Studies on Metastasis of Colon Cancer Using Mouse Models
| Project/Area Number |
15H05574
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Tumor biology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Research Collaborator |
Yamanashi Yuji 東京大学, 医科学研究所, 教授 (40202387)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥23,530,000 (Direct Cost: ¥18,100,000、Indirect Cost: ¥5,430,000)
Fiscal Year 2016: ¥11,700,000 (Direct Cost: ¥9,000,000、Indirect Cost: ¥2,700,000)
Fiscal Year 2015: ¥11,830,000 (Direct Cost: ¥9,100,000、Indirect Cost: ¥2,730,000)
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| Keywords | 腸管腫瘍 / 悪性化 / モデルマウス / 癌 / 浸潤・転移 / 大腸癌 |
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| Outline of Final Research Achievements |
Most malignant tumor deaths are caused by metastasis with tissue invasion capacity of tumor cells. We previously developed a new mouse model for intestinal malignant tumors. In this study, we demonstrate that tumor progression in these model mice is regulated by tumor microenvironment. Our finding may open new horizons in research of tumor progression and treatment of malignant tumors.
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Report
(3 results)
Research Products
(6 results)
