Identification and clinical application of diagnostic and therapeutic marker of esophageal and gastric cancer targeting cancer stem cell

• Project/Area Number: 15H04713
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Human pathology
• Research Institution: Hiroshima University
• Principal Investigator: YASUI WATARU 広島大学, 医歯薬保健学研究科(医), 教授 (40191118)
• Co-Investigator(Renkei-kenkyūsha): OUE NAOHIDE 広島大学, 大学院医歯薬保健学研究科, 准教授 (60346484) ; KUNIYASU HIROKI 奈良県立医科大学, 医学部, 教授 (00253055)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000); Fiscal Year 2017: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2016: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000); Fiscal Year 2015: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
• Keywords: 食道癌 / 胃癌 / 癌幹細胞 / CAST法 / 新規診断・治療標的 / Spheroid / KIFC1 / KIF23 / DSG1 / IQGAP3 / MCOLN3 / BST2

Outline of Final Research Achievements

As candidate diagnostic and therapeutic targets of esophageal and gastric cancers associated with spheroid-forming cancer stem cells, kinesin family (KIFC1, KIF11, KIF23), IQGAP3, DSG1 were identified. BST2 and MCOLN3, identified from 5-FU-resistant gastric cancer cells, were found to regulate chemosensitivity. These findings will contribute to the application to the diagnosis and treatment for therapy-resistant cancer stem cells.

Research Products

• [Journal Article] Overexpression of transmembrane protein BST2 induces phosphorylation of Akt and Erk in bladder cancer (2017)
  • Author(s): Shigematsu Y, Oue N, Nishioka Y, Sakamoto N, Sentani K, Sekino Y, Goto K, Teishima J, Matsubara A, Yasui W
  • Journal Title: Oncology Letters Volume: 14 Pages: 999-1004
  • Peer Reviewed / Open Access
• [Journal Article] The Expression of BTS-2 Enhances Cell Growth and Invasiveness in Renal Cell Carcinoma (2017)
  • Author(s): Pham QT, Oue N, Yamamoto Y, Shigematsu Y, Sekino Y, Sakamoto N, Sentani K, Uraoka N, Tiwari M, Yasui W
  • Journal Title: Anticancer Res Volume: 37 Pages: 2853-2860
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Overexpression of the Transmembrane Protein IQGAP3 Is Associated with Poor Survival of Patients with Gastric Cancer. (2017)
  • Author(s): Oue N, Yamamoto Y, Oshima T, Asai R, Ishikawa A, Uraoka N, Sakamoto N, Sentani K, Yasui W.
  • Journal Title: Pathobiology Volume: - Issue: 3 Pages: 192-200
  • DOI: 10.1159/000481890
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Overexpression of PCDHB9 promotes peritoneal metastasis and correlates with poor prognosis in patients with gastric cancer. (2017)
  • Author(s): Mukai S, Oue N, Oshima T, Imai T, Sekino Y, Honma R, Sakamoto N, Sentani K, Kuniyasu H, Egi H, Tanabe K, Yoshida K, Ohdan H, Yasui W.
