| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
To reveal the plant immune components, we have performed phosphoproteomics approach, and identified PSIG1 that functions as a negative regulator of cell death during pathogen infection. For exploring of the molecular function of PSIG1, we assessed the subcellular localization of PSIG1, and identified PSIG1 interacting protein. One of the interactors of SMG7 which functions as a regulator of mRNA decay in Arabidopsis thaliana. PSIG1 physically binds to SMG7, and PSIG1 and SMG7 were co-localized around P-bodies using Agroinfiltration method in Nicotiana benthamiana. These results suggest that PSIG1 might regulate mRNA metabolism for controlling cell death during pathogen infection.
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