
      Nakao, Katayama, Karashima, others
    • Journal Title

      Neuroscience Research (Supplement) 50

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 「研究成果報告書概要(和文)」より2004

    • Author(s)
      Nakao, Katayama, others
    • Journal Title

      Neuroscience Research (Supplement) 50

    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Modeling interactions between photic and nonphotic entrainment mechanims in transmeridian flights.2004

    • Author(s)
      M.Nakao, N.Katayama et al.
    • Journal Title

      Biological Cybernetics 91

      Pages: 138-147

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Theta wave amplitude and freqeuncy are differently correlated with pontine wave and rapid eye movements during REM sleep in rats.2004

    • Author(s)
      M.Nakao, A.Karashima, N.Katayama et al.
    • Journal Title

      Neuroscience Research 50

      Pages: 283-289

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Sleep EEG dynamics in rat barrel cortex associated with sensory deprivation.2004

    • Author(s)
      M.Nakao, A.Karashima, N.Katayama et al.
    • Journal Title

      Neuro Report 15

      Pages: 2681-2684

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Spatio-temporal dynamics of calbachol-induced rhythmic neural activities in the hippocampus in vitro.2004

    • Author(s)
      M.Nakao, A.Karashima, N.Katayama et al.
    • Journal Title

      Trans.JSMBE 42

      Pages: 269-276

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Noise-induced metastability in the Hodgkin-Huxley neural network.2004

    • Author(s)
      M.Nakao, N.Katayama et al.
    • Journal Title

      Proc.NOLTA

      Pages: 505-508

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Modeling of the suprachiasmatic nucleus based on reducedmolecular clock mechanisms2004

    • Author(s)
      M.Nakao, N.Katayama et al.
    • Journal Title

      Proc.26th Intl Conf.IEEE EMBS

      Pages: 2897-2900

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Frontiers of biomedical engineering.2004

    • Author(s)
      M.Nakao et al.
    • Journal Title

      Trans Information and Systems Society, IEICE 9

      Pages: 4-11

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Toward an integrated model of circadian rhythms.2004

    • Author(s)
      M.Nakao
    • Journal Title

      Abstracts 81^<st> PSJ Ann meeting 23

    • NAID

      130005447355

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Metastable dynamics of the Hodgkin-Huxley neural network driven by noise.2004

    • Author(s)
      M.Nakao, N.Katayama et al.
    • Journal Title

      Proc.1st Intl.Workshop Biol.Inspired Computing BIC2004

      Pages: 126-129

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Accelerations of hippocampal theta wave associated with pontine wave occurrence during REM sleep in rats.2004

    • Author(s)
      M.Nakao, A.Karashima, N.Katayama et al.
    • Journal Title

      Abstracts of Annual Meeting of Society for Neuroscience 77.12

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] An analysis of fetal ECG by the blind source separation.2004

    • Author(s)
      M.Nakao, N.Katayama et al.
    • Journal Title

      IEICE Technical Report MBE2004-63

      Pages: 45-48

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] A relationship between EG dynamics and neuronal activities across the state-transitions.2004

    • Author(s)
      M.Nakao, A.Karashima, N.Katayama et al.
    • Journal Title

      IEICE Technical Report MBE2004-54

      Pages: 9-12

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Relationship between the structure and the dynamics of biological neural networks.2004

    • Author(s)
      M.Nakao, N.Katayama et al.
    • Journal Title

      IEICE Technical Report MBE2004-53

      Pages: 5-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Formal similarity between the two process model and phase oscillator model.2004

    • Author(s)
      M.Nakao
    • Journal Title

      Abstracts of 11^<th> JSC Ann Meeting 144

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Simulations of the suprachiasmatic nucleus by using the reduced model of molecular clock mechanisms.2004

    • Author(s)
      M.Nakao, N.Katayama et al.
    • Journal Title

      Abstracts of 11^<th> JSC Ann Meeting 145

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Changes of neural activity patterns associated with multiple localized stimuli in the hippocampal slice.2004

    • Author(s)
      M.Nakao, N.Katayama et al.
    • Journal Title

      Proc.19^<th> BPES

      Pages: 41-42

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] EEG analysis across the sleep-waking state-transitions.2004

    • Author(s)
      M.Nakao, A.Karashima, N.Katayama et al.
    • Journal Title

      Abstracts 28^<th> Ann Meeting JSSR 214

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Acceleration of hippocampal theta wave coincided with rat's PGO wave.2004