  • Journal Title: J Pathol Volume: 243 Issue: 1 Pages: 100-110
  • DOI: 10.1002/path.4931
  • Peer Reviewed / Open Access
• [Journal Article] Silencing of Discoidin Domain Receptor-1 (DDR1) Concurrently Inhibits Multiple Steps of Metastasis Cascade in Gastric Cancer (2017)
  • Author(s): Yuge R, Kitadai Y, Takigawa H, Naito T, Oue N, Yasui W, Tanaka S, Chayama K
  • Journal Title: Transl Oncol Volume: 11 Issue: 3 Pages: 575-584
  • DOI: 10.1016/j.tranon.2018.02.003
  • Peer Reviewed / Open Access
• [Journal Article] SIX1 maintains tumor basal cells via TGF-β pathway and associates with poor prognosis in esophageal cancer (2017)
  • Author(s): Nishimura T, Tamaoki M, Komatsuzaki R, Oue N, Taniguchi H, Komatsu M, Aoyagi K, Minashi K, Chiwaki F, Shinohara H, Tachimori Y, Yasui W, Muto M, Yoshida T, Sakai Y, Sasaki H
  • Journal Title: Cancer Science Volume: 108 Issue: 2 Pages: 216-225
  • DOI: 10.1111/cas.13135
  • Peer Reviewed / Open Access
• [Journal Article] KIF11 is required for spheroid formation of oesophageal and colorectal cancers (2017)
  • Author(s): Imai T, Oue N, Sentani K, Sakamoto N, Uraoka N, Egi H, Hinoi T, Ohdan H, Yoshida K and Yasui W
  • Journal Title: Anticancer Res Volume: 37 Pages: 47-55
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] KIFC1 induces resistance to docetaxel and is associated with survival of prostate cancer patients (2017)
  • Author(s): Sekino Y, Oue N, Shigematsu Y, Ishikawa A, Sakamoto N, Sentani K, Teishima J, Matsubara A, Yasui W
  • Journal Title: Urologic Oncology Volume: 35 Issue: 1 Pages: 13-31
  • DOI: 10.1016/j.urolonc.2016.08.007
  • Peer Reviewed / Open Access
• [Journal Article] Overexpression of KIF11 in gastric cancer with intestinal mucin phenotype (2016)
  • Author(s): Imai T, Oue N, Nishioka M, Mukai S, Oshima T, Sakamoto N, Sentani K, Matsusaki K, Yoshida K, Yasui W
  • Journal Title: Pathobiology Volume: 84 Issue: 1 Pages: 16-24
  • DOI: 10.1159/000447303
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Induction of KIFC1 expression in gastric cancer spheroids (2016)
  • Author(s): Oue N, Mukai S, Imai T, Trang TBP, Oshima T, Sentani K, Sakamoto N, Yoshida K, Yasui W
  • Journal Title: Oncology Reports Volume: 36 Issue: 1 Pages: 349-355
  • DOI: 10.3892/or.2016.4781
  • Peer Reviewed / Open Access
• [Journal Article] Overexpression of transmembrane protein BST2, participating in cell growth, is associated with poor survival in patients with esophageal, gastric and colorectal cancer (2016)
  • Author(s): Mukai S, Oue N, Oshima T, Tatsumoto Y, Sakamoto N, Sentani N, Hinoi T, Ohdan H, Yasui W
  • Journal Title: Annals of Surgical Oncology Volume: 24 Issue: 2 Pages: 594-602
  • DOI: 10.1245/s10434-016-5100-z
  • Peer Reviewed / Open Access
• [Journal Article] Overexpression of transmembrane protein BST2, participating in cell growth, is associated with poor survival in patients with esophageal, gastric and colorectal cancer (2016)
  • Author(s): Mukai S, Oue N, Oshima T, Tatsumoto Y, Sakamoto N, Sentani N, Hinoi T, Ohdan H, Yasui W
  • Journal Title: Ann Surg Oncol Volume: 印刷中
  • Peer Reviewed / Open Access
• [Journal Article] Fukutin, identified by the Escherichia coli ampicillin secretion trap (CAST) method, participates in tumor progression in gastric cancer. (2016)
  • Author(s): Oo HZ, Sentani K, Mukai S, Hattori T, Shinmei S, Goto K, Sakamoto N, Naito Y, Anami K, Trang PT, Yanagihara K, Oue N, Yasui W.
  • Journal Title: Gastric Cancer Volume: 19 Issue: 2 Pages: 443-452
  • DOI: 10.1007/s10120-015-0511-2
  • NAID: 40020835493
  • Peer Reviewed / Open Access
• [Journal Article] The transcribed-ultra conserved regions in prostate and gastric cancer: DNA hypermethylation and microRNA-associated regulation. (2015)
  • Author(s): Keisuke Goto, Sho Ishikawa,Ririno Honma, Keiji Tanimoto, Naoya Sakamoto,Kazuhiro Sentani, Naohide Oue, Jun Teishima, Akio Matsubara and Wataru Yasui.
