| Budget Amount *help |
¥42,770,000 (Direct Cost: ¥32,900,000、Indirect Cost: ¥9,870,000)
Fiscal Year 2017: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
Fiscal Year 2016: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
Fiscal Year 2015: ¥21,190,000 (Direct Cost: ¥16,300,000、Indirect Cost: ¥4,890,000)
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| Outline of Final Research Achievements |
Based on the chemical reactions developed by us, the studies on highly efficient detection methods for epigenetic modifications have been carried out. The results are as follows: (i) Highly bright detection of methylation in DNA repeat sequences to understand heterogeneity in tumors, (ii) High performance analysis of the products in demethylation process to make prognostication for tumors efficient, (iii) Chemical reproduction and analysis of histone structures for control of gene expression.
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