Identification of aldosterone-producing cells: Explore the novel mechanism of the hypertension-induced organ damages

• Project/Area Number: 15H04711
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Human pathology
• Research Institution: Tohoku University
• Principal Investigator: SASANO Hironobu 東北大学, 医学系研究科, 教授 (50187142)
• Co-Investigator(Renkei-kenkyūsha): NAKAMURA Yasuhiro 東北医科薬科大学, 医学部, 教授 (80396499) ; ARAI Yoichi 東北大学, 大学院医学系研究科, 教授 (50193058) ; SATOH Fumitoshi 東北大学, 医学系研究科, 特任教授 (70343051) ; MORIMOTO Ryo 東北大学, 大学病院, 講師 (30547394)
• Research Collaborator: Rainey William E ; Gomez-Sanchez Celso E ; ONO Katsuhiko ; ISE Kazue ; YAMAZAKI Yuto
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000); Fiscal Year 2017: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2016: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000); Fiscal Year 2015: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
• Keywords: アルドステロン / CYP11B2 / 高血圧 / 原発性アルドステロン症 / 免疫組織化学 / KCNJ5 / 副腎皮質球状層 / 副腎 / ステロイド / 病理学 / 画像解析 / 泌尿生殖器・内分泌 / 副腎皮質 / 次世代シークエンス

Outline of Final Research Achievements

In this present study, the novel histopathological classification of cross-sectional image negative non-neoplastic hyperaldosteronism has been proposed based on the distribution of aldosterone-producing cells. Furthermore, this is the first study to demonstrate that aldosterone-producing cell clusters (APC) frequently harbors aldosterone-driver gene somatic mutation and accumulate with age.

Research Products

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• [Journal Article] Acute Exacerbation of Idiopathic Pulmonary Fibrosis Following Treatment for Cushing's Syndrome (2016)
  • Author(s): Ohara N, Kaneko M, Sato K, Usuda H, Tanaka J, Maekawa T, Sasano H, Katakami H, Kaneko K, Kamoi K.
  • Journal Title: Internal Medicine Volume: 55 Issue: 4 Pages: 389-394
  • DOI: 10.2169/internalmedicine.55.5566
  • NAID: 130005125801
  • ISSN: 0918-2918, 1349-7235
  • Peer Reviewed / Open Access
• [Journal Article] Renal Resistive Index Predicts Postoperative Blood Pressure Outcome in Primary Aldosteronism. (2016)
  • Author(s): Iwakura Y, Ito S, Morimoto R, Kudo M, Ono Y, Nezu M, Takase K, Seiji K, Ishidoya S, Arai Y, Funamizu Y, Miki T, Nakamura Y, Sasano H, Satoh F.
  • Journal Title: Hypertension. Volume: 67 Issue: 3 Pages: 654-660
  • DOI: 10.1161/hypertensionaha.115.05924
  • Peer Reviewed / Open Access
• [Journal Article] Aldosterone-producing adrenocortical carcinoma with prominent hepatic metastasis diagnosed by liver biopsy: a case study. (2016)
  • Author(s): Ohashi K, Hayashi T, Sakamoto M, Iuchi H, Suzuki H, Ebisawa T, Tojo K, Sasano H, Utsunomiya K.
  • Journal Title: BMC Endocr Disord. Volume: 16 Issue: 1 Pages: 3-3
  • DOI: 10.1186/s12902-016-0083-0
  • Peer Reviewed / Open Access
• [Journal Article] 5th International ACC Symposium: An Outlook to Current and Future Research on the Biology of Adrenocortical Carcinoma: Diagnostic and Therapeutic Applications. (2016)
  • Author(s): Lalli E, Sasano H.
  • Journal Title: Horm Cancer. Volume: 7(1) Issue: 1 Pages: 44-48
  • DOI: 10.1007/s12672-015-0240-3
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Recommendations for description and validation for antibodies for research use. (2016)
  • Author(s): Rizner TL, Sasano H, Choi MH, Odermatt A, Adamski J.
  • Journal Title: J Steroid Biochem Mol Biol. Volume: 156 Pages: 40-42
  • DOI: 10.1016/j.jsbmb.2015.11.021
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Clinical and Steroidogenic Characteristics of Aldosterone-Producing Adenomas With ATPase or CACNA1D Gene Mutations. (2016)
  • Author(s): Kitamoto T, Suematsu S, Yamazaki Y, Nakamura Y, Sasano H, Matsuzawa Y, Saito J, Omura M, Nishikawa T
  • Journal Title: J Clin Endocrinol Metab Volume: Feb;101(2) Issue: 2 Pages: 494-503
  • DOI: 10.1210/jc.2015-3284
  • Peer Reviewed / Open Access
• [Journal Article] Intratumoral heterogeneity of steroidogenesis in aldosterone-producing adenoma revealed by intensive double- and triple-immunostaining for CYP11B2/B1 and CYP17. (2016)
  • Author(s): Nakamura Y, Kitada M, Satoh F, Maekawa T, Morimoto R, Yamazaki Y, Ise K, Gomez-Sanchez CE, Ito S, Arai Y, Dezawa M, Sasano H
  • Journal Title: Mol Cell Endocrinol Volume: 422 Pages: 57-63
  • DOI: 10.1016/j.mce.2015.11.014
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Extraordinarily high aldosterone, 901.0 ng/dL, in a patient with primary aldosteronism: an insight into the underlying mechanism (2016)
  • Author(s): Okubo Y, Sato Y, Nakasone Y, Shirotori K, Oguchi K, Matsushita T, Nishikawa T, Yamazaki Y, Sasano H, Komtasu M, Yamauchi K, Aizawa T.
  • Journal Title: Endocrine Journal Volume: 63 Issue: 2 Pages: 127-133
  • DOI: 10.1507/endocrj.EJ15-0398
  • NAID: 130005127195
  • ISSN: 0918-8959, 1348-4540
  • Peer Reviewed / Open Access
• [Journal Article] A case of bilateral aldosterone-producing adenomas differentiated by segmental adrenal venous sampling for bilateral adrenal sparing surgery. (2016)
  • Author(s): R Morimoto, N Satani, Y Iwakura, Y Ono, M Kudo, M Nezu, K Omata, Y Tezuka, K Seiji, H Ota, Y Kawasaki, S Ishidoya, Y Nakamura, Y Arai, K Takase, H Sasano, S Ito, F Satoh
  • Journal Title: Journal of human hypertension Volume: 30 Issue: 6 Pages: 379-385
  • DOI: 10.1038/jhh.2015.100
  • Peer Reviewed / Open Access
• [Journal Article] The Role of Androgen under Normal and Pathological Conditions in SebaceousGlands: The Possibility of Target Therapy. (2016)
  • Author(s): Azmahani A, Nakamura Y, McNamara KM, Sasano H.
  • Journal Title: Curr Mol Pharmacol. Volume: 9 Issue: 4 Pages: 311-319
  • DOI: 10.2174/1874467208666150710120217
  • Peer Reviewed / Open Access
• [Journal Article] A Calcitonin Non-producing Neuroendocrine Tumor of the Thyroid Gland. (2016)
  • Author(s): Kasajima A, Cameselle-Teijeiro J, Loidi L, Takahashi Y, Nakashima N, Sato S, Fujishima F, Watanabe M, Nakazawa T, Naganuma H, Kondo T, Kato R, Sasano H.
  • Journal Title: Endocr Pathol. Volume: -
  • Peer Reviewed
• [Journal Article] Triple Negative Breast Cancer Chemosensitivity and Chemoresistance: Current Advances in Biomarkers Indentification. (2016)
  • Author(s): Guestini F, McNamara KM, Ishida T, Sasano H.
  • Journal Title: Expert Opin Ther Targets. Volume: -
  • Peer Reviewed
• [Journal Article] Reply to comments to "Letter to the Editor: comment on Azmahani et al. steroidogenic enzymes, their related transcription factors and nuclear receptors in human sebaceous glands under normal and pathological conditions". (2016)
  • Author(s): Azmahani A, Nakamura Y, Felizola SJ, Ozawa Y, Ise K, Inoue T, McNamara KM, Doi M, Okamura H, Zouboulis CC, Aiba S, Sasano H.
  • Journal Title: J Steroid Biochem Mol Biol. Volume: 155（Pt A) Pages: 178-180
  • DOI: 10.1016/j.jsbmb.2015.09.028
  • Peer Reviewed / Open Access
• [Journal Article] Cushing Syndrome Due to ACTH-Secreting Pheochromocytoma, Aggravated by Glucocorticoid-Driven Positive-Feedback Loop. (2015)
  • Author(s): Sakuma I, Higuchi S, Fujimoto M, Takiguchi T, Nakayama A, Tamura A, Kohno T, Komai E, Shiga A, Nagano H, Hashimoto N, Suzuki S, Mayama T, Koide H, Ono K, Sasano H, Tatsuno I, Yokote K, Tanaka T.
  • Journal Title: J Clin Endocrinol Metab. Volume: 101(3) Issue: 3 Pages: 841-846
  • DOI: 10.1210/jc.2015-2855
  • Peer Reviewed / Open Access
• [Journal Article] Methylation Status of Vitamin D Receptor Gene Promoter in Benign and Malignant Adrenal Tumors. (2015)
  • Author(s): Pilon C, Rebellato A, Urbanet R, Guzzardo V, Cappellesso R, Sasano H, Fassina A, Fallo F.
  • Journal Title: Int J Endocrinol. Volume: 2015 Pages: 375349-375349
  • DOI: 10.1155/2015/375349
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Androgen receptor, androgen-producing enzymes and their transcription factors in extramammary Paget disease. (2015)
  • Author(s): Azmahani A, Nakamura Y, Ozawa Y, McNamara KM, Fujimura T, Haga T, Hashimoto A, Aiba S, Sasano H.
  • Journal Title: Hum Pathol. Volume: 46(11) Issue: 11 Pages: 1662-1669
  • DOI: 10.1016/j.humpath.2015.07.007
  • Peer Reviewed / Open Access
• [Journal Article] Abnormal expression of miR-1 in breast carcinoma as a potent prognostic factor. (2015)
  • Author(s): Minemura H, Takagi K, Miki Y, Shibahara Y, Nakagawa S, Ebata A, Watanabe M, Ishida T, Sasano H, Suzuki T.
