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Analysis of hypertension related gene polymorphisms related to health maintenance of elderly people

Research Project

Project/Area Number 15K01699
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Applied health science
Research InstitutionMukogawa Women's University (2017-2018)
Mukogawa Women's University Junior College Division (2015-2016)

Principal Investigator

BANNO Mariko  武庫川女子大学, 生活環境学部, 准教授 (90400530)

Co-Investigator(Kenkyū-buntansha) 坂野 史明  日本女子大学, 家政学部, 講師 (00373514)
Research Collaborator MIYATA toshiyuki  
Project Period (FY) 2015-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords健康長寿 / 高齢者 / 高血圧 / 遺伝子多型 / 食生活 / 健康 / 長寿
Outline of Final Research Achievements

In this study, we investigated the eating habits of the elderly people, focusing on centenarians, to clarify the common factors of health longevity. We also examined the relationship between the hypertension related genes and the health maintenance of the elderly people. Our results showed that regardless of regional and age differences, common eating habits (intake status of meat, fish, vegetables, dairy products) and daily life (exercising, having hobbies) are important to healthy longevity. Since the dietary life until adulthood is strongly associated with healthy longevity, it is better to provide dietary education for prevention of lifestyle-related diseases from early childhood on the basis of genotype information of hypertension and arteriosclerosis related gene polymorphism.

Academic Significance and Societal Importance of the Research Achievements

百寿者を中心に高齢者の食生活と遺伝子多型の特徴に関する情報を並行して収集、解析した結果、健康長寿を迎えるために必要な栄養教育やヘルスプロモーションの改善につながる成果が得られた。

Report

(5 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (7 results)

All 2019 2017 2016

All Journal Article (4 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 4 results,  Open Access: 2 results) Presentation (2 results) (of which Invited: 1 results) Book (1 results)

  • [Journal Article] フライ油の劣化過程における遊離脂肪酸生成機構2019

    • Author(s)
      坂野麻里子、坂野史明
    • Journal Title

      オレオサイエンス

      Volume: 19 Pages: 89-92

    • NAID

      130007711484

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Retardation of Free Fatty Acid Formation in Frying Oil by Heating along with Water Spray under Low Oxygen Atmosphere2017

    • Author(s)
      坂野 麻里子, 坂野 史明, 遠藤 泰志, 藤本 健四郎
    • Journal Title

      Journal of Cookery Science of Japan

      Volume: 50 Issue: 6 Pages: 239-244

    • DOI

      10.11402/cookeryscience.50.239

    • NAID

      130006262698

    • ISSN
      1341-1535, 2186-5787
    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Differences in the association between high blood pressure and cognitive functioning among the general Japanese population aged 70 and 80 years: The SONIC study.2016

    • Author(s)
      Ryuno H, Kamide K, Gondo Y, Nakama C, Oguro R, Kabayama M, Kawai T, Kusunoki H, Yokoyama S, Imaizumi Y, Takeya M, Yamamoto H, Takeda M, Takami Y, Itoh N, Yamamoto K, Takeya Y, Sugimoto K, Nakagawa T, Ikebe K, Inagaki H, Masui Y, Ishizaki T, Takayama M, Arai Y, Takahashi R, Rakugi H.
    • Journal Title

      Hypertens Res

      Volume: in press Issue: 7 Pages: 557-63

    • DOI

      10.1038/hr.2016.25

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association Analysis of FOXO3 Longevity Variants With Blood Pressure and Essential Hypertension.2016

    • Author(s)
      Morris BJ1, Chen R2, Donlon TA2, Evans DS3, Tranah GJ3, Parimi N3, Ehret GB4, Newton-Cheh C5, Seto T6, Willcox DC7, Masaki KH8, Kamide K9, Ryuno H10, Oguro R11, Nakama C11, Kabayama M10, Yamamoto K11, Sugimoto K11, Ikebe K12, Masui Y13, Arai Y14, Ishizaki T13, Gondo Y15, Rakugi H11, Willcox BJ8.
    • Journal Title

      Am J Hypertens.

      Volume: in press Issue: 11 Pages: 1292-1300

    • DOI

      10.1093/ajh/hpv171

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] 百寿者の食事2016

    • Author(s)
      坂野麻里子
    • Organizer
      日本臨床栄養学会総会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2016-10-07
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] 低酸素雰囲気はフライ油中の遊離脂肪酸生成を抑制する2016

    • Author(s)
      坂野麻里子、遠藤泰志、藤本健四郎
    • Organizer
      日本臨床栄養学会総会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2016-10-07
    • Related Report
      2016 Research-status Report
  • [Book] 栄養教育論2017

    • Author(s)
      田中敬子、前田佳予子、赤松利恵、北村真理、小林知未、高橋志乃、橘ゆかり、坂野麻里子、本多美預子、餅美知子、矢埜みどり
    • Total Pages
      173
    • Publisher
      朝倉書店
    • Related Report
      2016 Research-status Report

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Published: 2015-04-16   Modified: 2020-03-30  

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