MEMS for electron microscopy to study nanobiology and its application to observation of bacterial dynamics
| Project/Area Number |
15H05416
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Nano/Microsystems
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
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| Research Collaborator |
OHNO Teruaki テクネックス工房, 技術者
KAKUSHIMA Kuniyuki 東京工業大学, 工学院, 准教授 (50401568)
OMATA Tatsuo 名古屋大学, 生命農学研究科, 教授 (50175270)
TAKATANI Nobuyuki 名古屋大学, 生命農学研究科, 研究員
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥24,310,000 (Direct Cost: ¥18,700,000、Indirect Cost: ¥5,610,000)
Fiscal Year 2017: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2016: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
Fiscal Year 2015: ¥13,390,000 (Direct Cost: ¥10,300,000、Indirect Cost: ¥3,090,000)
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| Keywords | MEMS / 電子顕微鏡 / 液体セル / 細菌 / 動態観察 / MEMS液体セル / マイクロ・ナノデバイス / ナノバイオ / マイクロ流路 / 培養チャンバ / マイクロナノデバイス |
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| Outline of Final Research Achievements |
Although specimens should normally be placed in vacuum condition for electron microscopes, we developed micro-electro-mechanical systems to visualize in-liquid bacteria. In this project, we developed a specimen holder to control cell cultural conditions, and a microfluidic device with a electron transparent membrane which separate vacuum and liquid. By using them, we visualized the dynamic motions of bubbles in liquid and droplets on the membrane, and observed cyanobacteria under cultural condition for long time.
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Report
(4 results)
Research Products
(5 results)