  • Journal Title: Cancer Sci. Volume: 106(11) Issue: 11 Pages: 1642-1650
  • DOI: 10.1111/cas.12808
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Prognostic significance of proline, glutamic acid, leucine rich protein 1 (PELP1) in triple-negative breast cancer: a retrospective study on 129 cases. (2015)
  • Author(s): Zhang Y, Dai J, McNamara KM, Bai B, Shi M, Chan MS, Liu M, Sasano H, Wang X, Li X, Liu L, Ma Y, Cao S, Xing Y, Zhao B, Song Y, Wang L.
  • Journal Title: BMC Cancer. Volume: 15 Issue: 1 Pages: 699-699
  • DOI: 10.1186/s12885-015-1694-y
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Intracrine steroid production and mammalian target of rapamycin pathways in pulmonary lymphangioleiomyomatosis. (2015)
  • Author(s): Adachi K, Miki Y, Saito R, Hata S, Yamauchi M, Mikami Y, Okada Y, Seyama K, Kondo T, Sasano H.
  • Journal Title: Hum Pathol. Volume: 46(11) Issue: 11 Pages: 1685-1693
  • DOI: 10.1016/j.humpath.2015.02.019
  • Peer Reviewed / Open Access
• [Journal Article] Beyond the C18 frontier: Androgen and glucocorticoid metabolism in breast cancer tissues: The role of non-typical steroid hormones in breast cancer development and progression. (2015)
  • Author(s): McNamara KM, Sasano H.
  • Journal Title: Steroids. Volume: 103 Pages: 115-122
  • DOI: 10.1016/j.steroids.2015.05.008
  • Peer Reviewed / Open Access
• [Journal Article] GERMLINE DELETION OF ARMC5 IN FAMILIAL PRIMARY MACRONODULAR ADRENAL HYPERPLASIA. (2015)
  • Author(s): Suzuki S, Tatsuno I, Oohara E, Nakayama A, Komai E, Shiga A, Kono T, Takiguchi T, Higuchi S, Sakuma I, Nagano H, Hashimoto N, Mayama T, Koide H, Sasano H, Nakatani Y, Imamoto T, Ichikawa T, Yokote K, Tanaka T.
  • Journal Title: Endocr Pract. Volume: 21 Issue: 10 Pages: 1152-60
  • DOI: 10.4158/ep15756.or
  • Peer Reviewed / Open Access
• [Journal Article] PROGRESS IN PRIMARY ALDOSTERONISM:Is there a role for segmental adrenal venous sampling and adrenal sparing surgery in patients with primary aldosteronism? (2015)
  • Author(s): Satoh F, Morimoto R, Seiji K, Satani N, Ota H, Iwakura Y, Ono Y, Kud, M, Nezu M, Omata K, Tezuka Y, Kawasaki Y, Ishidoya S, Arai Y, Takase K, Nakamura Y, McNamara K, Sasano H, Ito S.
  • Journal Title: Eur J Endocrinol. Volume: 173(4) Issue: 4 Pages: 465-477
  • DOI: 10.1530/eje-14-1161
  • Peer Reviewed / Open Access
• [Journal Article] Sinonasal yolk sac (Endodermal sinus) tumor in an adult female - A case report and review of the literature. (2015)
  • Author(s): Mei X, Xia Y, Sasano H, Gao H.
  • Journal Title: APMIS. Volume: 123（9） Issue: 9 Pages: 810-814
  • DOI: 10.1111/apm.12409
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Prognostic significance of tumor-infiltrating CD8+ and FOXP3+ lymphocytes in residual tumors and alterations in these parameters after neoadjuvant chemotherapy in triple-negative breast cancer: a retrospective multicenter study. (2015)
  • Author(s): Miyashita M, Sasano H, Tamaki K, Hirakawa H, Takahashi Y, Nakagawa S, Watanabe G, Tada H, Suzuki A, Ohuchi N, Ishida T.
  • Journal Title: Breast Cancer Res. Volume: 17(1) Issue: 1 Pages: 124-124
  • DOI: 10.1186/s13058-015-0632-x
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] 11β-Prostaglandin F2α, a bioactive metabolite catalyzed by AKR1C3, stimulates Prostaglandin F receptor and induces Slug expression in breast cancer. (2015)
  • Author(s): Yoda T, Kikuchi K, Miki Y, Onodera Y, Hata S, Takagi K, Nakamura Y, Hirakawa H, Ishida T, Suzuki T, Ohuchi N, Sasano H, McNamara KM.
  • Journal Title: Mol Cell Endocrinol. Volume: 413 Pages: 236-247
  • DOI: 10.1016/j.mce.2015.07.008
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Surgical resection and chemoradiotherapy for metachronous pulmonary metastasis of basaloid squamous cell carcinoma of the oesophagus. (2015)
  • Author(s): Ishida H, Nakano T, Fujishima F, Kamei T, Taniyama Y, Sakurai T, Sato C, Fukutomi T, Kamiya K, Ozawa Y, Sasano H, Ohuchi N.
  • Journal Title: Int J Surg Case Rep. Volume: 17 Pages: 151-154
  • DOI: 10.1016/j.ijscr.2015.11.013
  • Peer Reviewed / Open Access
• [Journal Article] Aldosterone biosynthesis in the human adrenal cortex and associated disorders. (2015)
  • Author(s): Nakamura Y, Yamazaki Y, Konosu-Fukaya S, Ise K, Satoh F, Sasano H.
  • Journal Title: J Steroid Biochem Mol Biol. Volume: 153 Pages: 57-62
  • DOI: 10.1016/j.jsbmb.2015.05.008
  • Peer Reviewed / Open Access
• [Journal Article] Immunolocalization of thymidylate synthase as a favorable prognostic marker in estrogen receptor-positive breast carcinoma. (2015)
  • Author(s): Takagi K, Miki Y, Nakamura Y, Hirakawa H, Kakugawa Y, Amano G, Watanabe M, Ishida T, Sasano H, Suzuki T.
  • Journal Title: Histol Histopathol. Volume: 30（10） Pages: 1223-1232
  • Peer Reviewed
• [Journal Article] Pathology diagnosis of pancreatic neuroendocrine tumors. (2015)
  • Author(s): Kasajima, A. Yazdani, S. Sasano, H.
  • Journal Title: Journal of hepato-biliary-pancreatic sciences Volume: in press Issue: 8 Pages: 586-593
  • DOI: 10.1002/jhbp.208
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] KLF15 in breast cancer: a novel tumor suppressor? (2015)
  • Author(s): Yoda T, McNamara KM, Miki Y, Onodera Y, Takagi K, Nakamura Y, Ishida T, Suzuki T, Ohuchi N, Sasano H.
  • Journal Title: Cell Oncol (Dordr). Volume: 38（3） Issue: 3 Pages: 227-235
  • DOI: 10.1007/s13402-015-0226-8
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Pre-B Lymphocyte Protein 3 (VPREB3) Expression in the Adrenal Cortex:Precedent for non-Immunological Roles in Normal and Neoplastic Human Tissues. (2015)
  • Author(s): Felizola SJ, Katsu K, Ise K, Nakamura Y, Arai Y, Satoh F, Sasano H.
  • Journal Title: Endocr Pathol. Volume: 26（2） Issue: 2 Pages: 119-128
  • DOI: 10.1007/s12022-015-9366-7
  • Peer Reviewed / Open Access
• [Journal Article] Practical approaches for evaluating adrenal toxicity in nonclinical safety assessment. (2015)
  • Author(s): Inomata A, Sasano H.
  • Journal Title: J Toxicol Pathol. Volume: 28（3） Issue: 3 Pages: 125-132
  • DOI: 10.1293/tox.2015-0025
  • NAID: 130005090419
  • Peer Reviewed / Open Access
• [Journal Article] Hypoelectrolytic isoosmotic solution for infusion prevents saline-induced ultrastuructural artifacts of renal biopsy specimens (2015)
  • Author(s): Nakamura Y, McNamara KM, Onodera S, Kitamoto Y, Kisu K, Shibahara Y, Kurosu A, Sasano H, Sato H, Joh K
  • Journal Title: Pathol Int Volume: 65 Issue: 7 Pages: 374-378
  • DOI: 10.1111/pin.12302
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Adrenocortical Carcinoma: Review of the Pathologic Features, Production of Adrenal Steroids, and Molecular Pathogenesis. (2015)
  • Author(s): Nakamura Y, Yamazaki Y, Felizola SJ, Ise K, Morimoto R, Satoh F, Arai Y, Sasano H.
  • Journal Title: Endocrinol Metab Clin North Am. Volume: 44（2） Issue: 2 Pages: 399-410
  • DOI: 10.1016/j.ecl.2015.02.007
  • Peer Reviewed
• [Journal Article] 8D.02: PERIPHERAL PLASMA 18-OXOCORTISOL CAN DISCRIMINATE UNILATERAL ADENOMA FROM BILATERAL DISEASES IN PRIMARY ALDOSTERONISM PATIENTS. (2015)
  • Author(s): Satoh F, Morimoto R, Ono Y, Iwakura Y, Omata K, Kudo M, Tkase K, Seiji K, Gomez-Sanchez C, Rainey W, Nakamura Y, Sasano H, Ito S.
  • Journal Title: J Hypertens Volume: 33 Suppl 1 Issue: Supplement 1 Pages: e113-e113
  • DOI: 10.1097/01.hjh.0000467656.46285.fb
  • Peer Reviewed / Open Access
• [Journal Article] 8D.04: CLINICAL BENEFITS OF ADMINISTERING SUPER-SELECTIVE SEGMENTAL ADRENAL VENOUS SAMPLING AND PERFORMING ADRENAL SPARING SURGERY IN THE PATIENTS WITH PRIMARY ALDOSTERONISM. (2015)
  • Author(s): Satoh F, Morimoto R, Ono Y, Iwakura Y, Omata K, Kudo M, Satani N, Ota H, Seiji K, Takase K, Nakamura Y, Sasano H, Ito S.
  • Journal Title: J Hypertens. Volume: 33 Suppl 1 Issue: Supplement 1 Pages: e114-e114
  • DOI: 10.1097/01.hjh.0000467658.23414.b0
  • Peer Reviewed / Open Access
• [Journal Article] c-Met in esophageal squamous cell carcinoma: an independent prognostic factor and potential therapeutic target. (2015)
  • Author(s): Ozawa Y, Nakamura Y, Fujishima F, Felizola SJ, Takeda K, Okamoto H, Ito K, Ishida H, Konno T, Kamei T, Miyata G, Ohuchi N, Sasano H.
