| Budget Amount *help |
¥16,640,000 (Direct Cost: ¥12,800,000、Indirect Cost: ¥3,840,000)
Fiscal Year 2017: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
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| Outline of Final Research Achievements |
In many cell types, the cell nucleus is positioned at the center of the cell. The mechanism to position the nucleus at the cell center is still under debate. In this research project, we obtained results to support ‘cytoplasmic pulling model’, in which the nucleus moves toward the cell center by the pulling force produced throughout the cytoplasm. Moreover, we have succeeded to measure the forces required to move the nucleus in a living cell. These achievements advanced the mechanism for the positioning of cell nucleus at the cell center.
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