| Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2019: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2018: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2017: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2016: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2015: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
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| Outline of Final Research Achievements |
The purpose of this study was to investigate a method for individual optimization of radiation therapy for patients with brain metastases. Through this research, a possibility was shown as follows; 1) the combined use of whole-brain radiation therapy (WBRT) with stereotactic irradiation (STI) may reduce the recurrence rate of brain tumors and improve the prognosis in a group of patients with an estimated prognosis of12 months or longer, 2) the cut-off value reflecting the clinically significant changes in neurocognitive function should be 1.5SD or higher in the international standardized neuro-cognitive battery, 3) the WBRT dose when combined with STI could be reduced from 30Gy-in-10 to 25Gy-in-10 without compromising brain tumor control and the reduction of dosage may improve the rate of preservation of neurocognitive function.
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