  • Journal Title: BMC Cancer. Volume: 15 Issue: 1 Pages: 451-451
  • DOI: 10.1186/s12885-015-1450-3
  • Peer Reviewed / Open Access
• [Journal Article] Modified autonomic regulation in mice mutated in the ß4 subunit of the lh/lh calcium channel. (2015)
  • Author(s): Murakami M, Suzuki T, Wu TW, Kuwasako K, Takahashi E, Watanabe H, Murakami AM, Miyoshi I, Yanagisawa T, Sasano H, Ono K, Ohba T
  • Journal Title: Biochem Biophys Res Commun Volume: pii: S0006-291X(15) Issue: 2 Pages: 200-205
  • DOI: 10.1016/j.bbrc.2015.03.112
  • Peer Reviewed / Open Access
• [Journal Article] Progesterone Receptor Isoforms A and B in Pancreatic Neuroendocrine Tumor (2015)
  • Author(s): Yazdani, S. Kasajima, A. Ogata, H. Felizola, S. J. Nakamura, Y. Onodera, Y. Motoi, F. Unno, M. Watanabe, M. Sasano, H.
  • Journal Title: Neuroendocrinology Volume: in press Issue: 4 Pages: 309-320
  • DOI: 10.1159/000381455
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Measurement of Peripheral Plasma 18-Oxo-cortisol Can Discriminate Uni-lateral Adenoma From Bilateral Diseases in Patients With Primary Aldosteronism (2015)
  • Author(s): F. Satoh, R. Morimoto, Y. Ono, Y. Iwakura, K Omata, M. Kudo, K. Takase, K. Seiji, H. Sasamoto, S. Honma, M. Okuyama, K. Yamashita, CE.Gomez-Sanchez, WE. Rainey, Y. Arai, H. Sasano, Y. Nakamura, S. Ito
  • Journal Title: Hypertension Volume: 65 Issue: 5 Pages: 1096-1102
  • DOI: 10.1161/hypertensionaha.114.04453
  • Peer Reviewed / Open Access
• [Journal Article] Anterior gradient 2 is correlated with EGFR mutation in lung adenocarcinoma tissues. (2015)
  • Author(s): Narumi S, Miki Y, Hata S, Ebina M, Saito M, Mori K, Kobayashi M, Suzuki T, Iwabuchi E, Sato I, Maemondo M, Endo C, Inoue A, Kondo T, Yamada-Okabe H, Ichinose M, Sasano H.
  • Journal Title: Int J Biol Markers. Volume: 30(2) Issue: 2 Pages: 234-242
  • DOI: 10.5301/jbm.5000131
  • Peer Reviewed
• [Journal Article] Androgen receptor and enzymes in lymph node metastasis and cancer reoccurrence in triple-negative breast cancer. (2015)
  • Author(s): McNamara KM, Yoda T, Miki Y, Nakamura Y, Suzuki T, Nemoto N, Miyashita M, Nishimura R, Arima N, Tamaki K, Ishida T, Ohuchi N, Sasano H.
  • Journal Title: Int J Biol Markers Volume: Epub ahead of print Issue: 2 Pages: 184-189
  • DOI: 10.5301/jbm.5000132
  • Peer Reviewed
• [Journal Article] G-cell hyperplasia of the stomach induces ECL-cell proliferation in the pyloric glands in a paracrinal manner (2015)
  • Author(s): Kasajima, A. Fujishima, F. Morikawa, T. Kawasaki, S. Konosu-Fukaya, S. Shibahara, Y. Nakamura, T. Yoshikawa, T. Iijima, K. Koike, T. Watanabe, M. Shibata, C. Sasano, H.
  • Journal Title: Pathology International Volume: 65 Issue: 5 Pages: 259-63
  • DOI: 10.1111/pin.12276
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Personalization of loco-regional care for primary breast cancer patients (part 1). (2015)
  • Author(s): Toi M, Winer EP, Benson JR, Inamoto T, Forbes JF, von Minckwitz G, Robertson JF, Grobmyer SR, Jatoi I, Sasano H, Kunkler I, Ho AY, Yamauchi C, Chow LW, Huang CS, Han W, Noguchi S, Pegram MD, Yamauchi H, Lee ES, Larionov AA, Bevilacqua JL, Yoshimura M, Sugie T, Yamauchi A, Krop IE, Noh DY, Klimberg VS.
  • Journal Title: Future Oncol. Volume: 11（9） Issue: 9 Pages: 1297-1300
  • DOI: 10.2217/fon.15.65
  • Peer Reviewed / Open Access
• [Journal Article] Personalization of loco-regional care for primary breast cancer patients (part 2). (2015)
  • Author(s): Toi M, Winer EP, Benson JR, Inamoto T, Forbes JF, von Minckwitz G, Robertson JF, Grobmyer SR, Jatoi I, Sasano H, Kunkler I, Ho AY, Yamauchi C, Chow LW, Huang CS, Han W, Noguchi S, Pegram MD, Yamauchi H, Lee ES, Larionov AA, Bevilacqua JL, Yoshimura M, Sugie T, Yamauchi A, Krop IE, Noh DY, Klimberg VS.
  • Journal Title: Future Oncol. Volume: 11（9） Issue: 9 Pages: 1301-1305
  • DOI: 10.2217/fon.15.66
  • Peer Reviewed / Open Access
• [Journal Article] Precise Preoperative Localization of Prostate Cancer Employing 12-Core Needle Biopsy with a Tissue-Marking Method for Effective Surgical Strategy (2015)
  • Author(s): Sato S, Watanabe M, Taniuchi S, Kasajima A, Mitsuzuka K, Nakamura Y, Fujishima F, Arai Y, Sasano H.
  • Journal Title: The Tohoku Journal of Experimental Medicine Volume: 236 Issue: 1 Pages: 55-61
  • DOI: 10.1620/tjem.236.55
  • NAID: 130005069563
  • ISSN: 0040-8727, 1349-3329
  • Peer Reviewed / Open Access
• [Journal Article] Clinical significance of subtype classification in metastatic lymph nodes of breast cancer patients undergoing neoadjuvant chemotherapy. (2015)
  • Author(s): Nemoto N1, Shibahara Y, Tada H, Uchida K, McNamara KM, Chan MS, Watanabe M, Tamaki K, Miyashita M, Miki Y, Gonda K, Ishida T, Ohuchi N, Sasano H.
  • Journal Title: Int J Biol Markers. Volume: in press Issue: 2 Pages: 174-183
  • DOI: 10.5301/jbm.5000128
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Decreased Expression of ARID1A Contributes to Infiltrative Growth of Esophageal Squamous Cell Carcinoma (2015)
  • Author(s): Ozawa Y, Nakamura Y, Fujishima F, Felizola SJ, Takeda K, Okamoto H, Ito K, Ishida H, Konno T, Kamei T, Ohuchi N, Sasano H.
  • Journal Title: The Tohoku Journal of Experimental Medicine Volume: 235 Issue: 3 Pages: 185-191
  • DOI: 10.1620/tjem.235.185
  • NAID: 130004822443
  • ISSN: 0040-8727, 1349-3329
  • Peer Reviewed / Open Access
• [Journal Article] Murine double minute 2 predicts response of advanced esophageal squamous cell carcinoma to definitive chemoradiotherapy. (2015)
  • Author(s): Okamoto H, Fujishima F, Kamei T, Nakamura Y, Ozawa Y, Miyata G, Nakano T, Katsura K, Abe S, Taniyama Y, Sakurai T, Teshima J, Hikage M, Sasano H, Ohuchi N.
  • Journal Title: BMC Cancer. Volume: 15 Issue: 1 Pages: 208-208
  • DOI: 10.1186/s12885-015-1222-0
  • Peer Reviewed / Open Access
• [Journal Article] 18F-FDG-PET-positive adrenal tumour (2015)
  • Author(s): Maiko Kakita-Kobayashi,Takeshi Usui,Hironobu Sasano,Akira Shimatsu
  • Journal Title: BMJ Case Reports Volume: 2015 Pages: 1-1
  • DOI: 10.1136/bcr-2015-209379
  • Peer Reviewed / Open Access
• [Journal Article] OX40 ligand expressed in glioblastoma modulates adaptive immunity depending on the microenvironment: a clue for successful immunotherapy. (2015)
  • Author(s): Shibahara I, Saito R, Zhang R, Chonan M, Shoji T, Kanamori M, Sonoda Y, Kumabe T, Kanehira M, Kikuchi T, So T, Watanabe T, Takahashi H, Iwabuchi E, Tanaka Y, Shibahara Y, Sasano H, Ishii N, Tominaga T.
  • Journal Title: Mol Cancer. Volume: 14（1） Issue: 1 Pages: 41-41
  • DOI: 10.1186/s12943-015-0307-3
  • NAID: 120006847260
  • Peer Reviewed / Open Access
• [Journal Article] The significance of combined CK5/6 and p63 immunohistochemistry in predicting the risks of subsequent carcinoma development in intraductal papilloma of the breast. (2015)
  • Author(s): Yang Y, Suzuki K, Abe E, Li C, Uno M, Akiyama F, Yamauchi H, Kikuchi M, Ohde S, Deshpande G, Shibahara Y, Nakamura Y, Sasano H.
  • Journal Title: Pathol Int. Volume: 65(2) Issue: 2 Pages: 81-88
  • DOI: 10.1111/pin.12248
  • Peer Reviewed / Open Access
• [Journal Article] Inhibits p53 in Human Breast Adipose Stromal Cells: A Novel Mechanism for the Regulation of Aromatase in Obesity and Breast Cancer. (2015)
  • Author(s): Wang X, Docanto MM, Sasano H.
  • Journal Title: Cancer Res. Volume: 75(4) Issue: 4 Pages: 645-655
  • DOI: 10.1158/0008-5472.can-14-2164
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A case of Cushing&rsquo;s syndrome due to bilateral cortisol-secreting adenomas with unilateral DHEAS oversecretion (2015)
  • Author(s): Monno S, Tachikawa T, Maekawa T, Sasano H.
