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resting state brain functional connectivity in gambling disorder

Research Project

Project/Area Number 15H06336
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Psychiatric science
Research InstitutionKyoto University

Principal Investigator

Tsurumi Kosuke  京都大学, 医学研究科, 助教 (20760854)

Research Collaborator KAWADA Ryosaku  
TAKEUCHI Hideaki  
MURAO Takuro  
TAKEMURA Ariyoshi  
FUJIMOTO Atsushi  
Project Period (FY) 2015-08-28 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords神経科学 / ギャンブル障害 / 依存症 / MRI / ゲノム
Outline of Final Research Achievements

In this project, we investigated the association between functional and structural brain alteration, especially resting state functional alteration, of gambling disorder (GD) patients and clinical characteristics or gene variant to elucidate pathophysiology of GD. We found a need to classify GD into two subtypes, and revealed a part of brain network dysfunction in GD. Our findings would contribute to elucidate pathophysiology of GD.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • Research Products

    (18 results)

All 2017 2016 2015

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Open Access: 3 results) Presentation (15 results) (of which Int'l Joint Research: 4 results,  Invited: 1 results)

  • [Journal Article] Common and differential brain abnormalities in gambling disorder subtypes based on risk attitude.2017

    • Author(s)
      Takeuchi H, Tsurumi K, Murao T, Takemura A, Kawada R, Urayama SI, Aso T,Sugihara GI, Miyata J, Murai T, Takahashi H.
    • Journal Title

      Addictive Behaviors

      Volume: 69 Pages: 48-54

    • DOI

      10.1016/j.addbeh.2017.01.025

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Deficit of State-Dependent Risk-Attitude Modulation in Gambling Disorder.2017

    • Author(s)
      Atsushi Fujimoto, Kosuke Tsurumi, Ryosaku Kawada, Takuro Murao, Hideaki Takeuchi, Toshiya Murai, Hidehiko Takahashi
    • Journal Title

      Translational Psychiatry

      Volume: 7

    • NAID

      120006027095

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Heterogeneity of Loss Aversion in Pathological Gambling.2015

    • Author(s)
      Takeuchi,H., Kawada, R., Tsurumi, K., Yokoyama, N., Takemura, A., Murao, T., Murai, T. & Takahashi, H.
    • Journal Title

      Journal of Gambling Study

      Volume: Epub ahead of print Issue: 4 Pages: 1143-1154

    • DOI

      10.1007/s10899-015-9587-1

    • NAID

      120005997647

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] ギャンブル障害の研究と臨床2017

    • Author(s)
      鶴身孝介
    • Organizer
      第18回サイコセラピー学会
    • Place of Presentation
      兵庫医科大学(兵庫県西宮市)
    • Year and Date
      2017-03-25
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] ギャンブル障害の損失回避性に基づいたサブタイプにおける脳構造の違いについて2017

    • Author(s)
      竹内秀暁、鶴身孝介、村尾託朗、竹村有由、川田良作、浦山慎一、麻生俊彦、杉原玄一、宮田淳、村井俊哉、高橋英彦
    • Organizer
      平成29年度日本ヒト脳機能マッピング学会
    • Place of Presentation
      京都大学100周年時計台記念館(京都市左京区)
    • Year and Date
      2017-03-09
    • Related Report
      2016 Annual Research Report
  • [Presentation] 病的賭博における強化学習の神経基盤2016

    • Author(s)
      村尾託朗 鶴身孝介 竹内秀暁 川田良作 水田弘人 佐々木仁 村井俊哉 高橋英彦
    • Organizer
      平成28年度宮古島神経科学カンファレンス
    • Place of Presentation
      ホテルブリーズベイマリーナ(沖縄県宮古島市)
    • Year and Date
      2016-11-11
    • Related Report
      2016 Annual Research Report
  • [Presentation] 嗜癖物質への早期暴露や摂取量、嗜癖罹病期間による脳の影響2016

    • Author(s)
      鶴身孝介
    • Organizer
      第51回日本アルコール・アディクション医学会学術総会
    • Place of Presentation
      タワーホール船堀 (東京都江戸川区)
    • Year and Date
      2016-10-07
    • Related Report
      2016 Annual Research Report
  • [Presentation] 病的賭博における強化学習の神経基盤2016

    • Author(s)
      村尾託朗 鶴身孝介 竹内秀暁 川田良作 竹村有由 村井俊哉 高橋英彦
    • Organizer
      平成28年度日本生物学的精神医学会
    • Place of Presentation
      福岡国際会議場(福岡市博多区)
    • Year and Date
      2016-09-08
    • Related Report
      2016 Annual Research Report
  • [Presentation] ltered resting state functional connectivity between the insula and DMN region reflects duration of illness in gambling disorder patients.2016

