Nursing Model for Lifestyle-related Disease Prevention: Based on the Results of a 20-year Large-scale Randomized Follow-up Study

• Project/Area Number: 15H05102
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Community health nursing
• Research Institution: Nagoya University
• Principal Investigator: Kajita Etsuko 名古屋大学, 医学系研究科(保健), 教授 (50135373)
• Co-Investigator(Kenkyū-buntansha): 中谷 芳美 福井県立大学, 看護福祉学部, 教授 (90217753) ; 玉置 淳子 大阪医科大学, 医学部, 教授 (90326356) ; 伊木 雅之 近畿大学, 医学部, 教授 (50184388)
• Co-Investigator(Renkei-kenkyūsha): WATAI Izumi 名古屋大学, 大学院医学系研究科, 准教授 (20509830) ; NAGAI Kuniyoshi 豊橋創造大学, 保健医療学部, 准教授 (70402625) ; ITO Naoko 名古屋大学, 大学院医学系研究科, 助教 (80456681)
• Research Collaborator: HAMADA Masami ; ARAI Kiyomi
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000); Fiscal Year 2017: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000); Fiscal Year 2016: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000); Fiscal Year 2015: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
• Keywords: 生活習慣病 / 追跡調査 / 指導指針 / 生活習慣病予防 / 保健指導

Outline of Final Research Achievements

To measure lifestyle and physical factors associated with osteoporosis and other lifestyle-related diseases, and develop guidelines for the provision of health guidance as a preventive measure against them, a long-term longitudinal study was conducted, involving 2,039 randomly selected residents of 5 municipalities throughout Japan.
The hospital service use rate was approximately 68%. Osteoporotic fractures accounted for 40% of all cases. There were no regional differences in the incidence of metabolic syndrome. On examining the physique, lifestyle, and changes in the latter, the proportion of lean persons increased and that of obese persons decreased in all areas. Based on these results, a nursing model was created, and guidelines for community-based nurses to provide health guidance to prevent fracture/osteoporosis were developed.