  • Journal Title: Endocrine Journal Volume: 62 Issue: 3 Pages: 283-288
  • DOI: 10.1507/endocrj.EJ14-0552
  • NAID: 130005060857
  • ISSN: 0918-8959, 1348-4540
  • Peer Reviewed / Open Access
• [Journal Article] 3ß-hydroxysteroid dehydrogenase isoforms in human aldosterone-producing adenoma (2015)
  • Author(s): Konosu-Fukaya S, Nakamura Y, Satoh F, Ono Y, Felizola SJ, Ise K, Maekawa T, Takeda K, Katsu K, Fujishima F, Kasajima A, Watanabe M, Arai Y, Gomez-Sanchez EP, Gomez-Sanchez CE, Doi M, Okamura H, and Sasano H
  • Journal Title: Mol. Cell. Endocrinol. Volume: 印刷中 Pages: 205-212
  • DOI: 10.1016/j.mce.2014.10.008
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Presentation] Examination of steroid signatures in breast cancer and their association with traditional classifications (2017)
  • Author(s): Keely May McNamara, Ju-Yeon Moon, Hironobu Sasano, Man-Ho Choi
  • Organizer: The 2017 Japan-NIH Joint Symposium on Advances in Biomedical Research and Disease
  • Place of Presentation: Seiryo Auditorium(Tohoku University,Sendai Japan)
  • Year and Date: 2017-02-15
  • Int'l Joint Research
• [Presentation] Involvement of orphan nuclear receptor COUP-TFII in development of therapeutic resistance to erlotinib in non-small cell lung carcinoma (2017)
  • Author(s): Samaneh Yazdani, Yasuhiro Miki, Shuko Hata, Hironobu Sasano
  • Organizer: The 2017 Japan-NIH Joint Symposium on Advances in Biomedical Research and Disease
  • Place of Presentation: Seiryo Auditorium(Tohoku University,Sendai Japan)
  • Year and Date: 2017-02-15
  • Int'l Joint Research
• [Presentation] OLFM4 immunolocalization in breast carcinoma as a potent prognostic predictor (2017)
  • Author(s): Akifumi Mayama, Hiroyoshi Suzuki, Kiyoshi Takagi, Yoshiaki Onodera, Yasuhiro Miki, Takanori Watanabe, Kazuhiro Sakamoto, Ryuichi Yoshida, Takanori Ishida, Hironobu Sasano, Takashi Suzuki
  • Organizer: The 2017 Japan-NIH Joint Symposium on Advances in Biomedical Research and Disease
  • Place of Presentation: Seiryo Auditorium(Tohoku University,Sendai Japan)
  • Year and Date: 2017-02-15
  • Int'l Joint Research
• [Presentation] Significance of the androgen receptor in triple negative breast cancer patients treated with neoadjuvant chemotherapy (2017)
  • Author(s): Freeha Khalid, Fouzia Guestini, Keely May McNamara, Hironobu Sasano
  • Organizer: The 2017 Japan-NIH Joint Symposium on Advances in Biomedical Research and Disease
  • Place of Presentation: Seiryo Auditorium(Tohoku University,Sendai Japan)
  • Year and Date: 2017-02-15
  • Int'l Joint Research
• [Presentation] 偶発腫瘍を契機に診断されたアンドロゲン産生副腎腫瘍の１例 (2017)
  • Author(s): 森本玲、祢津昌広、手塚雄太、小野美澄、五十嵐康宏、工藤正孝、高瀬圭、宮城重人、亀井尚、山﨑有人、笹野公伸、伊藤貞嘉、佐藤文俊
  • Organizer: 第22回特定非営利活動法人東北内分泌研究会/第34回日本内分泌学会東北地方会
• [Presentation] コルチゾール産生性副腎皮質腺腫内の炎症細胞浸潤についての検討 (2017)
  • Author(s): 和泉健大龍、北脇優子、笹野公伸
  • Organizer: 第22回特定非営利活動法人東北内分泌研究会/第34回日本内分泌学会東北地方会
• [Presentation] 両側副腎摘除から7年後に局所再発、転移性肝腫瘍を認めた多発性内分泌腫瘍症2B型の1例 (2017)
  • Author(s): 手塚雄太、森本玲、祢津昌広、小野美澄、五十嵐康宏、工藤正孝、高瀬圭、宮城重人、山﨑有人、笹野公伸、伊藤貞嘉、佐藤文俊
  • Organizer: 第22回特定非営利活動法人東北内分泌研究会/第34回日本内分泌学会東北地方会
• [Presentation] アルドステロン産生腺腫におけるintratumoral heterogeneityの形態学的、免疫組織化学的画像解析 (2017)
  • Author(s): 東いぶき、宍戸悠華、尾股慧、小野美澄、山﨑有人、手塚雄太、森本玲、William E. Rainey、Scott A. Tomlins、中村保宏、伊藤貞嘉、佐藤文俊、笹野公伸
  • Organizer: 第22回特定非営利活動法人東北内分泌研究会/第34回日本内分泌学会東北地方会
• [Presentation] KCNJ5変異陽性のアルドステロン産生腺腫の臨床的、病理組織学的特徴 (2017)
  • Author(s): 宍戸悠華、東いぶき、尾股慧、小野美澄、山﨑有人、手塚雄太、森本玲、William E. Rainey、Scott A. Tomlins、中村保宏、伊藤貞嘉、佐藤文俊、笹野公伸
  • Organizer: 第22回特定非営利活動法人東北内分泌研究会/第34回日本内分泌学会東北地方会
• [Presentation] 副腎術後に重症心不全の改善を認めた原発性アルドステロン症の1例 (2017)
  • Author(s): 森本玲、小野美澄、祢津昌広、手塚雄太、五十嵐康宏、工藤正孝、鈴木秀明、下川宏明、高瀬圭、荒井陽一、山﨑有人、笹野公伸、伊藤貞嘉、佐藤文俊
  • Organizer: 第22回特定非営利活動法人東北内分泌研究会/第34回日本内分泌学会東北地方会
• [Presentation] 次世代シークエンサーによる原発性アルドステロン症の病態解明 (2017)
  • Author(s): 尾股慧、森本玲、手塚雄太、山﨑有人、中村保宏、ダニエルホベルソン、リウチアジェン、佐藤文俊、伊藤貞嘉、笹野公伸、スコットトムリンス、ウィリアムレイニー
  • Organizer: 第90回日本内分泌学会学術総会
• [Presentation] 副腎静脈サンプリングの診断基準に関する検討 (2017)
  • Author(s): 桐山加奈子、大村昌夫、齋藤淳、杉澤千穂、鶴谷悠也、山﨑有人、笹野公伸、西川哲男
  • Organizer: 第90回日本内分泌学会学術総会
• [Presentation] アルドステロン産生腺腫における18-oxocortisol合成の意義 (2017)
  • Author(s): 手塚雄太、中村保宏、北田容章、祢津昌広、小野美澄、岩倉芳倫、森本玲、工藤正孝、清治和将、高瀬圭、荒井陽一、伊勢和恵、山﨑有人、伊藤貞嘉、出澤真理、笹野公伸、佐藤文俊
  • Organizer: 第90回日本内分泌学会学術総会
• [Presentation] リング状石灰化を伴う副腎腫瘍2症例の検討 (2017)
  • Author(s): 伊藤裕進、能宗伸輔、馬場谷成、廣峰義久、庭野史丸、池田守、川畑由美子、笹野公伸、池上博司
  • Organizer: 第90回日本内分泌学会学術総会
• [Presentation] 術前副腎癌が疑われた、black adenomaによるサブクリニカルクッシング症例群の1例 (2017)
  • Author(s): 前田一成、戸邉駿一、柴田博絵、三澤晴雄、河崎さつき、田村泰、吉村一良、吉田利夫、山﨑有人、笹野公伸
  • Organizer: 第90回日本内分泌学会学術総会
• [Presentation] AVSで片側病変と判定されたが、術後の内分泌学的改善がなかった原発性アルドステロン症の一例 (2017)
  • Author(s): 五十嵐佳那、方波見卓行、浅井志高、福田尚志、川名部新、相田芳夫、山田隆之、笹野公伸、山﨑有人、田中逸
  • Organizer: 第90回日本内分泌学会学術総会
• [Presentation] 一腫瘍内に境界を画したFDGとMIBGの集積が確認された副腎皮質癌の一例 (2017)
  • Author(s): 綿貫裕、高安忍、水尻諭、大高英之、浅利ゆう子、木村裕輝、中田有紀、対馬悠子、蔭山和則、笹野公伸、大門眞
  • Organizer: 第90回日本内分泌学会学術総会
• [Presentation] 増大する左後腹膜腫瘍の1例 (2017)
  • Author(s): 手塚雄太、北脇優子、祢津昌広、五十嵐康宏、工藤正孝、森本玲、荒井陽一、笹野公伸、伊藤貞嘉、佐藤文俊
  • Organizer: 第23回特定非営利活動法人東北内分泌研究会/第35回日本内分泌学会東北地方会
• [Presentation] 原発性アルドステロン症の精査過程でABI低値を認めた1例 (2017)
  • Author(s): 森本玲、手塚雄太、祢津昌広、五十嵐康宏、工藤正孝、清治和将、高瀬圭、齋木佳克、笹野公伸、伊藤貞嘉、佐藤文俊
  • Organizer: 第23回特定非営利活動法人東北内分泌研究会/第35回日本内分泌学会東北地方会
• [Presentation] 副腎性 subclinical Cushing 症候群に対側アルドステロン過剰産生を合併した1例に対する免疫組織学的検討 (2017)
  • Author(s): 浅野嵩博、青野大輔、武田仁裕、米谷充弘、唐島成宙、出村昌史、臼倉幹哉、林研至、山岸正和、笹野公伸、米田隆、武田仁勇
  • Organizer: 第40回日本高血圧学会総会
• [Presentation] 原発巣手術から16年後に診断に至った悪性傍神経節腫の一例 (2017)
  • Author(s): 手塚雄太、祢津昌広、森本玲、工藤正孝、五十嵐康宏、山﨑有人、笹野公伸、伊藤貞嘉、佐藤文俊
  • Organizer: 第40回日本高血圧学会総会
