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Establishment of new reproductive examination thoughout pregnancy in one of biggest horse, Japanese heavy draft horses

Research Project

Project/Area Number 15K07735
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Veterinary medical science
Research InstitutionObihiro University of Agriculture and Veterinary Medicine

Principal Investigator

Nambo Yasuo  帯広畜産大学, 畜産学部, 教授 (20731623)

Co-Investigator(Kenkyū-buntansha) 羽田 真悟  帯広畜産大学, 畜産学部, 助教 (40553441)
滄木 孝弘  帯広畜産大学, 畜産学部, 助教 (40624721)
Research Collaborator SATO Fumio  
MURASE Harutaka  
KIMURA Yuki  
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords子宮胎盤厚 / プロジェステロン / エストラジオール / 超音波画像診断装置 / 重輓馬 / 繁殖 / 妊娠 / 流産 / 超音波画像件検査 / 馬 / 超音波画像検査 / 胎盤 / 子宮 / 胎盤炎 / 超音波 / 3D / 分娩
Outline of Final Research Achievements

Japanese heavy draft horses are heaviest and their body weight can be over 1,000 kg. therefore it is difficult to examine reproductive situation during pregnancy. In the present study, the combined thickness of the uterus and placenta (CTUP) and ultrasonographic images of uteroplacental tissues were investigated in pregnant heavy draft horses during mid-to late pregnancy.
As a result, CTUP increased as pregnancy progress to 12 months. Survive fetal and foal rate before or at parturition is lower in the abnormal group than in the control group. These findings suggest that increased CTUP and placental separation would reflect placentitis and abnormal pregnancies and may help to detect them in heavy draft horses. The present result might be useful to reduce pregnancy failure in large animals as well as in Japanese heavy draft horses.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (47 results)

All 2018 2017 2016 2015 Other

All Journal Article (21 results) (of which Int'l Joint Research: 5 results,  Peer Reviewed: 19 results,  Open Access: 11 results) Presentation (20 results) (of which Int'l Joint Research: 3 results,  Invited: 4 results) Book (3 results) Remarks (3 results)

  • [Journal Article] Combined thickness of the uterus and placenta and ultrasonographic examinations of uteroplacental tissues in normal pregnancy, placentitis, and abnormal parturitions in heavy draft2018

    • Author(s)
      Kimura Y, Haneda S, Aoki T, Furuoka H, Miki W, Fukumoto N, Matsui M, Nambo Y
    • Journal Title

      J Equine Sci.

      Volume: 29 Pages: 1-8

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Serum Anti-M?llerian Hormone Concentrations in Mares With Granulosa Cell Tumors Versus Other Ovarian Abnormalities2018

    • Author(s)
      Murase Harutaka、Ball Barry A.、Tangyuenyong Siriwan、Watanabe Gen、Sato Fumio、Hada Tetsuro、Nambo Yasuo
    • Journal Title

      Journal of Equine Veterinary Science

      Volume: 60 Pages: 6-10

    • DOI

      10.1016/j.jevs.2017.10.012

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Identification and expression analysis of cDNA encoding insulin-like growth factor 2 in horses2018

    • Author(s)
      Kohta KIKUCHI, Keisuke SASAKI, Hiroki AKIZAWA, Hayato TSUKAHARA, Hanako BAI, Masashi TAKAHASHI, Yasuo NAMBO, Hiroshi HATA, Manabu KAWAHARA
    • Journal Title

      J Reprod Dev.

      Volume: 64 Pages: 57-64

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Abnormal pregnancies associated with deviation in progestin and estrogen profiles in late pregnant mares: A diagnostic aid2017

    • Author(s)
      Shikichi Mitsumori、Iwata Katsuroku、Ito Katsumi、Miyakoshi Daisuke、Murase Harutaka、Sato Fumio、Korosue Kenji、Nagata Shunichi、Nambo Yasuo
    • Journal Title

      Theriogenology

      Volume: 98 Pages: 75-81

    • DOI

      10.1016/j.theriogenology.2017.04.024

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Signal changes in standing magnetic resonance imaging of osseous injury at the origin of the suspensory ligament in four Thoroughbred racehorses under tiludronic acid treatment2017

    • Author(s)
      Mizobe F, Nomura M, Kato T, Nambo Y, Yamada K.
    • Journal Title

      J Equine Sci.