    • Author(s)
      M.Nakao, A.Karashima, N.Katayama et al.
    • Journal Title

      Abstracts 28^<th> Ann Meeting JSSR 246

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Dynamics change in EEG activity in the rat's barrel cortex with the whiskers clipped.2004

    • Author(s)
      M.Nakao, A.Karashima, N.Katayama et al.
    • Journal Title

      Abstracts 28^<th> Ann Meeting JSSR 248

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Calbachol-induced theta-like EEG activity and neuronal activities in the hippocampal slice.2004

    • Author(s)
      M.Nakao, A.Karashima, N.Katayama et al.
    • Journal Title

      Abstracts 28^<th> Ann Meeting JSSR 250

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Changes of sleep EEG dynamics in rat barrel cortex associated with long-term sensory deprivation.2004

    • Author(s)
      M.Nakao, A.Karashima, N.Katayama et al.
    • Journal Title

      Neuroscience Research (Supplement) 50

    • NAID

      110003286577

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Instantaneous acceleration of hippocampal theta wave associated with pontine phasic activity during REM sleep in rats.2004

    • Author(s)
      M.Nakao, A.Karashima, N.Katayama et al.
    • Journal Title

      Neuroscience Research (Supplement) 50

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Neuronal dynamics activated by local glutamate application in CA3 region of hippocampal slices.2004

    • Author(s)
      M.Nakao, A.Karashima, N.Katayama et al.
    • Journal Title

      Neuroscience Research (Supplement) 50

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Modeling interactions between photic and nonphotic entrainment mechanisms in transmeridian flights2004

    • Author(s)
      Nakao, Katayama, others
    • Journal Title

      Biological Cybernetics 91

      Pages: 138-147

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Theta wave amplitude and freqeuncy are differently correlated with pontine wave and rapid eye movements during REM sleep in rats2004

    • Author(s)
      Nakao, Katayama, Karashima, others
    • Journal Title

      Neuroscience Research 50

      Pages: 283-289

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Sleep EEG dynamics in rat barrel cortex associated with sensory deprivation2004

    • Author(s)
      Nakao, Katayama, Krashima, others
    • Journal Title

      NeuroReport 15

      Pages: 2681-2684

    • Related Report
      2004 Annual Research Report
  • [Journal Article] 概日リズムの統合的モデリングに向けて2004

    • Author(s)
      中尾
    • Journal Title

      第81回日本生理学会シンポジウム「分子から個体機能への統合:概日リズムの形成メカニズム」

      Pages: 23-23

    • NAID

      130005447355

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Changes of sleep EEG dynamics in rat barrel cortex associated with long-term sensory deprivation2004

    • Author(s)
      Nakao, Katayama, Karashima, others
    • Journal Title

      Neuroscience Research(Supplement) 50

    • NAID

      110003286577

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Instantaneous acceleration of hippocampal theta wave associated with pontine phasic activity during REM sleep in rats.2004

    • Author(s)
      Nakao, Katayama, Karashima, others
    • Journal Title

      Neuroscience Research(Supplement) 50

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Neuronal dynamics activated by local glutamate application in CA3 region of hippocampal slices2004

    • Author(s)
      Nakao, Katayama, others
    • Journal Title

      Neuroscience Research(Supplement) 50

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Period and phase adjustments of human circadian rhythms in the real world.2003

    • Author(s)
      M.Nakao et al.
    • Journal Title

      J.Biol.Rhythms 18・3

      Pages: 261-270

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Modeling feedbacks from behavior to pacemakers in non-photic entrainment of human circadian system.2003

    • Author(s)
      M.Nakao
    • Journal Title

      Circadian Clocks as Multi-oscillation System. (K.Honma, S.Honma eds)(Hokkaido University Press, Sapporo) 2003

      Pages: 219-231

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] State-dependent alternation of neuronal slow dynamics in the rat ventroposterior thalamic area.2003

    • Author(s)
      M.Yamamoto et al.
    • Journal Title

      Sleep and Biological Rhythms 1・2

      Pages: 101-103

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] A facial topographic profile of rapid eye movements anticipatory phasic potentials.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Sleep and Biological Rhythms 1・2

      Pages: 151-152

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Changes in the dynamics of sleep electroencephalogram in rat barrel cortex associated with long-term sensory deprivation.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Sleep and Biological Rhythms 1・2

      Pages: 155-157

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] A real-time rapid eye movement sleep analyzer equipped with a portable wide-band polygraphic recorder.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Sleep and Biological Rhythms 1・2

      Pages: 175-177

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Characterization of baroreflex response under head-up tilting.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Proc.25^<th> Ann Int'l Conf IEEE EMBS

      Pages: 256-259

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Temporal relationship between hippocampal theta wave and spontaneous and elicited PGO-like wave during REM sleep in rats.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Neuroscience Research 46・Suppl 1

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Fluctuational dynamics of a neural network model consisting of Hodgkin-Huxley type neurons driven by noise.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Neuroscience Research 46・Suppl 1

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Potine phasic activity is phase-locked to hippocampal theta wave during REM sleep in rats.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Proc.17^<th> Ann.Meeting Ass.Prof.Sleep Soc.

