Development of comprehensive evaluation of local and systemic condition by skin blotting
| Project/Area Number |
15H05066
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Fundamental nursing
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| Research Institution | The University of Tokyo |
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Principal Investigator |
Minematsu Takeo 東京大学, 大学院医学系研究科(医学部), 特任准教授 (00398752)
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| Co-Investigator(Kenkyū-buntansha) |
禰屋 光男 びわこ成蹊スポーツ大学, スポーツ学部, 准教授 (30359640)
山田 実 筑波大学, 人間系, 准教授 (30525572)
吉田 美香子 東京大学, 大学院医学系研究科(医学部), 特任講師 (40382957)
真田 弘美 東京大学, 大学院医学系研究科(医学部), 教授 (50143920)
野口 博史 東京大学, 大学院医学系研究科(医学部), 特任講師 (50431797)
仲上 豪二朗 東京大学, 大学院医学系研究科(医学部), 准教授 (70547827)
玉井 奈緒 東京大学, 大学院医学系研究科(医学部), 特任講師 (80636788)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥15,470,000 (Direct Cost: ¥11,900,000、Indirect Cost: ¥3,570,000)
Fiscal Year 2017: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2016: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
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| Keywords | スキンアセスメント / スキンケア / スキンブロッティング / 掻痒症 / 脱水症 / 内部標準マーカー / 看護技術 |
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| Outline of Final Research Achievements |
To establish the comprehensive assessment of skin local condition and systemic condition by skin blotting method which noninvasively extracts soluble proteins from skin tissue, we conducted the animal experiments and clinical studies. These results indicated that albumin extraction depends on the skin barrier function, and internal standard markers to normalize the extraction efficiency in skin blotting. Albumin and Annexin A2 are the promising internal standard markers. Furthermore, it is reported that skin blotting detecting NGFb and taurine reflects to itching and dehydration in older people.
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Report
(4 results)
Research Products
(44 results)
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[Journal Article] Biofilm detection by wound blotting can predict slough development in pressure ulcers: a retrospective observational study.2017
Author(s)
Nakagami G, Schultz G, Gibson DJ, Phillips P, Kitamura A, Minematsu T, Miyagaki T, Hayashi A, Sasaki S, Sugama J, Sanada H.
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Journal Title
Wound Repair and Regeneration
Volume: 25
Issue: 1
Pages: 131-138
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Histopathology of incontinence-associated skin lesions: inner tissue damage due to invasion of proteolytic enzymes and bacteria in macerated rat skin.2015
Author(s)
Mugita Y, Minematsu T, Huang L, Nakagami G, Kishi C, Ichikawa Y, Nagase T, Oe M, Noguchi H, Mori T, Abe M, Sugama J, Sanada H.
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Journal Title
PLoS One
Volume: 10
Issue: 9
Pages: e0138117-e0138117
DOI
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Peer Reviewed / Open Access
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[Book] 看護理工学2015
Author(s)
真田弘美，森武俊
Total Pages
234
Publisher
東京大学出版会
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