Complementary use of augmented reality and 3D printing to improve the effectiveness and safety of interventional radiology procedures

• Project/Area Number: 15H02553
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Radiation science
• Research Institution: International University of Health and Welfare (2016-2020); The University of Tokyo (2015)
• Principal Investigator: Ohtomo Kuni 国際医療福祉大学, 本部, 学長 (80126010)
• Co-Investigator(Kenkyū-buntansha): 高尾 英正 東京大学, 医学部附属病院, 准教授 (10444093)
• Project Period (FY): 2015-04-01 – 2020-03-31
• Project Status: Completed (Fiscal Year 2020)
• Budget Amount: ¥31,070,000 (Direct Cost: ¥23,900,000、Indirect Cost: ¥7,170,000); Fiscal Year 2019: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000); Fiscal Year 2018: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000); Fiscal Year 2017: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2016: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000); Fiscal Year 2015: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
• Keywords: 放射線 / IVR

Outline of Final Research Achievements

The aim of this research was to apply the technologies of augmented reality (AR) and three-dimensional (3D) printing to the field of interventional radiology for the improvement of the effectiveness and safety of interventional radiology procedures. We established a method of creating three-dimensional printing simulation models and evaluated them for simulation of interventional radiology procedures such as endovascular treatment. In addition, we developed an augmented reality system to project three-dimensional images reconstructed from radiological images such as computed tomography (CT) onto a monitor with three-dimensional printing models used for evaluation of the system. We are planning to continue to further improve the system.

Academic Significance and Societal Importance of the Research Achievements

画像下治療（Interventional Radiology）は、低侵襲な治療・手技ではあるが、他の選択肢との優位性を示すためには、有効性および安全性の向上が不可欠である。通常、画像ガイドに使用する画像は二次元であり、三次元プリンティングによるシミュレーションモデルや仮想現実システムにて、術前および術中において、三次元の情報を活用することにより、手技の有効性（治療成績）および安全性の向上につながると期待される。

