Development of the detection method for animal cysticercosis and the investigation of the genetic factors for host specificity
| Project/Area Number |
15H05261
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 海外学術 |
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| Research Field |
Veterinary medical science
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| Research Institution | Yamaguchi University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
迫 康仁 旭川医科大学, 医学部, 教授 (40312459)
伊藤 亮 旭川医科大学, 医学部, 客員教授 (70054020)
岡本 宗裕 京都大学, 霊長類研究所, 教授 (70177096)
佐藤 宏 山口大学, 共同獣医学部, 教授 (90211945)
水上 洋一 山口大学, 大学研究推進機構, 教授 (80274158)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥16,900,000 (Direct Cost: ¥13,000,000、Indirect Cost: ¥3,900,000)
Fiscal Year 2017: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2015: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
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| Keywords | 嚢虫症 / テニア症 / 無鉤条虫 / アジア条虫 / 血清検査 / 宿主特異性 / 人獣共通感染症 / 条虫 / 感染症 / 寄生虫 / 疫学調査 |
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| Outline of Final Research Achievements |
In this study, it was aimed to develop the detection method for cysticercosis, caused by Taenia saginata or Taenia asiatica, in cattle and pigs. Field surveys in the endemic areas were conducted using the developed serology, and it revealed the method can detect T. saginata cysticercosis in cattle. Further extensive surveys are needed to examine the sensitivity and specificity of the method, and whether the method can detect T. asiatica cysticercosis in pig.
It was for the first time directly demonstrated that cattle can be the intermediate host for the hybrid descendant between T. saginata and T. asiatica. This study indicates the possibility that comparative genomics can reveal the genetic factors controlling the host specificity of T. saginata and T. asiatica.
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Report
(4 results)
Research Products
(13 results)
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[Journal Article] Swine cysticercosis in the Karangasem district of Bali, Indonesia: An evaluation of serological screening methods2016
Author(s)
Kadek Swastika, Nyoman Sadra Dharmawan, I. Ketut Suardita, I. Nengah Kepeng, Toni Wandra, 1, Yasuhito Sako, Munehiro Okamoto, Tetsuya Yanagida, Mizuki Sasaki, Patrick Giraudoux, Minoru Nakao, Takahiko Yoshida, Luh Putu Eka Diarthini, I. Made Sudarmaja, Ivan Elisabeth Purba, Christine M. Budke, Akira Ito
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Journal Title
Acta Tropica
Volume: 163
Pages: 46-53
DOI
Related Report
Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
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