| Budget Amount *help |
¥24,180,000 (Direct Cost: ¥18,600,000、Indirect Cost: ¥5,580,000)
Fiscal Year 2017: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2016: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
Fiscal Year 2015: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
|
|---|
| Outline of Final Research Achievements |
Non-equilibrium phenomena such as abnormal diffusion have been reported in living cells and cell membrane models. As a factor of the non-equilibrium phenomenon, we assumed that the dense polymer becomes viscoelastic and behaves differently from bulk when confining high concentration polymer solution in the microspace. In this study, we aimed to elucidate the non-equilibrium phenomenon due to the interaction between membrane and polymer by analyzing molecular diffusion and membrane fluctuation using a cell model confining a polymer solution. As a result, a non-equilibrium phenomenon such as (i) abnormal molecule diffusion, (ii) membrane deformation of the cell membrane model due to internal viscosity, for example, was observed when a highly crowded polymer was confined in the microspace.
|