  • Journal Title: Oncogene Volume: 1 Issue: 27 Pages: 1-1
  • DOI: 10.1038/onc.2015.445
  • Peer Reviewed / Open Access
• [Journal Article] TSPAN8, identified by Escherichia coli ampicillin secretion trap, is associated with cell growth and invasion in gastric cancer (2015)
  • Author(s): Katsuhiro Anami, Naohide Oue, Tsuyoshi Noguchi, Naoya Sakamoto, Kazuhiro Sentani, Tetsutaro Hayashi, Yutaka Naito, Htoo Zarni Oo, Wataru Yasui
  • Journal Title: Gastric Cancer Volume: ahead of print Issue: 2 Pages: 370-380
  • DOI: 10.1007/s10120-015-0478-z
  • Peer Reviewed / Open Access
• [Journal Article] Clinicopathologic and molecular characteristics of gastric cancer showing gastric and intestinal mucin phenotype (2015)
  • Author(s): Oue N, Sentani K, Sakamoto N, Yasui W
  • Journal Title: Cancer Sci Volume: 106 Issue: 8 Pages: 951-958
  • DOI: 10.1111/cas.12706
  • Peer Reviewed / Open Access
• [Journal Article] New molecular staging with G-factor supplements TNM classification in gastric cancer: A multicenter collaborative research by the Japanese Society for Gastroenterological Carcinogenesis G-Project committee (2015)
  • Author(s): Sawada T, Yashiro M, Sentani K, Oue N, Yasui W, Miyazaki K, Kai K, Fushida S, Fujimura T, Ohira M, Kakeji Y, Natsugoe S, Shirabe K, Nomura S, Shimada Y, Tomita N, Hirakawa K, Maehara Y
  • Journal Title: Gastric Cancer Volume: 18 Issue: 1 Pages: 119-128
  • DOI: 10.1007/s10120-014-0338-2
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] TEM1 expression in cancer-associated fibroblasts is correlated with a poor prognosis in patients with gastric cancer. (2015)
  • Author(s): Fujii S, Fujihara A, Natori K, Abe A, Kuboki Y, Higuchi Y, Aizawa M, Kuwata T, Kinoshita T, Yasui W, Ochiai A.
  • Journal Title: Cancer Med. Volume: 4 Issue: 11 Pages: 1667-1678
  • DOI: 10.1002/cam4.515
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Presentation] Molecular pathology of gastric cancer in the past, present and future precision medicine (2017)
  • Author(s): Yasui W
  • Organizer: 第89回日本胃癌学会総会
  • Place of Presentation: 広島
  • Year and Date: 2017-03-08
  • Invited
• [Presentation] The value and challenge of HER2 pathways in gastric cancer therapy (2017)
  • Author(s): Yasui W, Oue N, Sentani K, Sakamoto N
  • Organizer: 12th International Gastric Cancer Congress
  • Int'l Joint Research / Invited
• [Presentation] Molecular pathology of cancer in the past, present and future precision medicine (2017)
  • Author(s): 安井 弥
  • Organizer: 第76回日本癌学会学術総会
  • Invited
• [Presentation] 胃癌の病理 －現状と展望－ (2017)
  • Author(s): 安井 弥
  • Organizer: 第55回日本癌治療学会学術集会
  • Invited
• [Presentation] 食道癌および大腸癌におけるKinesin family member 11の発現・機能解析 (2017)
  • Author(s): 今井健晴、山本悠司、大上直秀、坂本直也、仙谷和弘、吉田和弘、安井 弥.