      Volume: 28 Pages: 87-97

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Foaling rate of mares that were rebred after pregnancy loss in Hidaka, Japan2017

    • Author(s)
      Miyakoshi D, Sato F, Murase H, Inoue Y, Shikichi M, Iwata K, Okai K, Ito K , Nambo Y .
    • Journal Title

      J Equine Sci.

      Volume: 28 Pages: 159-161

    • NAID

      130006251681

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparison of physical body growth and metabolic and reproductive endocrine functions between north and south climates of Japan in trained Thoroughbred yearling horses2017

    • Author(s)
      Tangyuenyong S, Sato F, Nambo Y, Murase H, Endo Y, Tanaka T, Nagaoka K, Watanabe G
    • Journal Title

      J Equine Sci.

      Volume: 28 Pages: 77-86

    • NAID

      130006083339

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Sensitive radioimmunoassay of total thyroxine (T4) in horses using a simple extraction method2017

    • Author(s)
      Tangyuenyong S, Nambo Y, Nagaoka K, Tanaka T, Watanabe G
    • Journal Title

      J. Vet. Med. Sci.

      Volume: 78 Pages: 1294-1300

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 妊娠後期に腸管手術を実施したサラブレッドの血中プロジェステロ2017

    • Author(s)
      佐藤正人、樋口徹、井上哲、後藤忠広、村瀬晴崇、南保泰雄
    • Journal Title

      日獣会誌

      Volume: 70 Pages: 37-43

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effects of dystocia on blood gas parameters, acid-base balance and serum lactate concentration in heavy draft newborn foals2017

    • Author(s)
      Kimura Y, Aoki T, Chiba A, Nambo Y
    • Journal Title

      Journal of Equine Science

      Volume: 28 Issue: 1 Pages: 27-30

    • DOI

      10.1294/jes.28.27

    • NAID

      130005492566

    • ISSN
      1340-3516, 1347-7501
    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Expression of uterine lipocalin 2 and its receptor during early- to mid-pregnancy period in mares2017

    • Author(s)
      Haneda S, Nagaoka K, Nambo Y, Kikuchi M, Nakano Y, Li J, Matsui M, Miyake YI, Imakawa K.
    • Journal Title

      Journal of Reproduction and Development

      Volume: 63 Issue: 2 Pages: 127-133

    • DOI

      10.1262/jrd.2016-096

    • NAID

      130007314637

    • ISSN
      0916-8818, 1348-4400
    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Evidence for a PGF2α auto-amplification system in the endometrium in mares2016

    • Author(s)
      Keisuke Kozai, Shota Tokuyama, Anna Z Szostek, Yuko Toishi, Nobuo Tsunoda, Kazuyoshi Taya, Miki Sakatani, Masashi Takahashi, Yasuo Nambo, Dariusz J Skarzynski, Yuki Yamamoto, Koji Kimura, Kiyoshi Okuda
    • Journal Title

      Reproduction

      Volume: 151 Issue: 5 Pages: 517-526

    • DOI

      10.1530/rep-15-0617

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Autopsy imaging for cardiac tamponade in a Thoroughbred foal2016

    • Author(s)
      Yamada K, Sato F, Horiuchi N, Higuchi T, Kobayashi Y, Sasaki N, Nambo Y
    • Journal Title

      Journal of Equine Science

      Volume: 27 Issue: 3 Pages: 115-118

    • DOI

      10.1294/jes.27.115

    • NAID

      130005265072

    • ISSN
      1340-3516, 1347-7501
    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Quantitative evaluation of cervical cord compression by computed tomographic myelography in Thoroughbred foals2016

