Investigation of the mycoparacite related metabolites
Project/Area Number |
15H04491
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Bioorganic chemistry
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Research Institution | Hirosaki University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
殿内 暁夫 弘前大学, 農学生命科学部, 教授 (50302021)
田中 和明 弘前大学, 農学生命科学部, 准教授 (60431433)
|
Project Period (FY) |
2015-04-01 – 2019-03-31
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Project Status |
Completed (Fiscal Year 2018)
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Budget Amount *help |
¥15,860,000 (Direct Cost: ¥12,200,000、Indirect Cost: ¥3,660,000)
Fiscal Year 2018: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2017: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2016: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2015: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
|
Keywords | マイコパラサイト / 菌間コミュニケーション / 二次代謝物 / ハイブリッド化合物 / ハイブリッド二次代謝物 / マイコパラサイト支配物質 / cyclohelminthol X / cyclohelminthol Y / neomacrophorin X / 機構解明 / ネオマクロフォリンX / 生合成 / グリセオフルビン / Calcarisporium arbuscula / ロリジン / カエンタケ |
Outline of Final Research Achievements |
Sometimes fungi intrude other fungus and this phenomenon is called Mycoparasitism. However, no chemical investigations were performed to reveal the mechanism. Recently the authors succeeded in revealing the responsible chemical to the mycoparasitism on apple fruits. However, that is one example but there must be other chemical communication on the inter fungal relationship. Discovery of the novel responsible molecules are expected to be utilized not only for agricultural industries but also for medicinal usage. With the aim as described, mycoparasitism related molecules were investigated.
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Academic Significance and Societal Importance of the Research Achievements |
菌類は他の生命に寄生することで生存するが、菌に対して寄生することもあり、他の菌を攻撃するとき、さまざまな物質を用いていると想定される。まずは、菌寄生に重要な役割を果たす化合物を見出し、菌が菌に新入する機構を分子レベルで解明することは学術的に意義深い。それら物質は抗菌剤や抗ウイルス剤としての利用も期待でき、農薬医薬分野で応用することが可能である。
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Report
(5 results)
Research Products
(107 results)
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[Journal Article] Biosynthetic study of conidiation-inducing factor conidiogenone: Heterologous production and cyclization mechanism of a key bifunctional diterpene synthase2019
Author(s)
Shiina, T.; Nakagawa, K.; Fujisaki, Y.; Ozaki, T.; Liu, C.; Toyomasu, T.; Hashimoto, M.; Koshino, H.; Minami, A.; Kawaide, H.; Oikawa, H.
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Journal Title
Biosci. Biotechnol. Biochem.
Volume: 83
Issue: 2
Pages: 192-201
DOI
Related Report
Peer Reviewed
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[Journal Article] Capsulimonas corticalis gen. nov., sp. nov., an aerobic capsulated bacterium, of a novel bacterial order, Capsulimonadales ord. nov., of the class Armatimonadia of the phylum Armatimonadetes.2019
Author(s)
Li, J., Kudo, C., Tonouchi, A.:
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Journal Title
Int. J. Syst. Evol. Microbiol.