  • Organizer: 第106回日本病理学会総会
• [Presentation] IQGAP3の発現誘導と胃癌におけるスフェロイド形成 (2017)
  • Author(s): 大上直秀、山本悠司、今井健晴、田邊和照、大段秀樹、坂本直也、仙谷和弘、安井 弥
  • Organizer: 第106回日本病理学会総会
• [Presentation] 膜蛋白質IQGAP3は胃癌の進行に関与する (2017)
  • Author(s): 大上直秀、今井健晴、山本悠司、坂本直也、仙谷和弘、安井 弥
  • Organizer: 第26回日本がん転移学会学術集会
• [Presentation] 腎癌におけるBST2の発現・機能解析 (2017)
  • Author(s): Pham Quoc Thang、関野陽平、大上直秀、重松慶紀、坂本直也、仙谷和弘、亭島 淳、松原昭郎、安井 弥
  • Organizer: 第26回日本がん転移学会学術集会
• [Presentation] 胃癌におけるKIF23の発現解析とスフェロイド形成への影響 (2017)
  • Author(s): 浅井竜一、今井健晴、山本悠司、大上直秀、仙谷和弘、坂本直也、吉田和弘、安井 弥
  • Organizer: 第14回日本病理学会カンファレンス
• [Presentation] 膀胱癌におけるKIF23の発現・機能解析 (2017)
  • Author(s): 重松慶紀、大上直秀、関野陽平、坂本直也、仙谷和弘、亭島 淳、松原昭郎、安井 弥
  • Organizer: 第76回日本癌学会学術総会
• [Presentation] BST-2の発現は増殖能・浸潤能に関係する (2017)
  • Author(s): Pham Quoc Thang、大上直秀、山本悠司、重松慶紀、関野陽平、坂本直也、仙谷和弘、浦岡直礼、Tiwari Mamata、安井 弥
  • Organizer: 第76回日本癌学会学術総会
• [Presentation] KIF23は食道癌・大腸癌細胞におけるスフェロイド形成に必要である (2017)
  • Author(s): 浅井竜一、大上直秀、今井健晴、山本悠司、福永武史、坂本直也、仙谷和弘、吉田和弘、安井 弥
  • Organizer: 第76回日本癌学会学術総会
• [Presentation] IQGAP3の発現は胃癌の予後不良と関連する (2017)
  • Author(s): 大上直秀、山本悠司、今井健晴、田邊和照、大段秀樹、坂本直也、仙谷和弘、安井 弥
  • Organizer: 第76回日本癌学会学術総会
• [Presentation] KIF23の発現は胃癌の予後と相関する (2017)
  • Author(s): 山本悠司、大上直秀、今井健晴、浅井竜一、坂本直也、仙谷和弘、大段秀樹、安井 弥
  • Organizer: 第76回日本癌学会学術総会
• [Presentation] IQGAPは胃癌の予後と相関する (2017)
  • Author(s): 大上直秀、山本悠司、田邊和照、大段秀樹、坂本直也、仙谷和弘、安井 弥
  • Organizer: 第28回日本消化器癌発生学会総会・第9回国際消化器癌発生会議
• [Presentation] Cross-disciplinary approach to control gastric cancer in precision medicine (2016)
  • Author(s): Yasui W
  • Organizer: The 2016 Annual Congress of Korean Surgical Society
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2016-11-03
  • Int'l Joint Research / Invited
• [Presentation] 食道扁平上皮癌におけるKIFC1の発現と幹細胞の関連 (2016)
  • Author(s): 服部 結、大上直秀、服部拓也、今井健晴、坂本直也、仙谷和弘、安井 弥
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 横浜
  • Year and Date: 2016-10-06
• [Presentation] 膀胱癌におけるBST2の発現・機能解析 (2016)
  • Author(s): 重松慶紀、大上直秀、関野陽平、向井正一朗、後藤景介、仙谷和弘、亭島 淳、松原昭郎、安井 弥
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 横浜
  • Year and Date: 2016-10-06
• [Presentation] 食道扁平上皮癌におけるKinesis family member11の発現解析 (2016)
  • Author(s): 石川 洸、今井健晴、向井正一朗、坂本直也、仙谷和弘、大上直秀、安井 弥
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 横浜
  • Year and Date: 2016-10-06
• [Presentation] KIF11は腸型胃癌の発生に関与する (2016)
  • Author(s): 今井健晴、大上直秀、向井正一朗、坂本直也、仙谷和弘、吉田和弘、安井 弥
  • Organizer: 第75回日本癌学会学術総会
  • Place of Presentation: 横浜
  • Year and Date: 2016-10-06
• [Presentation] 膜貫通蛋白質PCDHB9は接着及び播種を促進し胃癌の予後不良に関与する (2016)
  • Author(s): 大上直秀、向井正一朗、今井健晴、國安弘基、仙谷 和弘、坂本直也、大段秀樹、吉田和弘 、安井 弥
  • Organizer: 第27回日本消化器癌発生学会総会
  • Place of Presentation: 鹿児島
  • Year and Date: 2016-09-15
  • Invited