    • Author(s)
      Yamada K, Sato F, Hada T, Horiuchi N, Ikeda H, Nishihara K, Sasaki N, Kobayashi Y, Nambo Y
    • Journal Title

      J. Equine Sci.

      Volume: 27 Issue: 4 Pages: 143-148

    • DOI

      10.1294/jes.27.143

    • NAID

      130005250271

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effects of a single use of the GnRH analog buserelin on the induction of ovulation and endocrine profiles in heavy draft mares2016

    • Author(s)
      Miki W, Oniyama H, Takeda N, Kimura Y, Haneda S, Matsui M, Taya K, Nambo Y
    • Journal Title

      J. Equine Sci.

      Volume: 27 Issue: 4 Pages: 149-156

    • DOI

      10.1294/jes.27.149

    • NAID

      130005250231

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] 繁殖雌馬の卵巣機能調節と制御2016

    • Author(s)
      南保泰雄
    • Journal Title

      日獣会誌

      Volume: 69 Pages: 589-596

    • NAID

      130005284868

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Hematological and biochemical features of postpartum fever in the heavy draft mare2016

    • Author(s)
      Aoki T, Kimura Y, Oya A, Chiba A, Ishii M, Nambo Y
    • Journal Title

      Journal of Equine Science

      Volume: 27 Issue: 1 Pages: 13-16

    • DOI

      10.1294/jes.27.13

    • NAID

      130005145045

    • ISSN
      1340-3516, 1347-7501
    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 馬を専門としない獣医師のための馬繁殖検査2016

    • Author(s)
      南保泰雄
    • Journal Title

      臨床獣医

      Volume: 34 Pages: 3-7

    • Related Report
      2015 Research-status Report
  • [Journal Article] A clinical case of equine fungal placentitis with reference to hormone profiles and ultrasonography2015

    • Author(s)
      Murase H, Niwa H, Katayama Y, Sato F, Hada T, Nambo Y
    • Journal Title

      Journal of Equine Science

      Volume: 26 Issue: 4 Pages: 129-133

    • DOI

      10.1294/jes.26.129

    • NAID

      130005124613

    • ISSN
      1340-3516, 1347-7501
    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 馬の産後疾患に対する治療法-胎盤停滞と続発疾患-2015

    • Author(s)
      南保泰雄
    • Journal Title

      家畜診療

      Volume: 62 Pages: 591-597

    • NAID

      120006390866

    • Related Report
      2015 Research-status Report
  • [Journal Article] Analysis of the equine ovarian structure during the first twelve months of life by three-dimensional internal structure microscopy2015

    • Author(s)
      Ono M, Akuzawa H, Nambo Y, Hirano Y, Kimura J, Takemoto S, Nakamura S, Yokota H, Himeno R, Higuchi T, Ohtaki T, Tsumagari S.
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 77 Issue: 12 Pages: 1599-1603

    • DOI

      10.1292/jvms.14-0539

    • NAID

      130005115340

    • ISSN
      0916-7250, 1347-7439
    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] ウマ顆粒膜細胞腫に対するAMH診断基準値の設定とその診断精度2018

    • Author(s)
      村瀬晴崇、Siriwan Tangyuenyong、渡辺元、佐藤文夫、松井朗、羽田哲朗、南保泰雄
    • Organizer
      平成29年度日本獣医師会年次大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 帯広畜産大学馬介在活動室の活動について2017

    • Author(s)
      南保泰雄、齊藤朋子、木田克弥
    • Organizer
      平成28年度日本獣医師会獣医学術学会年次大会
    • Place of Presentation
      石川県立音楽堂(石川・金沢)
    • Year and Date
      2017-02-24
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] 雌馬の生殖機能と疾患 -牛との相違-2017

    • Author(s)
      南保泰雄
    • Organizer
      平成28年度日本獣医師会獣医学術学会年次大会
    • Place of Presentation
      ホテル金沢(石川・金沢)
    • Year and Date
      2017-02-24
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] ウマ顆粒膜細胞腫に対するAMH診断基準値の設定とその診断精度2017

