| Budget Amount *help |
¥40,950,000 (Direct Cost: ¥31,500,000、Indirect Cost: ¥9,450,000)
Fiscal Year 2019: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2018: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
Fiscal Year 2017: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
Fiscal Year 2016: ¥8,710,000 (Direct Cost: ¥6,700,000、Indirect Cost: ¥2,010,000)
Fiscal Year 2015: ¥11,570,000 (Direct Cost: ¥8,900,000、Indirect Cost: ¥2,670,000)
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| Outline of Final Research Achievements |
In this study, we elucidated the function and mechanism of the transcription factor Mkx, which is specific to the tendons and ligaments, for the development and maintenance of tendon and ligament tissues. Toward this purpose, we created Mkx gene-modified rats and used them to elucidate the maintenance and regeneration signals of tendons and ligaments via Mkx, clarifying the molecular network of tendons and ligaments.
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