• [Presentation] 副腎静脈サンプリングの pitfall によって片側副腎摘出を行った multiple adrenocortical micronodules (MN) による原発性アルドステロン症の1例 (2017)
  • Author(s): 和田典男、木村輔、臼淵浩明、寺江聡、田中博、関利盛、山﨑有人、笹野公伸
  • Organizer: 第40回日本高血圧学会総会
• [Presentation] 非機能性副腎腫瘍を合併した特発性アルドステロン症（IHA）の一例 (2017)
  • Author(s): 櫻井華奈子、山下りか、新妻さつき、佐藤良太、中村保宏、笹野公伸、在原善英
  • Organizer: 第40回日本高血圧学会総会
• [Presentation] 副腎静脈サンプリングで機能性を確認しえたアルドステロン産生腺腫合併の無症候性褐色細胞腫 (2017)
  • Author(s): 佐久間一基、山﨑有人、笹野公伸、横手幸太郎、田中知明
  • Organizer: 第40回日本高血圧学会総会
• [Presentation] アルドステロン産生腺腫における形態学的・免疫組織化学的・遺伝学的intratumor heterogeneityの検討 (2017)
  • Author(s): 宍戸悠華、東いぶき、尾股慧、小野美澄、山﨑有人、手塚雄太、森本玲、William E. Rainey、Scott A. Tomlins、中村保宏、伊藤貞嘉、笹野公伸、佐藤文俊
  • Organizer: 第21回日本臨床内分泌病理学会学術総会
• [Presentation] アルドステロン産生腺腫における病理組織学的定量解析 (2017)
  • Author(s): 東いぶき、宍戸悠華、尾股慧、小野美澄、山﨑有人、手塚雄太、森本玲、William E. Rainey、Scott A. Tomlins、中村保宏、伊藤貞嘉、佐藤文俊、笹野公伸
  • Organizer: 第21回日本臨床内分泌病理学会学術総会
• [Presentation] 潜在性コルチゾール分泌をともなったアルドステロン産生腺腫の一例 (2017)
  • Author(s): 松下真弥、田辺晶代、堀江沙良、高橋信行、宮崎秀幹、猪狩亨、山﨑有人、笹野公伸、梶尾裕
  • Organizer: 第21回日本臨床内分泌病理学会学術総会
• [Presentation] Myxoid variants of adrenal cancerの一例 (2017)
  • Author(s): 佐々木要輔、方波見卓行、中村祐太、石井聡、浅井志高、遠藤陽、高木正之、笹野公伸、田中逸
  • Organizer: 第21回日本臨床内分泌病理学会学術総会
• [Presentation] 肝腫瘍との鑑別を要した副腎皮質癌の一例 (2017)
  • Author(s): 立木美香、廣嶋佳歩、馬越洋宜、田上哲也、島津章、猪飼伊和夫、森吉弘毅、方波見卓行、笹野公伸、成瀬光栄
  • Organizer: 第21回日本臨床内分泌病理学会学術総会
• [Presentation] 初発時と再発時にカテコラミン産生能の差異を認めた悪性傍神経節腫の一例 (2017)
  • Author(s): 手塚雄太、山﨑有人、森本玲、祢津昌広、工藤正孝、五十嵐康宏、高瀬圭、宮城重人、伊藤貞嘉、笹野公伸、佐藤文俊
  • Organizer: 第21回日本臨床内分泌病理学会学術総会
• [Presentation] カテコラミン心筋症を呈した褐色細胞種の一剖検例 (2017)
  • Author(s): 井上千裕、山﨑有人、手塚雄太、祢津昌広、森本玲、佐藤文俊、笹野公伸
  • Organizer: 第21回日本臨床内分泌病理学会学術総会
• [Presentation] KCNJ5体細胞変異から見た原発性アルドステロン症の新分類 (2017)
  • Author(s): 笹野公伸、山﨑有人、尾股慧、小野美澄、手塚雄太、森本玲、中村保宏、伊藤貞嘉、佐藤文俊
  • Organizer: 第21回日本臨床内分泌病理学会学術総会
• [Presentation] 新規アルドステロン・レニン濃度迅速測定法による高血圧診療アセスメント (2017)
  • Author(s): 佐藤文俊、森本玲、小野美澄、手塚雄太、尾股慧、祢津昌広、岩倉芳倫、五十嵐康宏、工藤正孝、笹野公伸、伊藤貞嘉
  • Organizer: 第21回日本臨床内分泌病理学会学術総会
• [Presentation] 副腎腫瘍を合併し片側副腎摘出を行った両側性原発性アルドステロン症の2症例 (2017)
  • Author(s): 和田典男、柴山惟、宮野有希恵、小原慎司、山﨑有人、笹野公伸
  • Organizer: 第25回日本ステロイドホルモン学会学術集会
• [Presentation] EDP-M療法投与後、メトロノミック療法を施行した副腎皮質癌の1例 (2017)
  • Author(s): 月山秀一、方波見卓行、山本雄太郎、山﨑有人、笹野公伸、廣嶋佳歩、立木美香、成瀬光栄、北谷真子、五味弘道、西根亜実、村上万里子、浅井志高、福田尚志、田中逸
  • Organizer: 第27回臨床内分泌代謝Update
• [Presentation] 副脾、副副腎との鑑別に苦慮したCushing症候群の1例 (2017)
  • Author(s): 桜井華奈子、山下りか、新妻さつき、佐藤良太、力丸裕哉、齋藤英郎、中村保宏、笹野公伸
  • Organizer: 第27回臨床内分泌代謝Update
• [Presentation] MIBGシンチ陽性で診断に苦慮した副腎皮質オンコサイトーマの1例 (2017)
  • Author(s): 吉田健一、慕忻桐、原田万祐子、前田ゆき、阿部泰尚、前田浩志、上田佳世、山﨑有人、笹野公伸、梶川道子
  • Organizer: 第27回臨床内分泌代謝Update
• [Presentation] アンドロゲン産生副腎皮質腫瘍による思春期早発症の男児2例 (2017)
  • Author(s): 橘真紀子、三善陽子、和田珠希、福岡智哉、里村宜紀、保田紀恵、木村武司、長谷川泰浩、別所一彦、高間勇一、田附裕子、奥山宏臣、山﨑有人、笹野公伸、大薗恵一
  • Organizer: 第27回臨床内分泌代謝Update
• [Presentation] 尿中メタネフリンが上昇していた副腎外傍神経節腫の三症例 (2017)
  • Author(s): 鷲田啓資、高安忍、牧田興志、杉山綾、綿貫裕、照井健、大門眞、山﨑有人、笹野公伸
  • Organizer: 第27回臨床内分泌代謝Update
• [Presentation] UMNによるアルドステロン過剰分泌を合併したAIMAHの一例 (2017)
  • Author(s): 雪本真代、藏城雅文、待場優里、都井律和、永田友貴、山田真介、徳本真央、小野田尚佳、山﨑有人、笹野公伸、今西康雄、稲葉雅章
  • Organizer: 第27回臨床内分泌代謝Update
• [Presentation] 免疫組織でandrogen産生過剰が証明された副腎網状層過形成の一例 (2017)
  • Author(s): 渡邉貴子、佐野麻美、樋渡大、山﨑有人、笹野公伸、西井裕
  • Organizer: 第27回臨床内分泌代謝Update
• [Presentation] 原発性アルドステロン症を合併した副腎領域schwannomaの１例 (2017)
  • Author(s): 幕谷由佳子、馬場谷成、能宗伸輔、廣峰義久、伊藤裕進、武友保憲、山﨑有人、笹野公伸、川畑由美子、池上博司
  • Organizer: 第27回臨床内分泌代謝Update
• [Presentation] Aldosterone-Producing Adenoma Hidden behind Chronic Renal Failure with Nephrotic Syndrome. (2017)
  • Author(s): Yuta Tezuka, Ryo Morimoto, Yoshikiyo Ono, Yoshitsugu Iwakura, Masataka Kudo, Yasuhiro Igarashi, Mariko Miyazaki, Hiroshi Sato, Kazumasa Seiji, Kei Takase, Yoichi Arai, Yuto Yamazaki, Yasuhiro Nakamura, Hironobu Sasano, Sadayoshi Ito, Fumitoshi Satoh.
  • Organizer: ENDO2017
  • Int'l Joint Research
• [Presentation] Coexistence of Five Histopathologically and Genetically Distinct Adrenocortical Adenomas in a Patient with Primary Aldosteronism. (2017)
  • Author(s): Kei Omata, Yuto Yamazaki, Yasuhiro Nakamura, Sharath Anand, Justine Barletta, Scott A Tomlins, Hironobu Sasano, William E. Rainey,Anand Vaidya.
  • Organizer: ENDO2017
  • Int'l Joint Research
• [Presentation] Expression of Salt-Inducible Kinase (SIK) Isoforms in Human Adrenal Glands with Hyperaldosteronism. (2017)
  • Author(s): Yuto Yamazaki, Yasuhiro Nakamura, Miyuki Mukai, Kazue Ise, Kei Omata, Yoshikiyo Ono, Yuta Tezuka, Ryo Morimoto, Fumitoshi Satoh, Hironobu Sasano.
  • Organizer: ENDO2017
  • Int'l Joint Research
• [Presentation] The Expression of Androgen and Glucocorticoid Pathways in Normal Breast Tissue and the Impact of BMI on These Pathways. (2017)
  • Author(s): Keely M McNamara, Ayako Kanai, Hironobu Sasano, Kristy A Brown.
  • Organizer: ENDO2017
  • Int'l Joint Research
• [Presentation] The Significance of Inflammatory Cell Infiltration in Cortisol-Producing Adrenocortical Adenomas (CPA): A Possible Insight into Its Involvement in Pathogenesis of CPA. (2017)
  • Author(s): Yuko Kitawaki, Yasuhiro Nakamura, Fumie Kubota-Nakayama, Yuto Yamazaki, Shuko Hata, Kazue Ise, Ryo Morimoto, Kumi Kikuchi, Fumitoshi Satoh, Hironobu Sasano.
  • Organizer: ENDO2017
  • Int'l Joint Research
• [Presentation] OR10-2 Aldosterone-Producing Cell Clusters (APCC) Frequently Harbor Somatic Mutations and Accumulate with Age in Normal Adrenals. (2017)
  • Author(s): Kei Omata, Sharath Anand, Daniel H Hovelson, Chia-Jen Liu, Yuto Yamazaki, Yasuhiro Nakamura, Fumitoshi Satoh, Sadayoshi Ito, Hironobu Sasano, William E. Rainey, Scott A Tomlins.