    • Author(s)
      村瀬晴崇、Siriwan Tangyuenyong、渡辺元、佐藤文夫、松井朗、羽田哲朗、南保泰雄
    • Organizer
      へ平成29年度北海道獣医師会北海道地区学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] The intensity of AMH immunostaining in equine cryptorchid testis2017

    • Author(s)
      Nao Komyo, HarutakaMurase, Kayo Habukawa, HisashiShibuya1, Tadashi Yasui, Tadatoshi Ohtaki, Shigehisa Tsumagari and YasuoNambo
    • Organizer
      Fourth World Congress of Reproductive Biology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] モンゴル在来種競走馬の調教中心拍数について2017

    • Author(s)
      羽田 哲朗、Khorolmaa Ch、Nyam-Osor P、Davaakhoo B、南保 泰雄、梅村 孝司
    • Organizer
      第30回日本ウマ科学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 乗用雌馬における血中プロジェステロン濃度の変化2017

    • Author(s)
      野村彬仁、大滝忠利、伊丹泰雪、和智荘平、住吉俊亮、津曲茂久、堀北哲也、南保泰雄
    • Organizer
      第30回日本ウマ科学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 半去勢片側性潜在精巣において抗ミューラー管ホルモン(AMH)の分泌が亢進する病態の免疫組織化学的検索2016

    • Author(s)
      光明南潮、村瀬晴崇、土生川佳世、渋谷久、安井禎、大滝忠利、津曲茂久、南保泰雄
    • Organizer
      第29回日本ウマ科学会学術集会
    • Place of Presentation
      東京大学(文京区・東京)
    • Year and Date
      2016-11-29
    • Related Report
      2016 Research-status Report
  • [Presentation] 馬の子宮内膜炎に対する診断・治療法と牛への応用の可能性2016

    • Author(s)
      南保泰雄
    • Organizer
      第159回日本獣医学会学術集会
    • Place of Presentation
      日本大学(神奈川・藤沢)
    • Year and Date
      2016-09-06
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] 重輓馬における胚胞発育変化の特徴2016

    • Author(s)
      三木 渉、木村優希、南保泰雄、石井三都夫、三宅陽一
    • Organizer
      第159回日本獣医学会学術集会
    • Place of Presentation
      日本大学(神奈川・藤沢)
    • Year and Date
      2016-09-06
    • Related Report
      2016 Research-status Report
  • [Presentation] 馬の顆粒膜細胞腫における抗ミューラー管ホルモン(AMH)およびAMH受容体の局在2016

    • Author(s)
      土生川佳世、村瀬晴崇、木村優希、渡邉謙一、佐々木基樹、南保泰雄
    • Organizer
      第159回日本獣医学会学術集会
    • Place of Presentation
      日本大学(神奈川・藤沢)
    • Year and Date
      2016-09-06
    • Related Report
      2016 Research-status Report
  • [Presentation] サラブレッド雌馬におけるドパミン受容体拮抗剤を用いたプロラクチン分泌2016

    • Author(s)
      村瀬晴崇、佐藤文夫、羽田哲朗、渡辺元、永田俊一、南保泰雄
    • Organizer
      第159回日本獣医学会学術集会
    • Place of Presentation
      日本大学(神奈川・藤沢)
    • Year and Date
      2016-09-06
    • Related Report
      2016 Research-status Report
  • [Presentation] 重輓馬における子宮胎盤厚の月間変動および異常分娩との関連2016

    • Author(s)
      木村優希、羽田真悟、福本奈津子、滄木孝弘、古岡秀文、松井基純、南保泰雄
    • Organizer
      平成28年度北海道獣医師会大会・3学会
    • Place of Presentation
      大雪クリスタルホール(北海道・旭川)
    • Year and Date
      2016-09-01
    • Related Report
      2016 Research-status Report
  • [Presentation] Measuring the combined thickness of uterus and placenta for evaluation of placentitis in Japanese heavy draft mares2016