    • Author(s)
      Tsurumi K, Aso T, Kawada R, Hazama M, Miyata J, Fukuyama H, Murai T, Takahashi H
    • Organizer
      The International Society for Biomedical Research on Alcoholism (ISBRA) and the European Society for Biomedical Research on Alcoholism (ESBRA) Berlin 2016 World Congress on Alcohol and Alcoholism
    • Place of Presentation
      Technische Universitat Berlin, Berlin, Germany
    • Year and Date
      2016-09-02
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Flexible Modulation of Risk Attitude during Decision-Making under Quota and Its Impairments in Gambling Disorders2016

    • Author(s)
      Atsushi Fujimoto, Kosuke Tsurumi, Ryosaku Kawada, Takuro Murao, Hideaki Takeuchi, Toshiya Murai, Hidehiko Takahashi
    • Organizer
      6th Motivation and Cognitive Control (MCC) Symposium
    • Place of Presentation
      St.Andrews University (Scotland)
    • Year and Date
      2016-08-24
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Resting state functional connectivity between insula and large-scale brain networks in gambling disorder patients.2016

    • Author(s)
      Kosuke Tsurumi, Toshihiko Aso, Ryosaku Kawada, Masaaki Hazama, Genichi Sugihara, Jun Miyata, Hidenao Fukuyama, Toshiya Murai, Hidehiko Takahashi
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2016-07-20
    • Related Report
      2016 Annual Research Report
  • [Presentation] Resting state functional connectivity between insula and DMN region in gambling disorder patients2016

    • Author(s)
      Kosuke Tsurumi, Toshihiko Aso, Ryosaku Kawada, Masaaki Hazama, Jun Miyata, Hidenao Fukuyama, Toshiya Murai, Hidehiko Takahashi
    • Organizer
      22th annual Meeting of theOrganization for Human Brain Mapping
    • Place of Presentation
      Palexbo Exhibition and Congress Center Geneva, Switzerland
    • Year and Date
      2016-06-26
    • Related Report
      2016 Annual Research Report 2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ギャンブル障害の脳画像研究2016

    • Author(s)
      鶴身孝介
    • Organizer
      第112回日本精神神経学会学術総会
    • Place of Presentation
      幕張メッセ(千葉市)
    • Year and Date
      2016-06-02
    • Related Report
      2016 Annual Research Report
  • [Presentation] ギャンブル障害の脳画像研究2016

    • Author(s)
      鶴身孝介
    • Organizer
      第3回日本依存症医療研究会
    • Place of Presentation
      兵庫県立光風病院 (神戸市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] ギャンブル障害患者の島皮質をseedとした安静時脳機能結合について2015

    • Author(s)
      鶴身孝介, 川田良作, 村尾託朗, 竹内秀暁, 竹村有由, 挾間雅章, 村井俊哉, 高橋英彦
    • Organizer
      平成27年度アルコール・薬物依存関連学会合同学術総会
    • Place of Presentation
      神戸国際会議場(神戸市中央区)
    • Year and Date
      2015-10-11
    • Related Report
      2015 Annual Research Report
  • [Presentation] 病的賭博における強化学習の神経基盤2015

    • Author(s)
      村尾託朗 鶴身孝介 竹内秀暁 川田良作 竹村有由 村井俊哉 高橋英彦
    • Organizer
      平成27年度アルコール・薬物依存関連学会合同学術総会
    • Place of Presentation
      神戸国際会議場(神戸市中央区)
    • Year and Date
      2015-10-11
    • Related Report
      2015 Annual Research Report
  • [Presentation] The effect of Taq1A polymorphism on the white matter integrity in gambling disorder.2015

    • Author(s)
      Ariyoshi Takemura, Masanori Isobe, Jun Miyata, Kosuke Tsurumi, Ryosaku Kawada, Naoto Yokoyama, Masaaki Hazama, Toshiya Murai, Hidehiko Takahashi
    • Organizer
      International Society of Addiction Medicine(ISAM) 2015
    • Place of Presentation
      Caird Hall, Dundee Scotland
    • Year and Date
      2015-10-05
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ギャンブル障害患者の安静時脳機能結合について2015

    • Author(s)
      鶴身孝介, 川田良作, 狭間雅章, 村尾託朗, 竹内秀暁, 竹村有由, 杉原玄一, 宮田淳, 村井俊哉, 高橋英彦
    • Organizer
      第37回 日本生物学的精神医学会
    • Place of Presentation
      タワーホール船堀(東京都江戸川区)
    • Year and Date
      2015-09-24
    • Related Report
      2015 Annual Research Report

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Published: 2015-08-26   Modified: 2018-03-22  

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