  • Organizer: ENDO2017
  • Int'l Joint Research
• [Presentation] Endocrine pathology: Neroendocrine tumor in 2017 WHO classification. (2017)
  • Author(s): Hironobu Sasano
  • Organizer: The 57th IAP Thailand Annual Meeting
  • Int'l Joint Research / Invited
• [Presentation] From Endocrinology to Intracrinology. (2017)
  • Author(s): Hironobu Sasano
  • Organizer: Tohoku University-KIST joint symposium
  • Int'l Joint Research / Invited
• [Presentation] 肺がんおよび消化管神経内分泌膵臓の神経内分泌腫瘍との間の差 (2016)
  • Author(s): Hironobu Sasano
  • Organizer: 22nd Congress of Chinese Society of Pathology and 6th Annual Meeting of Chinese Pathologists
  • Place of Presentation: Hefei (China)
  • Year and Date: 2016-11-24
  • Int'l Joint Research
• [Presentation] 顕性クッシング症候群が拡張型心筋症の原因と考えられた1例 (2016)
  • Author(s): 月山秀一、方波見卓行、福田尚志、浅井志高、松葉怜、五十嵐佳那、川名部新、相田芳夫、松田央郎、明石嘉浩、山﨑有人、笹野公伸、田中逸
  • Organizer: 第26回臨床内分泌代謝Update
  • Place of Presentation: 大宮ソニックシティ（埼玉）
  • Year and Date: 2016-11-18
• [Presentation] アルドステロン・コルチゾール同時産生副腎皮質癌の1例 (2016)
  • Author(s): 古家美菜絵、小野正人、井上浩輔、杉澤千穂、鶴谷悠也、齋藤淳、大村昌夫、長谷川直樹、角田幸雄、宮崎紳一郎、山﨑有人、笹野公伸、西川哲男
  • Organizer: 第26回臨床内分泌代謝Update
  • Place of Presentation: 大宮ソニックシティ（埼玉）
  • Year and Date: 2016-11-18
• [Presentation] 透析中の血圧管理に難渋した副腎内傍神経節腫合併血液透析症例 (2016)
  • Author(s): 手塚雄太、森本玲、秋保真穂、藤倉恵美、祢津昌広、小野美澄、五十嵐康宏、工藤正孝、高瀬圭、荒井陽一、山﨑有人、笹野公伸、伊藤貞嘉、佐藤文俊
  • Organizer: 第26回臨床内分泌代謝Update
  • Place of Presentation: 大宮ソニックシティ（埼玉）
  • Year and Date: 2016-11-18
• [Presentation] 両側副腎腺腫からのcortisol分泌過剰を認めたCushing症候群の1例 (2016)
  • Author(s): 出口ハンナ、吉田知彦、大野友寛、山﨑有人、笹野公伸、山本恭平、寺野隆
  • Organizer: 第26回臨床内分泌代謝Update
  • Place of Presentation: 大宮ソニックシティ（埼玉）
  • Year and Date: 2016-11-18
• [Presentation] 腹膜神経鞘腫を合併したサブクリニカルクッシング症候群の1例 (2016)
  • Author(s): 戸邊駿一、柴田博絵、三澤晴雄、河崎さつき、田村泰、山﨑有人、笹野公伸
  • Organizer: 第26回臨床内分泌代謝Update
  • Place of Presentation: 大宮ソニックシティ（埼玉）
  • Year and Date: 2016-11-18
• [Presentation] 対照的臨床像を示した新規VHL遺伝子変異を伴う家族性褐色細胞腫 (2016)
  • Author(s): 天神歩美、方波見卓行、石井聡、浅井志高、相田芳夫、臼井健、山﨑有人、笹野公伸、田中逸
  • Organizer: 第26回臨床内分泌代謝Update
  • Place of Presentation: 大宮ソニックシティ（埼玉）
  • Year and Date: 2016-11-18
• [Presentation] 副腎皮質癌12例の臨床的特徴と腫瘍組織を用いた予後予測因子解析 (2016)
  • Author(s): 志賀明菜、滝口朋子、中山哲俊、樋口誠一郎、佐久間一基、永野秀和、鈴木佐和子、 小出尚史、笹野公伸、田中知明、横手幸太郎
  • Organizer: 第26回臨床内分泌代謝Update
  • Place of Presentation: 大宮ソニックシティ（埼玉）
  • Year and Date: 2016-11-18
• [Presentation] Diagnosis and treatment of adrenocortical carcinomas, an update (2016)
  • Author(s): Hironobu Sasano
  • Organizer: XXXI International Congress of the IAP and 28th Congress of the ESP
  • Place of Presentation: Cologne (Germany)
  • Year and Date: 2016-09-25
  • Int'l Joint Research / Invited
• [Presentation] 副腎皮質癌の病理診断の新しい展開：WHO Endocrine Tumor 2017に向けて (2016)
  • Author(s): 笹野公伸
  • Organizer: 第20回日本内分泌病理学会学術総会
  • Place of Presentation: 東京コンベンションホール（東京）
  • Year and Date: 2016-09-16
  • Invited
• [Presentation] コルチゾール自律産生性副腎皮質腺腫内における炎症細胞浸潤とその背景についての検討 (2016)
  • Author(s): 北脇優子、中村保宏、久保田文恵、山崎有人、端秀子、伊勢和恵、菊池久美、森本玲、佐藤文俊、笹野公伸
  • Organizer: 第20回日本内分泌病理学会学術総会
  • Place of Presentation: 東京コンベンションホール（東京）
  • Year and Date: 2016-09-16
• [Presentation] 腫瘍増大および潜在的コルチゾール過剰分泌が疑われ副腎癌との鑑別に苦慮した副腎海綿 状血管腫(疑い)の一例 (2016)
  • Author(s): 高橋信行、田辺晶代、菊池智彦、辻本哲郎、中條大輔、飯塚俊彦、山田大介、久米春喜、笹野公伸、春日雅人、梶尾裕
  • Organizer: 第20回日本内分泌病理学会学術総会
  • Place of Presentation: 東京コンベンションホール（東京）
  • Year and Date: 2016-09-16
• [Presentation] RNAシークエンスとメチル化解析からとらえた異所性ACTH産生褐色細胞腫の分子機構 (2016)
  • Author(s): 佐久間一基、藤本真徳、樋口誠一郎、駒井絵里、鈴木佐和子、横手幸太郎、小野克彦、笹野公伸、田中知明
  • Organizer: 第20回日本内分泌病理学会学術総会
  • Place of Presentation: 東京コンベンションホール（東京）
  • Year and Date: 2016-09-16
• [Presentation] microAPAにおけるCa2+channel発現動態の解析 (2016)
  • Author(s): 小森和磨、山﨑有人、伊勢和恵、手塚雄太、尾股慧、小野美澄、森本玲、中村保宏、佐藤文俊、笹野公伸
  • Organizer: 第20回日本内分泌病理学会学術総会
  • Place of Presentation: 東京コンベンションホール（東京）
  • Year and Date: 2016-09-16
• [Presentation] 片側副腎摘出後も内分泌的改善が得られなかった原発性アルドステロン症の一例 (2016)
  • Author(s): 五十嵐佳那、方波見卓行、浅井志高、福田尚志、川名部新、相田芳夫、笹野公伸、山﨑有人、田中逸
  • Organizer: 第20回日本内分泌病理学会学術総会
  • Place of Presentation: 東京コンベンションホール（東京）
  • Year and Date: 2016-09-16
• [Presentation] 後腹膜Schwannomaを合併し片側副腎摘出を行った両側性原発性アルドステロン症の1例 (2016)
  • Author(s): 柴山惟、和田典男、高橋明裕、菅原基、小原慎司、秋元真祐子、辻隆裕、深澤雄一郎、山﨑有人、笹野公伸
  • Organizer: 第20回日本内分泌病理学会学術総会
  • Place of Presentation: 東京コンベンションホール（東京）
  • Year and Date: 2016-09-16
• [Presentation] 原発性アルドステロン症を伴ったエストロゲン産生副腎皮質腺腫の一例 (2016)
  • Author(s): 手塚雄太、山﨑有人、森本玲、北脇優子、中村保宏、小野美澄、岩倉芳倫、工藤正孝、尾股慧、祢津昌広、五十嵐康宏、清治和将、高瀬圭、荒井陽一、伊藤貞嘉、笹野公伸、佐藤文俊
  • Organizer: 第20回日本内分泌病理学会学術総会
  • Place of Presentation: 東京コンベンションホール（東京）
  • Year and Date: 2016-09-16
• [Presentation] 乳癌の進歩と病理学的研究 (2016)
  • Author(s): Hironobu Sasano
  • Organizer: seminar of Breast Diagnostic Pathology
  • Place of Presentation: Suzhu (China)
  • Year and Date: 2016-08-26
  • Int'l Joint Research / Invited
• [Presentation] 子宮内膜癌組織におけるコルチゾールによるaromataseの誘導 (2016)
  • Author(s): 三木康宏、笛未崎、髙木清司、鈴木貴、笹野公伸、伊藤潔
  • Organizer: 第17回ホルモンと癌研究会
  • Place of Presentation: 倉敷アイビースクエア（岡山）
  • Year and Date: 2016-06-24
• [Presentation] エストロゲン受容体陰性乳癌におけるCancer-associated fibroblasts(CAFs)由来因子 によるアンドロゲン合成酵素の発現誘導 (2016)
  • Author(s): 菊地杏子、McNamara M Keely、三木康宏、櫻井美奈子、小野寺好明、笹野公伸
  • Organizer: 第17回ホルモンと癌研究会
  • Place of Presentation: 倉敷アイビースクエア（岡山）
  • Year and Date: 2016-06-24
• [Presentation] 乳癌微小環境における27-hydroxycholesterolを介した癌細胞と脂肪細胞の相互作用 (2016)
  • Author(s): 櫻井美奈子、石際康平、三木康宏、高木清司、鈴木貴、笹野公伸
  • Organizer: 第17回ホルモンと癌研究会
  • Place of Presentation: 倉敷アイビースクエア（岡山）
  • Year and Date: 2016-06-24
• [Presentation] 乳癌アロマターゼ阻害剤治療中の関節痛改善を目的とした看護介入ランダム化比較試験 (2016)
  • Author(s): 長嶺沙野香、高江洲睦代、玉城研太朗、鎌田義彦、上原協、照喜名重治、新垣美羽、玉津陽子、山城和子、宮下穣、石田孝宣、大内憲明、笹野公伸、玉城信光
  • Organizer: 第24回日本乳癌学会学術総会
  • Place of Presentation: 東京ビッグサイト（東京）
  • Year and Date: 2016-06-16
• [Presentation] 乳がん周術期におけるアロマセラピーのQOL 効果を検討したランダム化比較試験 (2016)
  • Author(s): 小松亜紀子、玉城研太朗、鎌田義彦、上原協、山城和子、新垣美羽、玉津陽子、石田孝宣、宮下穣、大内憲明、笹野公伸、玉城信光
  • Organizer: 第24回日本乳癌学会学術総会
  • Place of Presentation: 東京ビッグサイト（東京）
  • Year and Date: 2016-06-16
• [Presentation] Molecular pathology update of adrenocortical neoplasms in 2016 (2016)
  • Author(s): Hironobu Sasano
  • Organizer: DGPatho16_Invitation to the 100th Annual Meeting of the German Society of Pathology
  • Place of Presentation: Berlin (Germany)
  • Year and Date: 2016-05-19
  • Int'l Joint Research / Invited
• [Presentation] 副腎皮質腫瘍の病理組織鑑別診断のポイント：臨床への報告／確認事項 (2016)
  • Author(s): 笹野公伸
  • Organizer: 第105回日本病理学会総会
  • Place of Presentation: 仙台国際センター（宮城）
  • Year and Date: 2016-05-12
  • Invited