      Pages: 3-3

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Do the processor neurons in the rat brain show the 1/f noise like dynamics during paradoxical sleep.2003

    • Author(s)
      M.Yamamoto et al.
    • Journal Title

      Proc.17^<th> Ann.Meeting Ass.Prof.Sleep Soc.

      Pages: 28-28

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Non-monotonic changes of sleep EEG dynamics in rat barrel cortex associated with long-term sensory deprivation.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Proc.17^<th> Ann.Meeting Ass.Prof.Sleep Soc.

      Pages: 30-30

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Formal similarity between the two process model and a coupled oscillator model.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Proc.17^<th> Ann.Meeting Ass.Prof.Sleep Soc.

      Pages: 98-99

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Modeling of interactions between photic and non-photic entrainment mechanisms in time zone flights.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Abstracts 1^<st> World Congress Chronobiology

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Stability of rhythm trajectory generated by feedback loop models.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Abstracts 1^<st> World Congress Chronobiology

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 逆説睡眠時に観測されるラットP波頻度と海馬θ波周波数との時間関係2003

    • Author(s)
      中尾, 片山, 山本他
    • Journal Title

      日本睡眠学会第28回定期学術集会抄録集

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 分子時計機構のダイナミクス2003

    • Author(s)
      中尾, 片山, 山本他
    • Journal Title

      日本睡眠学会第28回定期学術集会抄録集

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 感覚遮断によるバレル野脳波の統計的性質の長期的変化2003

    • Author(s)
      中尾, 片山, 山本他
    • Journal Title

      日本睡眠学会第28回定期学術集会抄録集

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 睡眠時及び覚醒時の眼球運動に先行するスパイク電位の眼球運動依存性2003

    • Author(s)
      中尾, 片山, 山本他
    • Journal Title

      日本睡眠学会第28回定期学術集会抄録集

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] ヒト日周リズムの位相振動子モデル-階層をたどる枠組み-2003

    • Author(s)
      中尾
    • Journal Title

      第42回日本エム・イー学会大会論文集

      Pages: 161-161

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] ブラインド信号分離を点時系列に使ってみる2003

    • Author(s)
      中尾, 片山, 山本他
    • Journal Title

      第17回日本エム・イー学会秋季大会論文集

      Pages: 71-71

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] ラットの感覚毛除去によるバレル野の睡眠時脳波ダイナミクスの変化2003

    • Author(s)
      中尾, 片山, 山本他
    • Journal Title

      電子情報通信学会技術研究報告MEとバイオサイバネティクス研究会

    • NAID

      110003286577

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] 生体リズムの分子機構モデル2003

    • Author(s)
      中尾, 片山, 山本他
    • Journal Title

      電子情報通信学会技術研究報告MEとバイオサイバネティクス研究会

    • NAID

      110003286576

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Period and phase adjustments of human circadian rhythms in the real world.2003

    • Author(s)
      M.Nakao et al.
    • Journal Title

      J.Biol.Rhythms 18-3

      Pages: 261-270

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Modeling feedbacks from behavior to pacemakers in non-photic entrainment of human circadian system.2003

    • Author(s)
      M.Nakao
    • Journal Title

      Circadian Clock as Multi-oscillation System.(K.Honma and S.Honma eds)(Hokkaido University Press, Sapporo)

      Pages: 219-231

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] State-dependent alternation of neuronal slow dynamics in the rat ventroposterior thalamic area.2003

    • Author(s)
      M.Yamamoto et al.
    • Journal Title

      Sleep and Biological Rhythms 1-2

      Pages: 101-103

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] A facial topographic profile of rapid eys movements anticipatory phasic potentials.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Sleep and Biological Rhythms 1-2

      Pages: 151-152

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Changes in the dynamics of sleep electroencephalogram in rat barrel cortex associated with long-term sensory deprivation.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Sleep and Biological Rhythms 1-2

      Pages: 155-157

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] A real-time rapid eye movement sleep analyzer equipped with a portable wide-band polygraphic recorder.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Sleep and Biological Rhythms 1-2