Research Products

• [Journal Article] Triple-balloon-assisted n-butyl-2-cyanoacrylate embolization of a cirsoid renal arteriovenous malformation (2020)
  • Author(s): Takao H, Abe O.
  • Journal Title: Vasa Volume: 49 Issue: 2 Pages: 147-150
  • DOI: 10.1024/0301-1526/a000817
  • Peer Reviewed
• [Journal Article] Embolization of visceral arterial aneurysms: Simulation with 3D-printed models. (2020)
  • Author(s): Shibata E, Takao H, Amemiya S, Ohtomo K, Abe O.
  • Journal Title: Vacular Volume: 28 Issue: 3 Pages: 259-266
  • DOI: 10.1177/1708538119900834
  • Peer Reviewed / Open Access
• [Journal Article] Double-balloon-assisted n-butyl-2-cyanoacrylate embolization of non-tumorous intrahepatic arterioportal shunts. (2019)
  • Author(s): Takao H, Shibata E, Amemiya S, Abe O.
  • Journal Title: J Vasc Interv Radiol. Volume: 印刷中 Issue: 8 Pages: 1210-1214.e2
  • DOI: 10.1016/j.jvir.2019.04.011
  • Peer Reviewed
• [Journal Article] 3D printing of preoperative simulation models of a splenic artery aneurysm: Precision and accuracy. (2017)
  • Author(s): Takao H, Amemiya S, Shibata E, Ohtomo K.
  • Journal Title: Acad Radiol. Volume: 24 Issue: 5 Pages: 650-653
  • DOI: 10.1016/j.acra.2016.12.015
  • Peer Reviewed
• [Journal Article] 3D-printed visceral aneurysm models based on CT data for simulations of endovascular embolization: Evaluation of size and shape accuracy. (2017)
  • Author(s): Shibata E, Takao H, Amemiya S, Ohtomo K.
  • Journal Title: AJR Am J Roentgenol. Volume: 209 Issue: 2 Pages: 243-247
  • DOI: 10.2214/ajr.16.17694
  • Peer Reviewed
• [Journal Article] Perioperative hemodynamic monitoring of common hepatic artery for endovascular embolization of a pancreaticoduodenal arcade aneurysm with celiac stenosis. (2017)
  • Author(s): Shibata E, Takao H, Amemiya S, Ohtomo K.
  • Journal Title: Cardiovasc Intervent Radiol. Volume: 40 Issue: 3 Pages: 465-469
  • DOI: 10.1007/s00270-016-1517-9
  • Peer Reviewed
• [Journal Article] Double-balloon-assisted n-butyl-2-cyanoacrylate embolization of intrahepatic arterioportal shunt prior to chemoembolization of hepatocellular carcinoma. (2016)
  • Author(s): Takao H, Shibata E, Ohtomo K.
  • Journal Title: Cardiovasc Intervent Radiol. Volume: 39 Issue: 10 Pages: 1479-1483
  • DOI: 10.1007/s00270-016-1377-3
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Three-dimensional printing of hollow portal vein stenosis models: A feasibility study. (2016)
  • Author(s): Takao H, Amemiya S, Shibata E, Ohtomo K.
  • Journal Title: J Vasc Interv Radiol. Volume: 27 Issue: 11 Pages: 1755-1758
  • DOI: 10.1016/j.jvir.2016.05.022
  • Peer Reviewed / Acknowledgement Compliant
• [Presentation] Applications of 3D printing to radiology and interventional radiology. (2019)
  • Author(s): Takao H, Shibata E, Amemiya S, Ohtomo K, Abe O.
  • Organizer: ECR (European Congress of Radiology)
  • Int'l Joint Research
• [Presentation] 肝動脈門脈シャントに対するダブルバルーン補助下のNBCA塞栓． (2018)
  • Author(s): 高尾英正、柴田英介、雨宮史織、阿部修．
  • Organizer: 日本医学放射線学会秋季臨床大会
• [Presentation] ３Ｄプリンタの医療応用：セグメンテーションから３Ｄモデル出力まで． (2017)
  • Author(s): 高尾英正．
  • Organizer: 日本医学放射線学会秋季臨床大会
  • Invited
• [Presentation] Embolic agents: Relationships between agent type and target vessel size and nature. (2017)
  • Author(s): Takao H, Abe O.
  • Organizer: RSNA (Radiological Society of North America)
  • Int'l Joint Research
• [Presentation] 3D printing in radiology and interventional radiology. (2017)
  • Author(s): Takao H, Shibata E, Amemiya S, Ohtomo K, Abe O.
  • Organizer: RSNA (Radiological Society of North America)
  • Int'l Joint Research
• [Presentation] Preoperative endovascular embolization hepatectomy with recent topics. (2017)
  • Author(s): 柴田英介、高尾英正、大倉直樹、佐藤次郎、大友邦、阿部修．
  • Organizer: 東京アンギオ・ＩＶＲ会
• [Presentation] 胎盤ボリープ出血に対して超選択的塞栓術を施行した1例． (2017)
  • Author(s): 柴田英介、高尾英正、他．
  • Organizer: 日本IVR学会総会
• [Presentation] Simulation of endovascular embolization for visceral artery aneurysms with 3D-printed hollow models. (2017)
  • Author(s): Shibata E, Takao H, Amemiya S, Abe O, Ohtomo K.
  • Organizer: CIRSE (Cardiovascular and Interventional Radiological Society of Europe)
  • Int'l Joint Research
• [Presentation] NBCA embolization of a true splenic artery aneurysm: simulation with a 3D-printed model and treatment. (2017)
  • Author(s): Shibata E, Takao H, Amemiya S, Abe O, Ohtomo K.
  • Organizer: CIRSE (Cardiovascular and Interventional Radiological Society of Europe)
  • Int'l Joint Research
• [Presentation] Superselective embolization of bleeding placental polyps. (2017)
  • Author(s): Shibata E, Takao H, Shirota G, Kawai G, Abe O.
  • Organizer: CIRSE (Cardiovascular and Interventional Radiological Society of Europe)
  • Int'l Joint Research
• [Presentation] The creation and utilization of 3D printed models for endovascular embolization of visceral aneurysms. (2016)
  • Author(s): Shibata E, Takao H, Amemiya S, Ohtomo K.
  • Organizer: RSNA (Radiological Society of North America)
  • Place of Presentation: Chicago (USA)
  • Year and Date: 2016-11-27
  • Int'l Joint Research
• [Presentation] Simulation of embolization of visceral aneurysms with 3D-printed hollow models. (2016)
  • Author(s): Shibata E, Takao H, Amemiya S, Ohtomo K.
  • Organizer: CIRSE (Cardiovascular and Interventional Radiological Society of Europe)
  • Place of Presentation: Barcelona (Spain)
  • Year and Date: 2016-09-10
  • Int'l Joint Research
• [Presentation] Stent placement for portal vein stenosis. (2016)
  • Author(s): Shibata E, Okura N, Takao H, Sato J, Ohtomo K,
  • Organizer: CIRSE (Cardiovascular and Interventional Radiological Society of Europe)
  • Place of Presentation: Barcelona (Spain)
  • Year and Date: 2016-09-10
  • Int'l Joint Research
• [Presentation] Preoperative endovascular embolization for hepatectomy and pancreatectomy; In relation to recent surgical treatment in cancer. (2016)
  • Author(s): Shibata E, Takao H, Okura N, Sato J, Ohtomo K.
  • Organizer: German-Japanese Radiological Affiliation
  • Place of Presentation: Munich (Germany)
  • Year and Date: 2016-06-02
  • Int'l Joint Research
• [Presentation] 3Dプリンターにて作成した血管内腔モデルにて術前シミュレーションを 行った脾動脈瘤塞栓の一例． (2016)
  • Author(s): 柴田英介、高尾英正、雨宮史織、神谷昂平、大倉直樹、赤松展彦、西原陽介、佐藤次郎、大友邦．
  • Organizer: 日本IVR学会総会
  • Place of Presentation: ウェスティンナゴヤキャッスル（愛知県名古屋市）
  • Year and Date: 2016-05-25
• [Presentation] ３Ｄプリンターによる脾動脈瘤の術前シミュレーションモデルの精度と確度． (2016)
  • Author(s): 高尾英正、雨宮史織、柴田英介、大友邦．
  • Organizer: 日本医学放射線学会総会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2016-04-14
• [Presentation] CTデータから作成した腹部内蔵動脈瘤の3Dプリンターモデルの正確性の検討． (2016)
  • Author(s): 柴田英介、高尾英正、雨宮史織、大友邦．
  • Organizer: 日本医学放射線学会総会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2016-04-14
• [Presentation] CTデータから作成した腹部内蔵動脈瘤の3Dプリンターモデルの正確性の検討 (2016)
  • Author(s): 柴田英介、高尾英正、雨宮史織、大友邦
  • Organizer: 日本医学放射線学会総会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2016-04-14
• [Presentation] ３Ｄプリンターによる脾動脈瘤の術前シミュレーションモデルの精度と確度 (2016)
  • Author(s): 高尾英正、雨宮史織、柴田英介、大友邦
  • Organizer: 日本医学放射線学会総会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2016-04-14