• [Presentation] Molecular pathological approach to develop novel cancer diagnostics and therapeutics (2016)
  • Author(s): Yasui W
  • Organizer: The 27th Annual Meeting of the Japanese Society of Oral Pathology
  • Place of Presentation: Hiroshima (Japan)
  • Year and Date: 2016-08-10
  • Int'l Joint Research / Invited
• [Presentation] Kinesin family member11の胃癌における発現・機能解析 (2016)
  • Author(s): 今井健晴、大上直秀、仙谷和弘、安井 弥
  • Organizer: 第25回日本がん転移学会学術集会
  • Place of Presentation: 米子
  • Year and Date: 2016-07-21
• [Presentation] Assessment and clinical application of markers for stratification of recurrence risk after curative resection of stage II/III gastric cancer (2016)
  • Author(s): Oshima T, Kimura Y, Sakamaki K, Miyagi Y, Yamanaka S, Oue N, Cho H, Yoshikawa T, Rino Y, Yasui W, Imada T, Masuda M
  • Organizer: The 2016 ASCO Annual Meeting
  • Place of Presentation: Illinois, Chicago (USA)
  • Year and Date: 2016-06-03
  • Int'l Joint Research
• [Presentation] 胃癌におけるKinesin family member11の発現・機能解析 (2016)
  • Author(s): 今井健晴、向井正一朗、大上直秀、仙谷和弘、吉田和弘、安井 弥
  • Organizer: 第105回日本病理学会総会
  • Place of Presentation: 仙台
  • Year and Date: 2016-05-12
• [Presentation] 胃癌におけるPCDHB9の機能および発現意義について (2016)
  • Author(s): 向井正一朗、大上直秀、後藤景介、仙谷和弘、大段秀樹、安井 弥
  • Organizer: 第105回日本病理学会総会
  • Place of Presentation: 仙台
  • Year and Date: 2016-05-12
• [Presentation] 胃癌に対する病理診断 (2016)
  • Author(s): 安井 弥
  • Organizer: Gastric Cancer Symposium in 中四国
  • Place of Presentation: 岡山
  • Year and Date: 2016-03-12
  • Invited
• [Presentation] 病理からみた胃癌とは？ (2016)
  • Author(s): 安井 弥
  • Organizer: Taiho Gastric Cancer Forum in West Japan-
  • Place of Presentation: 神戸
  • Year and Date: 2016-01-30
  • Invited
• [Presentation] KIF C1とKIF 11の胃癌における分子腫瘍マーカーとしての意義 (2016)
  • Author(s): 今井健晴、大上直秀、坂本直也、仙谷和弘、吉田和弘、安井 弥
  • Organizer: 第36回日本分子腫瘍マーカー研究会
  • Place of Presentation: 横浜
• [Presentation] 胃癌幹細胞およびスフェロイド形成におけるKIFC1の役割 (2015)
  • Author(s): 大上直秀、向井正一朗、今井健晴、T.B.Pham Trang、仙谷和弘、安井 弥
  • Organizer: 第26回日本消化器癌発生学会総会
  • Place of Presentation: 米子
  • Year and Date: 2015-11-19
• [Presentation] Molecular pathology of gastric cancer (2015)
  • Author(s): Yasui W
  • Organizer: The 2nd International Forum for Japan and Korea Medical Exchange
  • Place of Presentation: Kure, Japan
  • Year and Date: 2015-10-17
  • Int'l Joint Research / Invited
• [Presentation] 胃癌におけるPCDHB9の発現とその意義 (2015)
  • Author(s): 向井正一朗、大上直秀、後藤景介、仙谷和弘、大段秀樹、安井 弥
  • Organizer: 第74回日本癌学会学術総会
  • Place of Presentation: 名古屋
  • Year and Date: 2015-10-08
• [Presentation] KIFC1は胃癌細胞のスフェロイド形成に重要である (2015)
  • Author(s): 大上直秀、向井正一朗、Pham T.B Trang、仙谷和弘、安井 弥
  • Organizer: 第74回日本癌学会学術総会
  • Place of Presentation: 名古屋
