Basic research for wavefront-guided refractive surgery : The evaluation of effects of aberrations and scatterings on the optical function of the eye
| Project/Area Number |
15591854
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Osaka University |
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Principal Investigator |
MAEDA Naoyuki Osaka University, Graduate School of Medicine, Endowed Chair Professor, 医学系研究科, 寄附講座教授 (00273623)
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| Co-Investigator(Kenkyū-buntansha) |
NISHIDA Kohji Tohoku University, Graduate School of Medicine, Professor, 医学系研究科, 教授 (40244610)
FUJIKADO Takashi Osaka University, Graduate School of Medicine, Professor, 医学系研究科, 教授 (50243233)
TANO Yasuo Osaka University, Graduate School of Medicine, Professor, 医学系研究科, 教授 (80093433)
渡辺 仁 大阪大学, 医学系研究科, 助教授 (60252673)
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| Project Period (FY) |
2003 – 2005
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| Project Status |
Completed (Fiscal Year 2005)
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| Budget Amount *help |
¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 2005: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 2004: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 2003: ¥1,700,000 (Direct Cost: ¥1,700,000)
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| Keywords | wavefront technology / refractive surgery / aberration / scattering / visual function / irregular astigmatism / wavefront sensor / excimer laser |
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| Research Abstract |
As one of the cause of post-operative complications, the mechanism of transient keratectasia in association with a marked intraocular pressure (IOP) elevation was shown.
Monocular triplopia was reported by middle-aged patients with mild nuclear cataract and high myopia. Wavefront analyses suggested that the triple configuration was caused by the combined increase of the trefoil and spherical aberration in lenses with nuclear cataract.
The transplantation of tissue-engineered epithelial cell sheets can successfully prevent the development of corneal haze after excimer laser keratectomy.
The tear break-up time measured by Hartmann-Shack aberrometer may be used as a practical measure of tear break-up.
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Report
(4 results)
Research Products
(16 results)
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[Journal Article] Transplantation of tissue-engineered epithelial cell sheets after excimer laser photoablation reduces postoperative corneal haze.2006
Author(s)
Hayashida Y, Nishida K, Yamato M, Yang J, Sugiyama H, Watanabe K, Hon Y, Maeda N, Kikuchi A, Okano T, Tano Y
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Journal Title
Invest Ophthalmol Vis Sci. 47
Pages: 552-557
Description
「研究成果報告書概要(欧文)」より
Related Report
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