Post-translational regulation of auxin biosynthesis in Arabidopsis
| Project/Area Number |
15H05623
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Bioorganic chemistry
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Research Collaborator |
KASAHARA hiroyuki 東京農工大学, 教授
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| Project Period (FY) |
2015-04-01 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥24,050,000 (Direct Cost: ¥18,500,000、Indirect Cost: ¥5,550,000)
Fiscal Year 2018: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2017: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
Fiscal Year 2016: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
Fiscal Year 2015: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
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| Keywords | 植物ホルモン / オーキシン / フラビン含有モノオキシゲナーゼ / 生合成 |
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| Outline of Final Research Achievements |
Auxins, a class of plant hormones, are essential for plant growth and development. The natural auxin indole-3-acetic acid (IAA) is biosynthesized from tryptophan via indole-3-pyruvic acid by TAA aminotransferase and YUCCA flavin-containing monooxygenase families. Although much progresses in the transcriptional regulation of IAA biosynthetic genes has been made in recent years, its post-translational regulation has remained unclear. In this study, we identified and analyzed a YUCCA-interacting protein to elucidate the regulation mechanism of IAA biosynthesis in Arabidopsis. Our results suggest that the regulation of YUCCAs at the level of protein has a role in the homeostatic regulation of IAA.
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| Academic Significance and Societal Importance of the Research Achievements |
植物ホルモンとして働くオーキシンの生合成における鍵酵素タンパク質であるYUCCA（ユッカ）ファミリーが、遺伝子レベルだけではなく、タンパク質レベルの調節によっても制御されている可能性が示されました。今回モデル植物のシロイヌナズナから見出したYUCCAの調節タンパク質のホモログ（よく似たタンパク質）は他の双子葉植物にも存在するので、本メカニズムは様々な植物において共通したものかもしれません。
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Report
(5 results)
Research Products
(20 results)