• [Presentation] The roles of 27-hydroxycholesterol synthesizing enzyme, CYP27A1 in breast tumor micoenvironment (2016)
  • Author(s): 櫻井美奈子、三木康宏、高木清司、鈴木貴、石田孝宜、大内憲明、笹野公伸
  • Organizer: 第105回日本病理学会総会
  • Place of Presentation: 仙台国際センター（宮城）
  • Year and Date: 2016-05-12
• [Presentation] 超解像顕微鏡を用いたエストロゲン受容体発現局在の解析 (2016)
  • Author(s): 岩渕英里奈、三木康宏、小野克彦、小野寺好明、笹野公伸
  • Organizer: 第105回日本病理学会総会
  • Place of Presentation: 仙台国際センター（宮城）
  • Year and Date: 2016-05-12
• [Presentation] 原発性アルドステロン症の新しい病理組織学的分類 (2016)
  • Author(s): 山﨑有人、中村保宏、伊勢和恵、北脇優子、久保田文恵、手塚雄太、尾股慧、森本玲、佐藤文俊、笹野公伸
  • Organizer: 第105回日本病理学会総会
  • Place of Presentation: 仙台国際センター（宮城）
  • Year and Date: 2016-05-12
• [Presentation] 副腎oncocytomaの1例 (2016)
  • Author(s): 伊藤以知郎、斎木寛、山﨑有人、角田優子、中島孝、庭川要、笹野公伸
  • Organizer: 第105回日本病理学会総会
  • Place of Presentation: 仙台国際センター（宮城）
  • Year and Date: 2016-05-12
• [Presentation] コルチゾール自律産生性副腎皮質腺腫における炎症性細胞浸潤とその誘因についての 病理学的検討 (2016)
  • Author(s): 北脇優子、中村保宏、久保田文恵、山﨑有人、端秀子、伊勢和恵、菊池久美、森本玲、佐藤文俊、笹野公伸
  • Organizer: 第105回日本病理学会総会
  • Place of Presentation: 仙台国際センター（宮城）
  • Year and Date: 2016-05-12
• [Presentation] 副腎皮質腺腫内に発生した副腎皮質癌の1例 (2016)
  • Author(s): 清水亜衣、岩崎沙理、小熊昴、鈴木信、今雅史、池田仁、山﨑有人、松野吉宏、笹野公伸、鈴木昭
  • Organizer: 第105回日本病理学会総会
  • Place of Presentation: 仙台国際センター（宮城）
  • Year and Date: 2016-05-12
• [Presentation] ヒト副腎皮質腫瘍におけるSalt-inducible kinase isoformの発現解析 (2016)
  • Author(s): 向美祐希、山﨑有人、伊勢和恵、北脇優子、手塚雄太、小野美澄、森本玲、佐藤文俊、中村保宏、笹野公伸
  • Organizer: 第105回日本病理学会総会
  • Place of Presentation: 仙台国際センター（宮城）
  • Year and Date: 2016-05-12
• [Presentation] 剖検における多重癌症例の病理組織学的検討 (2016)
  • Author(s): 東野江里、柴原裕紀子、高橋裕明、楊陽、三木康宏、鈴木高祐、笹野公伸
  • Organizer: 第105回日本病理学会総会
  • Place of Presentation: 仙台国際センター（宮城）
  • Year and Date: 2016-05-12
• [Presentation] 肥満／エストロゲン／乳癌：乳癌患者で何故適切な体重維持が重要か？ (2016)
  • Author(s): 笹野公伸
  • Organizer: 第89回日本内分泌学会学術総会
  • Place of Presentation: 国立京都国際会館（京都）
  • Year and Date: 2016-04-21
  • Invited
• [Presentation] New Development in Pathology of Primary Aldosteronism : What Endocrine Surgeon Should Know in 2016 (2016)
  • Author(s): Hironobu Sasano
  • Organizer: 15th Congress of the Asian Association of Endocrine Surgeons
  • Place of Presentation: Seoul (Korea)
  • Year and Date: 2016-04-07
  • Int'l Joint Research / Invited
• [Presentation] Effect of Intratumoral Cortisol on Aromatase Expression in Cancer Stromal Cells of Endometrial Carcinoma (2016)
  • Author(s): Yasuhiro Miki, Misaki Fue, Kiyoshi Takagi, Takashi Suzuki, Hironobu Sasano, Kiyoshi Ito
  • Organizer: ENDO2016
  • Place of Presentation: Boston (USA)
  • Year and Date: 2016-04-01
  • Int'l Joint Research
• [Presentation] Sex Steroid Signatures in Frozen Tissue Sections May Reveal Intratumoral Metabolism of Breast Cancer (2016)
  • Author(s): Ju-Yeon Moon, Keely M McNamara, Jung-Jin Lee, Bong Chul Chung, Hironobu Sasano, Man-Ho Choi
  • Organizer: ENDO2016
  • Place of Presentation: Boston (USA)
  • Year and Date: 2016-04-01
  • Int'l Joint Research
• [Presentation] Roles of Steroid Receptors and Regulators of Estrogen Bio-Synthesizing Enzymes in Erlotinib Resistant Lung Carcinoma Cell Line PC9 (2016)
  • Author(s): Samaneh Yazdani, Yasuhiro Miki, Shuko Hata, Hironobu Sasano
  • Organizer: ENDO2016
  • Place of Presentation: Boston (USA)
  • Year and Date: 2016-04-01
  • Int'l Joint Research
• [Presentation] Germline Deletion of ARMC5 in Familial Primary Macronodular Adrenal Hyperplasia (2016)
  • Author(s): Yuki Taki, Sawako Suzuki, Takashi Kono, Akitoshi Nakayama, Hidekazu Nagano, Ichiro Tatsuno, Hironobu Sasano, Koutaro Yokote, Tomoaki Tanaka
  • Organizer: ENDO2016
  • Place of Presentation: Boston (USA)
  • Year and Date: 2016-04-01
  • Int'l Joint Research
• [Presentation] New Histological Classification of Primary Aldosteronism ～CYP11B2 Localization in CT Negative PA～ (2016)
  • Author(s): Yuto Yamazaki, Yasuhiro Nakamura, Kazue Ise1, Kei Omata, Yoshikiyo Ono, Yuta Tezuka, Ryo Morimoto, Fumitoshi Satoh, Hironobu Sasano
  • Organizer: ENDO2016
  • Place of Presentation: Boston (USA)
  • Year and Date: 2016-04-01
  • Int'l Joint Research
• [Presentation] Dissecting the Molecular Pathways of Primary Aldosteronism (2016)
  • Author(s): Hironobu Sasano
  • Organizer: ENDO2016
  • Place of Presentation: Boston (USA)
  • Year and Date: 2016-04-01
  • Int'l Joint Research / Invited
• [Presentation] Hypomethylation of the Pomc Promoter in ACTH Producing Pheochromocytoma (2016)
  • Author(s): Ikki Sakuma, Seiichirou Higuchi, Masanori Fujimoto, Tomoko Takiguchi, Akitoshi Nakayama, Ai Tamura, Takashi Kohno, Eri Komai, Akina Shiga, Hidekazu Nagano, Naoko Hashimoto, Sawako Suzuki, Takafumi Mayama, Hisashi Koide, Katsuhiko Ono, Hironobu Sasano, Ichiro Tatsuno, Koutaro Yokote, Tomoaki Tanaka
  • Organizer: ENDO2016
  • Place of Presentation: Boston (USA)
  • Year and Date: 2016-04-01
  • Int'l Joint Research
• [Presentation] Methylation Status of Vitamin D Receptor Gene Promoter in Benign and Malignant Adrenal Tumors (2016)
  • Author(s): Catia Pilon, Andrea Rebellato, Riccardo Urbanet, Vincenza Guzzardo, Rocco Cappellesso, Hironobu Sasano, Ambrogio Fassina, Francesco Fallo
  • Organizer: ENDO2016
  • Place of Presentation: Boston (USA)
  • Year and Date: 2016-04-01
  • Int'l Joint Research
• [Presentation] Novel ARMC5 Alterations in Japanese Primary Macronodular Adrenal Hyperplasia Patients (2016)
  • Author(s): Sawako Suzuki, Yuki Taki1, Takashi Kono, Akitoshi Nakayama, Ichiro Tatsuno, Hironobu Sasano, Koutaro Yokote, Tomoaki Tanaka
  • Organizer: ENDO2016
  • Place of Presentation: Boston (USA)
  • Year and Date: 2016-04-01
  • Int'l Joint Research
• [Presentation] Aldosterone-Producing Cell Clusters Accumulate with Age in Normal Adrenal Glands (2016)
  • Author(s): Kei Omata, Daniel H. Hovelson, Chia-Jen Liu, Fumitoshi Satoh, Hironobu Sasano, William E. Rainey, Scott A Tomlins
  • Organizer: ENDO2016
  • Place of Presentation: Boston (USA)
  • Year and Date: 2016-04-01
  • Int'l Joint Research
• [Presentation] Pilot Study of Glucocorticoid Metabolism in Triple Negative Breast Cancers (TNBC) (2016)
  • Author(s): Keely M McNamara, Tiffany Mori, Minoru Miyashita, Noriko Nemoto, Kentaro Tamaki, Takanori Ishida, Noriaki Ohuchi, Hironobu Sasano
  • Organizer: ENDO2016
  • Place of Presentation: Boston (USA)
  • Year and Date: 2016-04-01
  • Int'l Joint Research
• [Presentation] A Case of Cardiac Myxoma and Subclinical Cushing's Syndrome Associated with a Novel Mutation in Fumarate Hydratase (FH) Gene and the Significance of Mutation in FH Gene in Adrenal Tumors (2016)
