Development of anti-Markovnikov addition reaction catalyzed by pincer-type Fischer carbene complex

• Project/Area Number: 15H06202
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Organic chemistry
• Research Institution: Tokyo Institute of Technology
• Principal Investigator: Takahashi Kohei 東京工業大学, 理学院, 助教 (00756108)
• Project Period (FY): 2015-08-28 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000); Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: イリジウム / カルベン錯体 / Fischer型カルベン / アルケン / アルキン / 有機金属 / 触媒反応 / カルベン配位子 / アンチマルコフニコフ / 有機金属錯体

Outline of Final Research Achievements

Synthesis of iridium complexes bearing pincer-type Fischer carbene ligand was accomplished. The reactivity of the complexes were investigated to find novel reactivity with alkenes and alkynes. When picanole borane and aliphatic ethers were treated in the presence of catalytic amount of the iridium complex, retro-hydroalkoxylation was proceeded to give alkene, whereas such product were not obtained with other iridium complexes. Such distinctive reactivity is supposed to be derived from the supported Fischer carbene structure.