Symmetry breaking of sequence information and emergence of genetic information in templated ligation system
| Project/Area Number |
15H05460
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (A)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Mathematical physics/Fundamental condensed matter physics
|
|---|
| Research Institution | Tohoku University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2015-04-01 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
Fiscal Year 2015: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
|
|---|
| Keywords | 生命の起源 / 鋳型ライゲーション / 生物物理 / 統計力学 / DNA / パターン形成 / 非平衡 |
|---|
| Outline of Final Research Achievements |
The emergence of molecular species, which can stably keep and replicate its genetic information, is central to the origin of life. However, the mechanism leading to such emergence remains unknown. Here, on the basis of our previously proposed mechanism for the spontaneous emergence of molecular-species-like structure in templated ligation reaction, we investigated the detailed conditions for this emergence and the interaction between multiple molecular species. In addition, control of information replication error in the templated ligation was achieved.
|
Report
(4 results)
Research Products
(11 results)