      Pages: 175-177

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Temporal relationship between hippocampal theta wave and spontaneous and elicited PGO-like wave during REM sleep in rats.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Neuroscience Research 46(Suppl)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Fluctuational dynamics of a neural network model consisting of Hodgkin-Huxley type neurons driven by noise.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Neuroscience Research 46(Suppl)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Potine phasic activity is phase-locked to hippocampal theta wave during REM sleep in rats.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Proc.17^<th> Ann.Meeting Ass.Prof.Sleep Soc. 3

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Do the processor neurons in the rat brain show the 1/f noise like dynamics during paradoxical sleep.2003

    • Author(s)
      M.Yamamoto et al.
    • Journal Title

      Proc.17^<th> Ann.Meeting Ass.Prof.Sleep Soc. 28

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Non-monotonic changes of sleep EEG dynamics in rat barrel cortex associated with long-term sensory deprivation.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Proc.17^<th> Ann.Meeting Ass.Prof.Sleep Soc. 30

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Formal similarity between the two process model and a coupled oscillator model.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Proc.17^<th> Ann.Meeting Ass.Prof.Sleep Soc. 98

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Modeling of interactions between photic and non-photic entrainment mechanisms in time zone flights.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Abstracts 1^<st> World Congress Chronobiology E2-2

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Stability of rhythm trajectory generated by feedback loop models.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Abstracts 1^<st> World Congress Chronobiology E2-1

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Temporal relationship between rat's P wave and theta wave in paradoxical sleep.2003

    • Author(s)
      M.Nakao, A.Karashima, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Abstracts of 28^<th> JSSR 2B1-3

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Dynamics of molecular clock mechanisms.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Abstracts of 28^<th> JSSR 1P2-12

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Long term changes in statistical features of the barrel cortex by sensory deprivation.2003

    • Author(s)
      M.Nakao, A.Karashima, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Abstracts of 28^<th> JSSR 2P6-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Occular motion-dependency of spike potentials preceding the eye movements in sleep and waking states.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Abstracts of 28^<th> JSSR 2P6-18

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] A phase oscillator model of human circadian rhythms -an attempt to tracking the hierarchy-2003

    • Author(s)
      M.Nakao
    • Journal Title

      Abstracts of 42^<nd> JSMBE 161

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] An attempt to apply the blind source separation method to point processes.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      Abstracts of 18th fall meeting of JSMBE 161

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] Dynamics change in sleep EEG activity of the barrel cortex with the rat's whiskers clipped.2003

    • Author(s)
      M.Nakao, A.Karashima, N.Katayama, M.Yamamoto et al.
    • Journal Title

      IEICE Tehcnical Report MBE2003-11

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Journal Article] A model of molecular mechanisms of biological rhythms.2003

    • Author(s)
      M.Nakao, N.Katayama, M.Yamamoto et al.
    • Journal Title

      IEICE Tehcnical Report MBE2003-10

    • NAID

      110003286576

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Book] 生体リズムとゆらぎ2004

    • Author(s)
      中尾他
    • Total Pages
      171
    • Publisher
      コロナ社
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Annual Research Report 2004 Final Research Report Summary
  • [Book] Biological Rhythms and Fluctuations.2004

    • Author(s)
      M.Nakao, M.Yamamoto
    • Publisher
      Corona Publishing Co., Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Book] Modeling techniques of point processes and application in processing biomedical data.2003

    • Author(s)
      M.Nakao, M.Yamamoto et al.
    • Total Pages
      388
    • Publisher
      Kluwer Academic Publishers
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Book] Computational Methods in Biophysics, Biomaterials, Biotechnology and Medical Systems Vol.1(T.Leondes ed.)2003

    • Author(s)
      M.Nakao, M.Yamamoto
    • Publisher
      Kluwer Academic Publishers
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2004 Final Research Report Summary
  • [Publications] M.Nakao et al.: "Period and phase adjustments of human circadian rhythms in the real world"J.Boil.Rhythms. 18・3. 261-270 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Nakao: "Modeling feedbacks from behavior to pacemakers in non-photic entrainment of human circadian system"K.Honma and S.Honma eds, "Circadian Clock as Multi-oscillation System. Hokkaido University Press, Sapporo. 219-231 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Yamamoto et al.: "State-dependent alternation of neuronal slow dynamics in the rat ventroposterior thalamic area"Sleep and Biological Rhythms. 1・2. 101-103 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Nakao, N.Katayama, M.Yamamoto et al.: "A facial topographic profile of rapid eys movements anticipatory phasic potentials"Sleep and Biological Rhythms. 1・2. 151-152 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Nakao, N.Katayama, M.Yamamoto et al.: "Changes in the dynamics of sleep electoencephalogram in rat barrel cortex associated with long-term sensory deprivation"Sleep and Biological Rhythms. 1・2. 155-157 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Nakao, N.Katayama, M.Yamamoto et al.: "A real-time rapid eye movement sleep analyzer equipped with portable wide-band polygraphic recorder"Sleep and Biological Rhythms. 1・2. 175-177 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Yamamoto et al.: "Is state-dependent alternation of slow dynamics in central single neurons during sleep present in the rat ventroposterior thalamic nucleus?"Neuroscience Research. (in press).