  • Author(s): Kentaro Suda, Hidenori Fukuoka, Miki Mukai, Katsuhiko Ono, Genzo Iguchi, Yukiko Odake, Kenichi Yoshida, Ryusaku Matsumoto, Hironori Bando, Hitoshi Nishizawa, Michiko Takahashi, Hironobu Sasano, Wataru Ogawa, Yutaka Takahashi
  • Organizer: ENDO2016
  • Place of Presentation: Boston (USA)
  • Year and Date: 2016-04-01
  • Int'l Joint Research
• [Presentation] New Innovative Rapid Assay of Plasma Aldosteorne Concentration and Active Renin Concentration Are Effective for Diagnosing Primary Aldosteronism (2016)
  • Author(s): Yoshikiyo Ono, Ryo Morimoto, Yuta Tezuka, Kei Omata, Masahiro Nezu, Yasuhiro Igarashi, Yoshitsugu Iwakura, Masataka Kudo, Kazumasa Seiji, Kei Takase, Yuto Yamazaki, Yasuhiro Nakamura, Hironobu Sasano, Sadayoshi Ito, Fumitoshi Satoh
  • Organizer: ENDO2016
  • Place of Presentation: Boston (USA)
  • Year and Date: 2016-04-01
  • Int'l Joint Research
• [Presentation] NOVEL CLASSIFICATION OF NEOPLASTIC AND NON-NEOPLASTIC PRIMARY ALDOSTERONISM (2016)
  • Author(s): Hironobu Sasano
  • Organizer: 41st International Aldosterone Conference
  • Place of Presentation: ボストン（アメリカ合衆国)
  • Year and Date: 2016-03-30
  • Int'l Joint Research
• [Presentation] ヒト副腎皮質 (2016)
  • Author(s): 笹野公伸
  • Organizer: 第23回日本ステロイドホルモン学会学術集会
  • Place of Presentation: 倉敷市芸文館（岡山県倉敷市）
  • Year and Date: 2016-01-15
• [Presentation] 副腎内傍神経節腫の外科治療により血糖・血圧のコントロールが改善した血液透析患者の 一例 (2016)
  • Author(s): 秋保真穂、佐藤浩司、手塚雄太、祢津昌広、小野美澄、五十嵐康宏、森本玲、工藤正孝、吉田舞、藤倉恵美、山本多恵、宮崎真理子、荒井陽一、笹野公伸、伊藤貞嘉、佐藤文俊
  • Organizer: 第21回特定非営利活動法人東北内分泌研究会/第33回日本内分泌学会東北地方会
  • Place of Presentation: 山形国際ホテル（山形）
• [Presentation] 腎硬化症に伴う二次性アルドステロン症を合併したアルドステロン産生腺腫の一例 (2016)
  • Author(s): 手塚雄太、島田佐登志、秋保真穂、小野美澄、岩倉芳倫、森本玲、工藤正孝、五十嵐康宏、清治和将、高瀬圭、荒井陽一、山﨑有人、笹野公伸、宮崎真理子、伊藤貞嘉、佐藤文俊
  • Organizer: 第21回特定非営利活動法人東北内分泌研究会/第33回日本内分泌学会東北地方会
  • Place of Presentation: 山形国際ホテル（山形）
• [Presentation] 副腎悪性腫瘍の新しい展開：ＷＨＯ２０１６を踏まえて (2016)
  • Author(s): 笹野公伸
  • Organizer: 第16回日本内分泌学会東海支部学術集会
  • Place of Presentation: アクトシティ―浜松コングレスセンター（静岡）
  • Invited
• [Presentation] Aldosterone producing cell clusters (APCCs) precursors of PA (2016)
  • Author(s): Hironobu Sasano
  • Organizer: The Second Symposium of the Korean Adrenal Gland and Endocrine Hypertension Study Group
  • Place of Presentation: Seoul (Korea)
  • Int'l Joint Research / Invited
• [Presentation] Obesity, Estrogen and Breast cancer: Exploring missing links among Triad (2016)
  • Author(s): Hironobu Sasano
  • Organizer: special seminar at Chulalongkorn University
  • Place of Presentation: Bangkok (Thai)
  • Int'l Joint Research / Invited
• [Presentation] 123I-MIBG Scintigram-Negative Functioning Pheochromocytoma Associated with Low Expression of Norepinephrine Transporters: A Case Report (2016)
  • Author(s): Kazuma Ogiso, Nobuyuki Koriyama, Taisei Ijuin, Tomoko Takiguchi, Ikki Sakuma, Hironobu Sasano, Yoshihiko Nishio, Tomoaki Tanaka
  • Organizer: ENDO2016
  • Place of Presentation: Boston (USA)
  • Int'l Joint Research
• [Presentation] A Potential Role of Endogenous SERM, 27-Hydroxy Cholesterol Synthesizing Enzyme, CYP27A1 in Breast Tumor Microenvironment (2016)
  • Author(s): Minako Sakurai, Yasuhiro Miki, Kiyoshi Takagi, Takashi Suzuki,Hironobu Sasano
  • Organizer: ENDO2016
  • Place of Presentation: Boston (USA)
  • Int'l Joint Research
• [Presentation] Estrogen, Obesity and Breast Cance (2015)
  • Author(s): Hironobu Sasano
  • Organizer: 2015 ANNUAL Carol M. Baldwin Breast Cancer Research Lecture
  • Place of Presentation: シラキュース（アメリカ合衆国)
  • Year and Date: 2015-12-03
  • Int'l Joint Research
• [Presentation] 原発性アルドステロン症における組織学的新分類の提唱 (2015)
  • Author(s): 山﨑有人、中村保宏、伊勢和恵、尾股慧、小野美澄、森本玲、佐藤文俊
  • Organizer: 第19回特定非営利活動法人東北内分泌研究会/第31回日本内分泌学会東北地方会
  • Place of Presentation: リンクモア平安閣市民ホール（青森県青森市）
  • Year and Date: 2015-10-31
• [Presentation] アルドステロン産生腺腫におけるmicroRNAの網羅的発現解析：KCNJ5体細胞変異との関連性の検討 (2015)
  • Author(s): 山﨑有人、中村保宏、菊池久美、端秀子、伊勢和恵、森本玲、佐藤文俊、笹野公伸
  • Organizer: 第19回日本内分泌病理学会学術総会
  • Place of Presentation: アバンセ（佐賀県佐賀市）
  • Year and Date: 2015-10-24
• [Presentation] 副腎皮質癌の治療標的因子 (2015)
  • Author(s): 笹野公伸
  • Organizer: 第27回日本内分泌外科学会総会
  • Place of Presentation: アバンセ（佐賀県佐賀市）
  • Year and Date: 2015-10-24
• [Presentation] アルドステロン過剰の副腎皮質球状層は過形成から腫瘍へ移行するのか？ (2015)
  • Author(s): 笹野公伸、中村保宏、尾股慧、北脇優子、小野美澄、山﨑有人、佐藤文俊
  • Organizer: 第19回日本内分泌病理学会学術総会
  • Place of Presentation: アバンセ（佐賀県佐賀市）
  • Year and Date: 2015-10-24
• [Presentation] Pathology of CT negative primary aldosteronism at post B2 era (2015)
  • Author(s): Hironobu Sasano
  • Organizer: tumor board
  • Place of Presentation: アナーバー（アメリカ合衆国)
  • Year and Date: 2015-10-13
  • Invited
• [Presentation] 副腎性高血圧の病理update (2015)
  • Author(s): 笹野公伸
  • Organizer: 第38回日本高血圧学会総会
  • Place of Presentation: 愛媛県県民文化会館（愛媛県松山市）
  • Year and Date: 2015-10-09
• [Presentation] Update on adrenal cortical tumours (2015)
  • Author(s): Hironobu Sasano
  • Organizer: The 9th Asia Pacific IAP Congress: APIAP 2015
  • Place of Presentation: ブリスベン（オーストラリア）
  • Year and Date: 2015-06-04
  • Int'l Joint Research
• [Presentation] 内分泌外科医が知っておくべきアルドステロン合成/分泌の新知見 (2015)
  • Author(s): 笹野公伸、中村保宏、山﨑有人、佐藤文俊
  • Organizer: 第27回日本内分泌外科学会総会
  • Place of Presentation: コラッセふくしま（福島県福島市）
  • Year and Date: 2015-05-28
• [Presentation] 副腎皮質癌の治療標的因子 (2015)
  • Author(s): 笹野公伸
  • Organizer: 第27回日本内分泌外科学会総会
  • Place of Presentation: コラッセふくしま（福島県福島市）
  • Year and Date: 2015-05-28
• [Presentation] Dissecting hormone production and secretion in primary aldosteronism (2015)
  • Author(s): Hironobu Sasano
  • Organizer: 2015 Seoul International Congress of Endocrinology and Metabolism in conjunction with - 34th Annual Meeting of Korean Endocrine Society
  • Place of Presentation: ソウル(韓国)
  • Year and Date: 2015-04-30
  • Int'l Joint Research
• [Presentation] 非外分泌腫瘍-神経内分泌腫瘍を中心に- (2015)
  • Author(s): 笠島敦子、藤島史喜、笹野公伸
  • Organizer: 第104回日本病理学会総会
  • Place of Presentation: 名古屋国際会議場（愛知県名古屋市）
  • Year and Date: 2015-04-30
• [Presentation] 副腎皮質癌におけるKi67標識率の解析：eye ball versus image analysis (2015)
  • Author(s): 山﨑有人、中村保宏、笠島敦子、藤島史喜、前川尚志、緑川早苗、沖隆、馬場聡、佐藤文俊、笹野公伸
  • Organizer: 第104回日本病理学会総会
  • Place of Presentation: 名古屋国際会議場（愛知県名古屋市）
  • Year and Date: 2015-04-30
• [Presentation] 副腎の内分泌病理学の臨床内分泌学への貢献 (2015)
  • Author(s): 笹野公伸
  • Organizer: 第88回日本内分泌学会学術総会
  • Place of Presentation: ホテルニューオータニ東京（東京都千代田区）
  • Year and Date: 2015-04-23