Research Products

• [Journal Article] Does Trabecular Bone Score (TBS) Improve the Predictive Ability of FRAX® for Major Osteoporotic Fractures According to the Japanese Population-Based Osteoporosis (JPOS) Cohort Study? (2018)
  • Author(s): J Tamaki, M Iki, Y Sato, R Winzenrieth, E Kajita, S Kagamimori
  • Journal Title: JBMM Volume: - Issue: 1 Pages: 1-10
  • DOI: 10.1007/s00774-018-0910-7
  • Peer Reviewed / Open Access
• [Journal Article] Muscle strength is associated with bone health independently of muscle mass in postmenopausal women: the Japanese Population-based Osteoporosis study (2017)
  • Author(s): T Tachiki, K Kouda, N Dongmei, J Tamaki, M Iki, J Kitagawa, N Takahira, Y Sato, E Kajita, Y Fujita, A Yura, S Kagamimori
  • Journal Title: J. Bone Mineral Metabolism Volume: - Issue: 1 Pages: 1-7
  • DOI: 10.1007/s00774-017-0895-7
  • Peer Reviewed / Open Access
• [Journal Article] Relative Importance of Central and Peripheral Adiposities on Cardiometabolic Variables in Females: A Japanese Population-Based Study (2017)
  • Author(s): K Kouda, N Dongmei, J Tamaki, M Iki, T Tachiki, E Kajita, Y Nakatani, K Uenishi, S Kagamimori, Y Kagawa, H Yoneshima
  • Journal Title: J Clinical Densitometry Volume: 20 Issue: 1 Pages: 58-65
  • DOI: 10.1016/j.jocd.2016.04.004
  • Peer Reviewed / Open Access
• [Journal Article] Total 25-hydroxyvitamin D levels predict fracture risk: Results from the 15-year follow-up of the Japanese Population-based Osteoporosis (JPOS) Cohort Study. (2016)
  • Author(s): Tamaki J, Iki M, Sato Y, Kajita E, Nishino H, Akiba T, Matsumoto T, Kagamimori S
  • Journal Title: Osteoporos Int Volume: E-pub Issue: 6 Pages: 1903-1913
  • DOI: 10.1007/s00198-017-3967-6
  • Peer Reviewed / Open Access
• [Presentation] Bone mineral density predicts arterial stiffness: a 10-year follow-up of the JPOS study (2017)
  • Author(s): M Jaalkhorol, Y Fujita, K Kouda, T Tachiki, J Tamaki, M Komatsu, N Dongmei, E Kajita, A Yura, S Kagamimori, M Iki
  • Organizer: 第28回日本疫学会
• [Presentation] Daily physical activity is associated with smaller decrease in bone mineral density (2017)
  • Author(s): T Tachiki, M Iki, K Kouda, J Tamaki, J Kitagawa, E Kajita, S Kagamimori
  • Organizer: IEA2017
  • Int'l Joint Research
• [Presentation] Relationship between natto intake and the risk of osteoporotic fracture in postmenopausal women: The Japanese Population-based Osteoporosis (JPOS) Cohort study (2017)
  • Author(s): A Kojima, K Kamiya, E Kajita, Y Sato, S Ikehara, K Kouda, J Tamaki, M Iki, S Kagamimori
  • Organizer: IEA2017
  • Int'l Joint Research
• [Presentation] Hand-grip strength as a predictor of site-specific osteoporotic fracture risk in postmenopausal women: The Japanese Population-based Osteoporosis (JPOS) Cohort Study (2017)
  • Author(s): K Kamiya, E Kajita, T Tachiki, K Kouda, Y Sato, S Ikehara, J Tamaki, M Iki, S Kagamimori
  • Organizer: IEA2017
  • Int'l Joint Research
• [Presentation] DXA-image based hip geometry may improve prediction of hip fracture risk based on bone density: The Japanese Population-based Osteoporosis Cohort Study (2017)
  • Author(s): M. Iki, N. DongMei, J. Tamaki, Y. Sato, T. Tachiki, K. Kouda, E. Kajita, S. Kagamimori
  • Organizer: 44th European Calcified Tissue Congress (ECTS2017)
  • Int'l Joint Research
• [Presentation] 低骨密度は上腕ー足首脈波伝播速度を速めるか－JPOSコホート研究による縦断的検討 (2016)
  • Author(s): 玉置淳子、小松美砂、梶田悦子、新井清美、J Myadagmaa、佐藤裕保、甲田勝康、立木隆広、新田明美、池原賢代、臼田寛、伊木雅之、鏡森定信、香川芳子、米島秀夫
  • Organizer: 第８７回日本衛生学会学術総会
• [Presentation] 上腕・足首脈波伝播速度値は脆弱性骨折リスクと関連する－the Japanese Population-based Osteoporosis (JPOS) Cohort Study (2016)
  • Author(s): 玉置淳子、伊木雅之、梶田悦子、小松美砂、立木隆広、新田明美、甲田勝康、臼田寛、由良晶子、佐藤裕保、濱田昌実、池原賢代、鏡森定信、香川芳子、米島秀夫
  • Organizer: 第34回日本骨代謝学会・第３回アジア太平洋骨代謝学会
• [Presentation] 地域在住女性における頸動脈内膜複合体厚肥厚とアルブミン尿は関連する－JPOS Studyの断面解析－ (2016)
  • Author(s): 濱田昌実、梶田悦子、立木隆広、臼田寛、新田明美、新井清美、池原賢代、由良晶子、甲田勝康、玉置淳子、伊木雅之
  • Organizer: 第6回日本腎臓リハビリテーション学会
• [Presentation] 中高年日本女性では腰椎骨密度と筋量は関連する－body mass index別にみた骨密度と脂肪量及び筋量の関連の検討ー (2015)
  • Author(s): 立木隆広、伊木雅之、玉置淳子、梶田悦子、佐藤裕保、鏡森定信、香川芳子、米島秀夫
  • Organizer: 第17回日本骨粗鬆症学会
  • Place of Presentation: 広島
  • Year and Date: 2015-09-17
• [Presentation] 血中25水酸化ビタミン低値は骨折リスクを高める－JPOS Cohort Study－ (2015)
  • Author(s): 玉置淳子、伊木雅之、佐藤裕保、梶田悦子、西野治身、稲葉隆、松本俊夫、鏡森定信、香川芳子、米島秀夫
  • Organizer: 第33回日本骨代謝学会
  • Place of Presentation: 東京
  • Year and Date: 2015-07-23
• [Presentation] 日本人中高年女性において筋力及び平衡機能は日常役割機能に関連する－JPOS Cohort Studyの断面解析－ (2015)
  • Author(s): 立木隆広、伊木雅之、北川淳、高平尚伸、玉置淳子、梶田悦子、鏡森定信、香川芳子、米島秀夫
  • Organizer: 第18回日本運動疫学会
  • Place of Presentation: 名古屋
  • Year and Date: 2015-06-20