Volume: 69
Issue: 1
Pages: 220-226
DOI
Related Report
Peer Reviewed
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[Journal Article] Notes for genera: Ascomycota2017
Author(s)
Wijayawardene NN, Hyde KD, Rajeshkumar KC et al. (K. Tanaka 32番目/97名中)
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Journal Title
Fungal Diversity
Volume: 86
Issue: 1
Pages: 1-594
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Dictyosporiaceae fam. nov.2016
Author(s)
Boonmee S, D’souza MJ, Luo Z, Pinruan U, Tanaka K, Su H, Bhat DJ, McKenzie EHC, Jones EBG, Taylor JE, Phillips AJL, Hirayama K, Eungwanichayapant PD, Hyde KD
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Journal Title
Fungal Diversity
Volume: 80
Issue: 1
Pages: 457-482
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Taxonomy and phylogeny of dematiaceous coelomycetes2016
Author(s)
Wijayawardene NN, Hyde KD, Wanasinghe DN, Papizadeh M, Goonasekara ID, Camporesi E, Bhat DJ, McKenzie EHC, Phillips AJL, Diederich P, Tanaka K, Li WJ, Tangthirasunun N, Phookamsak R, Dai DQ, Dissanayake AJ, Weerakoon G, Maharachchikumbura SSN, Hashimoto A, Matsumura M, Bahkali AH, Wang Y
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Journal Title
Fungal Diversity
Volume: 77
Issue: 1
Pages: 1-316
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Isolation, ECD assisted structural analyses, biosynthetic discussions, and biological activities of epi-cochlioquinones D and its derivatives2015
Author(s)
M Arayama, T Nehira, H Maeda, K Tanaka, H Miyagawa, T Ueno, S Hosokawa, M Hashimoto
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Journal Title
Tetrahedron
Volume: 71(29)
Issue: 29
Pages: 4788-4794
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Draft genome sequence of Bacteroidales srain 6E isolated from a rice paddy field in Japan.2015
Author(s)
Tourlousse, D., Honda, T., Matsuura, N., Ohashi, A., Tonouchi, A., Sekiguchi, Y.
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Journal Title
Genome Announcements
Volume: 3
Issue: 5
DOI
Related Report
Peer Reviewed
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[Journal Article] Hashimoto A, Sato G, Matsuda T, Matsumura M, Hatakeyama S, Harada Y, Ikeda H, Tanaka K2015
Author(s)
Hashimoto A, Sato G, Matsuda T, Matsumura M, Hatakeyama S, Harada Y, Ikeda H, Tanaka K
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Journal Title
Mycologia
Volume: 107
Issue: 2
Pages: 383-408
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Minutisphaerales (Dothideomycetes, Ascomycota): a new order of freshwater ascomycetes including a new family, Minutisphaeraceae, and two new species from North Carolina, USA.2015
Author(s)
Raja HA, El-Elimat T, Oberlies NH, Shearer CA, Miller AN, Tanaka K, Hashimoto A, Fournier J
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Journal Title
Mycologia
Volume: 107
Issue: 4
Pages: 845-862
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Towards a natural classification of Astrosphaeriella-like species; introducing Astrosphaeriellaceae and Pseudoastrosphaeriellaceae fam. nov. and Astrosphaeriellopsis, gen. nov.2015
Author(s)
Phookamsak R, Norphanphoun C, Tanaka K, Dai DQ, Luo ZL, Liu JK, Su HY, Bhat DJ, Bahkali AH, Mortimer PE, Xu JC, Hyde KD
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Journal Title
Fungal Diversity
Volume: 74
Issue: 1
Pages: 143-197
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Towards a natural classification and backbone tree for Lophiostomataceae, Floricolaceae, and Amorosiaceae fam. nov.2015
Author(s)
Thambugala KM, Hyde KD, Tanaka K, Tian Q, Wanasinghe DN, Ariyawansa HA, Jayasiri SC, Boonmee S, Camporesi E, Hashimoto A, Hirayama K, Schumacher RK, Promputtha I, Liu ZY
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Journal Title
Fungal Diversity
Volume: 74
Issue: 1
Pages: 199-266
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Revision of the Massarineae (Pleosporales, Dothideomycetes).2015
Author(s)
Tanaka K, Hirayama K, Yonezawa H, Sato G, Toriyabe A, Kudo H, Hashimoto A, Matsumura M, Harada Y, Kurihara Y, Shirouzu T, Hosoya T
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Journal Title
Studies in Mycology
Volume: 82
Issue: 1
Pages: 75-136
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Presentation] Isolation, ECD Assisted Structural Analyses, Biosynthetic Discussions, and Biological activities of epi-Cochlioquinones D and its Derivatives2015
Author(s)
M. Arayama, T. Nehira, H. Maeda, K. Tanaka, H. Miyagawa, T. Ueno, S. Hosokawa, M. Hashimoto,
Organizer
15th International Conference on Chiral Spectroscopy
Place of Presentation
札幌
Year and Date
2015-08-31
Related Report
Int'l Joint Research
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