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Elucidation of effects of deformation behavior of red blood cell membranes in unsteady motion on the mass transfer

Research Project

Project/Area Number 15H06026
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Fluid engineering
Research InstitutionTohoku University

Principal Investigator

Miyauchi Suguru  東北大学, 流体科学研究所, 助教 (00758691)

Project Period (FY) 2015-08-28 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords数値流体力学 / 赤血球 / 流体構造連成 / 物質輸送 / 数値シミュレーション / 数値積分 / 循環器・高血圧 / 計算物理 / 流体
Outline of Final Research Achievements

For elucidation of effects of the deformation of the red blood cell membranes in unsteady motion on the mass transfer in a capillary with complex geometry, the analysis codes of the fluid-membrane coupling and the mass transfer across the membrane have been developed. The level set method is introduced for the extension to three-dimensional analyses, and the computational algorism for high volume conservation of the fluid inside the red blood cell is implemented. The elucidation of the effects of the deformation of the red blood cell membrane on the capacity of mass diffusion remains as the future work.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • Research Products

    (7 results)

All 2017 2016 2015 Other

All Int'l Joint Research (1 results) Presentation (6 results) (of which Int'l Joint Research: 3 results,  Invited: 1 results)

  • [Int'l Joint Research] Royal Institute of Technology(スウェーデン)

    • Related Report
      2015 Annual Research Report
  • [Presentation] Development of Numerical Method for Mass Transfer across the Moving Membrane with Selective Permeability: Approximation of the Membrane Shape by Level Set Method for Numerical Integral2017

    • Author(s)
      Suguru Miyauchi, Toshiyuki Hayase
    • Organizer
      19th International Conference on Computational Fluid Dynamics
    • Place of Presentation
      バルセロナ(スペイン)
    • Year and Date
      2017-02-26
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 傾斜遠心力場における円形カプセル挙動の2 次元数値解析(膜の弾性の影響)2017

    • Author(s)
      宮内優, 早瀬敏幸, Luca Brandt, Fredrik Lundell, Shervin Bagheri
    • Organizer
      日本機械学会 第29回バイオエンジニアリング講演会
    • Place of Presentation
      ウインクあいち(愛知県名古屋市)
    • Year and Date
      2017-01-19
    • Related Report
      2016 Annual Research Report
  • [Presentation] Two-Dimensional Numerical Simulation for the Effect of Capsule Elasticity on its Behavior near a Plate in a Fluid under an Inclined Centrifugal Force Field2016

    • Author(s)
      Suguru Miyauchi, Toshiyuki Hayase, Luca Brandt, Fredrik Lundell, Shervin Bagheri
    • Organizer
      The 16th International Conference on Biomedical Engineering
    • Place of Presentation
      シンガポール(シンガポール)
    • Year and Date
      2016-12-07
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Three-Dimensional Numerical Analysis for an Erythrocyte Behavior near a wall in a fluid under an inclined centrifugal force2016

    • Author(s)
      Suguru Miyauchi, Toshiyuki Hayase, Arash Alizad Banaei, Jean-Christophe Loiseau, Luca Brandt
    • Organizer
      The 16th International Symposium on Advanced Fluid Information
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-10-10
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 傾斜遠心力場におけるカプセル挙動の2次元数値解析(傾斜遠心力の角度がカプセル挙動に与える影響)2016

    • Author(s)
      宮内優, 早瀬敏幸,Luca Brandt, Fredrik Lundell, Shervin Bagheri
    • Organizer
      日本流体力学会年会2016
    • Place of Presentation
      名古屋工業大学(愛知県名古屋市)
    • Year and Date
      2016-09-26
    • Related Report
      2016 Annual Research Report
  • [Presentation] Two-dimensional simulation of interaction between solid wall and capsule in fluid under centrifugal force field2015

    • Author(s)
      宮内優
    • Organizer
      International Workshop on Flow Dynamics and Spintronics
    • Place of Presentation
      ストックホルム(スウェーデン)
    • Year and Date
      2015-11-12
    • Related Report
      2015 Annual Research Report
    • Invited

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Published: 2015-08-26   Modified: 2018-03-22  

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