| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
Escherichia coli acquired a radioresistant phenotype by adaptive evolution, wherein gamma-rays constituted the selection pressure. Furthermore, a gradual increase in the radioresistance was noted during the evolution process, and the expression levels of many genes of the evolved radioresistant E. coli differed from those of the wild type E. coli. These results suggest that changes in the expression levels of many genes are involved in evolution of the biological defense mechanism in organisms such as bacteria with high radioresistance.
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