Hydrodynamic study on propulsive mechanisms of undulatory swimming

• Project/Area Number: 15H06314
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Mathematical physics/Fundamental condensed matter physics
• Research Institution: Kyoto University
• Principal Investigator: Ishimoto Kenta 京都大学, 白眉センター, 特定助教 (00741141)
• Research Collaborator: GAFFNEY Eamonn University of Oxford, Wolfson Centre for Mathematical Biology, Mathematical Institute, Associate Professor ; TAKEHIRO Shin-Ichi 京都大学, 数理解析研究所, 准教授 (30274426)
• Project Period (FY): 2015-08-28 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000); Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: 生物流体力学 / 低レイノルズ数流れ / 最適化 / 流体力学 / 鞭毛 / 遊泳 / 推進力 / 数値計算

Outline of Final Research Achievements

Undulatory swimming at low Reynolds number has been investigated. By using a genetic algorithm, optimal swimming on the swimming efficiency is computed, and it is found that he results are compatible with real biological swimmers. Further studies on hyperactivation of mammalian spermatozoa has demonstrated multiple mechanical functions in fertilization processes by our fluid dynamic numerical computation.

Research Products

• [Int'l Joint Research] オックスフォード大学(英国)
• [Int'l Joint Research] University of Oxford(英国)
• [Journal Article] Mechanical tuning of mammalian sperm behaviour by hyperactivation, rheology and substrate adhesion: a numerical exploration (2016)
  • Author(s): Kenta Ishimoto and Eamonn A. Gaffney
  • Journal Title: Journal of the Royal Society Interface Volume: 13 Issue: 124 Pages: 20160633-20160633
  • DOI: 10.1098/rsif.2016.0633
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Hydrodynamic evolution of sperm swimming: Optimal flagella by a genetic algorithm (2016)
  • Author(s): Kenta Ishimoto
  • Journal Title: Journal of Theoretical Biology Volume: 399 Pages: 166-174
  • DOI: 10.1016/j.jtbi.2016.03.041
  • Peer Reviewed / Acknowledgement Compliant
• [Presentation] 流体力学的に最適な鞭毛遊泳について (2017)
  • Author(s): 石本健太
  • Organizer: 日本物理学会第72回年次大会
  • Place of Presentation: 大阪大学（大阪府豊中市）
  • Year and Date: 2017-03-19
• [Presentation] Sperm dynamics near adhesive boundaries (2016)
  • Author(s): Kenta Ishimoto and Eamonn A. Gaffney
  • Organizer: Interdisciplinary Applications of Nonlinear Science
  • Place of Presentation: 鹿児島大学（鹿児島市）
  • Year and Date: 2016-11-05
• [Presentation] A study on optimal flagellar swimming (2016)
  • Author(s): 石本健太
  • Organizer: 生物流体現象におけるミクロ運動とマクロ運動
  • Place of Presentation: 京都大学（京都府京都市）
  • Year and Date: 2016-10-25
• [Presentation] Multiple mechanical functions of sperm hyperactivation (2016)
  • Author(s): Kenta Ishimoto and Eamonn A. Gaffney
  • Organizer: International Conference: Microswimmers 2016
  • Place of Presentation: Bonn (Germany)
  • Year and Date: 2016-10-05
• [Presentation] Hydrodynamic evolution of sperm swimming (2016)
  • Author(s): Kenta Ishimoto
  • Organizer: 2016 Annual Meeting of the Society for Mathematical Biology and European Conference for Mathematical and Theoretical Biology
  • Place of Presentation: University of Nottingham (Nottingham, UK)
  • Year and Date: 2016-07-14
• [Remarks]
  • URL: http://www.kurims.kyoto-u.ac.jp/~ishimoto/jp/
• [Remarks]
  • URL: http://www.kurims.kyoto-u.ac.jp/~ishimoto/jp/