| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
We performed the studies on retinal circuit mediating circadian photoentrainment in human and mouse. In a series of our study in mouse retina, we could find a novel retinogram response possibly demonstrating photorensposens of intrinsically photosensitive retinal ganglion cells (ipRGC). The behavior of this response was almost same as that of ipRGC. Neurons in suprachiasmatic nucleus responded to polychromatic light more than monochromatic light. However, it was reported that monochromatic light was more effective for puppilarry light reflex than polychromatic light in human. These facts indicate that we are required to start a detailed comparative study on retinal circuits mediating circadian photoentrainment.
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