Elucidation of odor representation in insects through a detailed modeling of insect olfactory network
| Project/Area Number |
15H04399
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Animal physiology/Animal behavior
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| Research Institution | The University of Tokyo |
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Principal Investigator |
Kanzaki Ryohei 東京大学, 先端科学技術研究センター, 教授 (40221907)
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| Co-Investigator(Renkei-kenkyūsha) |
KAZAWA Tomoki 東京大学, 先端科学技術研究センター, 特任研究員 (00507824)
SAKURAI Takeshi 東京大学, 先端科学技術研究センター, 特任講師 (20506761)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Fiscal Year 2017: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2016: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
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| Keywords | 脳・神経 / シミュレーション / 遺伝子 / データ同化 / 昆虫 |
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| Outline of Final Research Achievements |
In this study, we aimed to understand neural mechanisms to process dynamically changing pheromone information in the antennal lobe of male silkmoths. We generated several transgenic silkmoth lines that are useful for investigating functional connectivity of neurons in the antennal lobe of silkmoths. Based on experimental data, we constructed single compartment and multi-compartment simulation models of the antennal lobe of male silkmoths. We demonstrated that these simulation models can reproduce experimentally observed phenomena such as modulation of pheromone responses of the antennal lobe projection neurons to successive pheromone stimuli or by mechanosensory input to antennae.
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Report
(4 results)
Research Products
(57 results)