    • Author(s)
      Kimura Y, Furuoka H, Matsui M, Haneda S, Nambo Y
    • Organizer
      International Congress of Animal Reproduction 2016
    • Place of Presentation
      Tours (France)
    • Year and Date
      2016-06-26
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] The utility of measuring the combined thickness of uterus and placenta for evaluation of placentitis in the Japanese heavy draft horse2016

    • Author(s)
      KIMURAY, FURUOKA H, TAKAHASHI H, MATSUI M, HANEDA S, AOKI T, and NAMBO Y.
    • Organizer
      The 7th Joint Symposium of Veterinary Research among Universities of Veterinary Medicine in East Asia
    • Place of Presentation
      Green World Hotel, Tam Dao National Park, Vietnam
    • Year and Date
      2016-02-21
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] ブルーライトマスクを用いた重輓馬の春季繁殖移行期における早期排卵誘発2016

    • Author(s)
      土生川佳世、木村優希、羽田真悟、松井基純、南保泰雄
    • Organizer
      十勝獣医師会獣医学術研究発表会
    • Place of Presentation
      十勝NOSAI本部(北海道・帯広)
    • Related Report
      2016 Research-status Report
  • [Presentation] 自動エンザイムイムノアッセイ装置による馬の血中プロジェステロン濃度の測定および黄体機能以外のモニターの有用性について2016

    • Author(s)
      南保泰雄、土生川佳世、木村優希、羽田真悟、松井基純
    • Organizer
      十勝獣医師会獣医学術研究発表会
    • Place of Presentation
      十勝NOSAI本部(北海道・帯広)
    • Related Report
      2016 Research-status Report
  • [Presentation] 生産地で応用可能な馬の繁殖性向上技術に関する研究2015

    • Author(s)
      南保泰雄
    • Organizer
      日本ウマ科学会学術集会
    • Place of Presentation
      東京大学(東京・文京区)
    • Year and Date
      2015-11-30
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 妊娠馬における胎盤炎評価のための子宮胎盤厚測定の有用性‐重輓馬の標準値作成について2015

    • Author(s)
      木村優希、滄木孝弘、高橋啓人、羽田真悟、古岡秀文、松井基純、南保泰雄
    • Organizer
      北海道獣医師会・3学会
    • Place of Presentation
      酪農学園大学(北海道・江別市)
    • Year and Date
      2015-09-11
    • Related Report
      2015 Research-status Report
  • [Presentation] サラブレッド妊娠馬の開腹手術が血中プロジェステロンおよびエストラジオール濃度に及ぼす影響2015

    • Author(s)
      佐藤正人、樋口徹、井上哲、後藤忠広、村瀬晴崇、南保泰雄
    • Organizer
      北海道獣医師会・3学会
    • Place of Presentation
      酪農学園大学(北海道・江別市)
    • Year and Date
      2015-09-11
    • Related Report
      2015 Research-status Report
  • [Book] BTCニュース2017

    • Author(s)
      南保泰雄
    • Total Pages
      4
    • Publisher
      軽種馬育成調教センター
    • Related Report
      2016 Research-status Report
  • [Book] 臨床獣医2016

    • Author(s)
      南保泰雄、
    • Total Pages
      2
    • Publisher
      緑書房
    • Related Report
      2016 Research-status Report
  • [Book] 獣医畜産新報2016

    • Author(s)
      南保泰雄
    • Total Pages
      6
    • Publisher
      文永堂
    • Related Report
      2016 Research-status Report
  • [Remarks] 特色ある研究の紹介

    • URL

      http://www.obihiro.ac.jp/focus/focus2.html

    • Related Report
      2017 Annual Research Report 2016 Research-status Report
  • [Remarks] 障がい者乗用馬並びに在来馬の生産法確立事業

    • URL

      http://www.clione.ne.jp/~sample/tikudai-uma/plan.html

    • Related Report
      2017 Annual Research Report
  • [Remarks] 教員一覧

    • URL

      http://www.obihiro.ac.jp/ichiran/nambo_yasuo.html

    • Related Report
      2016 Research-status Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

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