Influence of nutritional status on amino acid glycation in the chicken with high blood glucose
| Project/Area Number |
15H04580
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Animal production science
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| Research Institution | Iwate University |
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Principal Investigator |
Kita Kazumi 岩手大学, 農学部, 教授 (20221913)
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| Co-Investigator(Kenkyū-buntansha) |
西向 めぐみ 岩手大学, 農学部, 准教授 (40374730)
村岡 宏樹 岩手大学, 理工学部, 助教 (50546934)
平松 浩二 信州大学, 学術研究院農学系, 教授 (80238386)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000)
Fiscal Year 2017: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2016: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
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| Keywords | 糖化反応 / ニワトリ / アマドリ化合物 / 栄養 / 栄養学 |
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| Outline of Final Research Achievements |
As chickens are hyperglycemic animals, amino acids bind non-enzymatically to glucose leading to form Amadori products. In this study, physiological roles of Amadori products in chickens were examined in vivo. When experimental diets containing various protein levels (crude protein 0%, 10%, 20% (Control), 40% and 60%) were given to young chickens, the ratio of plasma valine-Amadori product concentration to plasma valine concentration was significantly increased by the decrease in dietary crude protein levels. It was revealed that half-life of valine-Amadori product in the plasma was estimated to be 277 min by investigating the time course change of plasma valine-Amadori product concentration after intravenous administration of valine-Amadori product. Furthermore, it was shown that amino acid-Amadori product can be incorporated into chicken embryo derived cells.
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Report
(4 results)
Research Products
(17 results)
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[Journal Article] Influence of Varying Dietary Protein Levels on Glycation of Albumin, Tryptophan and Valine in the Plasma of Chickens2017
Author(s)
Honma, A., Ogawa, C., Sugahara1, M., Fujimura, S. and Kita, K.
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Journal Title
The Journal of Poultry Science
Volume: 54
Issue: 3
Pages: 242-246
DOI
NAID
ISSN
1346-7395, 1349-0486
Related Report
Peer Reviewed / Open Access
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[Journal Article] Glycated Tryptophan in the Plasma of Chickens Fed Tryptophan-excess Diets2015
Author(s)
Makino, R., Kawashima, Y., Kajita, Y., Namauo, T., Ogawa, S., Muraoka, H., Fujimura, S. and Kita, K.
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Journal Title
The Journal of Poultry Science
Volume: 52
Issue: 1
Pages: 23-27
DOI
NAID
ISSN
1346-7395, 1349-0486
Related Report
Peer Reviewed / Open Access
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