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Nakao, N.Katayama, M.Yamamoto et al.: "Characterization of baroreflex response under head-up tilting"Proc. 25^<th> Ann Int'l Conf IEEE EMBS. 256-259 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Nakao, N.Katayama, M.Yamamoto et al.: "Temporal relationship between hippocampal theta wave and spontaneous and elicited PGO-like wave during REM sleep in rats"Neuroscience Research. 46・Suppl 1. S107 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Nakao, N.Katayama, M.Yamamoto et al.: "Fluctuational dynamics of a neural network model consisting of Hodgkin-Huxley type neurons driven by noise"Neuroscience Research. 46・Suppl 1. S166 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Nakao, N.Katayama, M.Yamamoto et al.: "Potine phasic activity is phase-locked to hippocampal theta wave during REM sleep in rats"Proc. 17^<th> Ann. Meeting Ass. Prof.Sleep Soc.. 3 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Yamamoto et al.: "Do the processor neurons in the rat brain show the 1/f noise like dynamics during paradoxical sleep"Proc. 17^<th> Ann. Meeting Ass. Prof. Sleep Soc.. 28 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Nakao, N.Katayama, M.Yamamoto et al.: "Non-monotonic changes of sleep EEG dynamics in rat barrel cortex associated with long-term sensory deprivation"Proc. 17^<th> Ann. Meeting Ass. Prof. Sleep Soc.. 30 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Nakao, N.Katayama, M.Yamamoto et al.: "Formal similarity between the two process model and a coupled oscillator model"Proc. 17^<th> Ann. Meeting Ass. Prof. Sleep Soc.. 98-99 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Nakao, N.Katayama, M.Yamamoto et al.: "Modeling of interactions between photic and non-photic entrainment mechanisms in time zone flights"Abstracts 1^<st> World Congress Chronobiology. E2-2 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Nakao, N.Katayama, M.Yamamoto et al.: "Stability of rhythm trajectory generated by feedback loop models"Abstracts 1^<st> World Congress Chronobiology. E2-1 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 中尾, 片山, 山本 他: "逆説睡眠時に観測されるラットP波頻度と海馬θ波周波数との時間関係"日本睡眠学会第28回定期学術集会抄録集. 2B1-2B3 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 中尾, 片山, 山本 他: "分子時計機構のダイナミクス"日本睡眠学会第28回定期学術集会抄録集. 1P2-1P12 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 中尾, 片山, 山本 他: "感覚遮断によるバレル野脳波の統計的性質の長期的変化"日本睡眠学会第28回定期学術集会抄録集. 2P6-2P6 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 中尾, 片山, 山本 他: "睡眠時及び覚醒時の眼球運動に先行するスパイク電位の眼球運動依存性"日本睡眠学会第28回定期学術集会抄録集. 2P6-2P18 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 中尾: "ヒト日周リズムの位相振動子モデル-階層をたどる枠組み-"第42回日本エム・イー学会大会論文集. 161 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 中尾, 片山, 山本 他: "ブラインド信号分離を点時系列に使ってみる"第27回日本エム・イー学会秋季大会論文集. 71 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 中尾, 片山, 山本 他: "ラットの感覚毛除去によるバレル野の睡眠時脳波ダイナミクスの変化"電子情報通信学会技術研究報告MEとバイオサイバネティクス研究会. MBE2003-11 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] 中尾, 片山, 山本 他: "生体リズムの分子機構モデル"電子情報通信学会技術研究報告MEとバイオサイバネティクス研究会. MBE2003-10 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] M.Nakao, M.Yamamoto et al.: "Modeling techniques of point processes and application in processing biomedical data"T.Leondes ed. "Computational Methods in Biophysics, Biomaterials, Biotechnology and Medical Systems Vol.1", Kluwer Academic Publishers. 263-326 (2003)

    • Related Report
      2003 Annual Research Report

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Published: 2003-04-01   Modified: 2016-04-21  

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