  • Year and Date: 2015-10-08
• [Presentation] 食道扁平上皮癌におけるPCDHB9の機能解析 (2015)
  • Author(s): 今井健晴、向井正一朗、大上直秀、後藤景介、仙谷和弘、大段秀樹、吉田和弘、安井 弥
  • Organizer: 第74回日本癌学会学術総会
  • Place of Presentation: 名古屋
  • Year and Date: 2015-10-08
• [Presentation] 食道癌におけるBST2の発現 (2015)
  • Author(s): 服部 結、大上直秀、Htoo Zarni Oo、向井正一朗、仙谷和弘、大段秀樹、安井 弥
  • Organizer: 第74回日本癌学会学術総会
  • Place of Presentation: 名古屋
  • Year and Date: 2015-10-08
• [Presentation] SAGE法・CAST法から同定した胃癌関連マーカーとその意義 (2015)
  • Author(s): 大上直秀、仙谷和弘、坂本直也、浦岡直礼、服部拓也、安井 弥
  • Organizer: 第35回日本分子腫瘍マーカー研究会
  • Place of Presentation: 名古屋
  • Year and Date: 2015-10-07
  • Invited
• [Presentation] Molecular pathology of gastric cancer (2015)
  • Author(s): Yasui W
  • Organizer: JP Kim Memorial International Gastric Cancer Symposium
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2015-07-31
  • Int'l Joint Research / Invited
• [Presentation] 胃癌細胞のスフェロイド形成におけるKIFC1の役割 (2015)
  • Author(s): 大上直秀、向井正一朗、Pham T.B. Trang、坂本直也、仙谷和弘、安井 弥
  • Organizer: 第24回日本がん転移学会学術集会・総会
  • Place of Presentation: 大阪
  • Year and Date: 2015-07-23
• [Presentation] Endoscopic management of early gastric cancer: Molecular analysis in endoscopic specimen (2015)
  • Author(s): Yasui W
  • Organizer: The 11th International Gastric Cancer Congress
  • Place of Presentation: Sao Paulo, Brazil
  • Year and Date: 2015-06-04
  • Int'l Joint Research / Invited
• [Presentation] 胃癌におけるBST2発現は5-FU感受性と関連がある． (2015)
  • Author(s): 向井正一朗、大上直秀、仙谷和弘、Htoo Zarni Oo、大段秀樹、安井 弥
  • Organizer: 第104回日本病理学会総会
  • Place of Presentation: 名古屋
  • Year and Date: 2015-04-30
• [Presentation] CAST法を用いて同定したBST2の食道癌における機能解析 (2015)
  • Author(s): 立本淑子、向井正一朗、PhamThi Binh Trang、大上直秀、仙谷和弘、安井 弥
  • Organizer: 第104回日本病理学会総会
  • Place of Presentation: 名古屋
  • Year and Date: 2015-04-30
• [Presentation] 胃癌におけるスフェロイド形成関連遺伝子と癌幹細胞との関連 (2015)
  • Author(s): 大上直秀、向井正一朗、Pham T.B Trang、坂本直也、仙谷和弘、安井 弥
  • Organizer: 第104回日本病理学会総会
  • Place of Presentation: 名古屋
  • Year and Date: 2015-04-30
• [Presentation] 食道扁平上皮癌におけるolfactomedin4発現に関する分子病理学的検討 (2015)
  • Author(s): 浦岡直礼、大上直秀、仙谷和弘、向井正一朗、服部拓也、野口 剛、安井 弥
  • Organizer: 第104回日本病理学会総会
  • Place of Presentation: 名古屋
  • Year and Date: 2015-04-30
• [Presentation] Significance of KIFC1 in spheroid formation of gastric cancer cells. (2015)
  • Author(s): Oue N, Mukai S, Pham TBT, Sentani K, Yasui W
  • Organizer: AACR (American Association for Cancer Research) Annual Meeting 2015
  • Place of Presentation: Philadelphia, Pennsylvania (USA)
  • Year and Date: 2015-04-18
  • Int'l Joint Research
• [Remarks] 広島大学大学院分子病理学研究室
  • URL: http://home.hiroshima-u.ac.jp/byori1/
• [Remarks] 広島大学大学院分子病理学研究室ホームページ
  • URL: http://home.hiroshima-u.ac.jp/byori1/