Fundamental research on the treatment and prevention of joint contracture using Low-Intensity Pulsed Ultrasound (LIPUS)

• Project/Area Number: 15K16375
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Nagoya Gakuin University
• Principal Investigator: Watanabe Masanori 名古屋学院大学, リハビリテーション学部, 准教授 (60460549)
• Co-Investigator(Renkei-kenkyūsha): KOJIMA Satoshi 金城大学, 医療健康学部, 准教授 (30454242) ; HOSO Masahiro 金沢大学, 大学院・医薬保健学総合研究科保健学, 教授 (20219182)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000); Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
• Keywords: LIPUS / 関節拘縮 / 関節包 / 病理組織 / 拘縮 / ラット / リハビリテーション

Outline of Final Research Achievements

The effect of Low-Intensity Pulsed Ultrasound (LIPUS) on the treatment and prevention of joint contracture was examined from the histological aspect using experimental animals. LIPUS irradiation improved the narrowing of the spaces between the collagen fiber bundles of the posterior joint capsule caused by immobilization and clarified the possibility that joint contracture is effective for treatment. On the other hand, there was no significant difference in the intervention results aimed at prevention of joint contracture and it was not possible to clarify the usefulness of LIPUS.

Research Products

• [Journal Article] Comparison of the rat models of osteoarthritis for examining the effect of physical therapy (2018)
  • Author(s): 渡邊晶規、小島聖、浅田啓嗣、細正博
  • Journal Title: 名古屋学院大学論集 医学・健康科学・スポーツ科学篇 Volume: 6 Issue: 2 Pages: 1-9
  • DOI: 10.15012/00001081
  • NAID: 120006461326
  • ISSN: 2187-5162
  • URL: https://ngu.repo.nii.ac.jp/records/1094
  • Year and Date: 2018-03-31
  • Peer Reviewed / Open Access
• [Journal Article] マウス変形性膝関節症モデルに対する振動が関節軟骨に及ぼす影響 (2018)
  • Author(s): 小島聖、渡邊晶規、浅田啓嗣、佐々木賢太郎
  • Journal Title: 金城大学紀要 Volume: 18 Pages: 123-129
  • Peer Reviewed
• [Journal Article] Effect of low-intensity pulsed ultrasound therapy on a rat knee joint contracture model (2017)
  • Author(s): Watanabe, M, Kojima, S, Hoso M
  • Journal Title: Journal of Physical Therapy Science Volume: 29 Issue: 9 Pages: 1567-1572
  • DOI: 10.1589/jpts.29.1567
  • NAID: 130006077960
  • ISSN: 0915-5287, 2187-5626
  • Peer Reviewed / Open Access
• [Presentation] Low-Intensity Pulsed Ultrasound（LIPUS） Therapy for Prevention of ROM Limitation and Histopathological Changes in Joint Capsules in the Rat Knee Joint (2017)
  • Author(s): Masanori Watanabe, Satoshi Kojima, Masahiro Hoso
  • Organizer: WCPT-AWP & PTAT Congress 2017
  • Place of Presentation: Bangkok International Trade and Exhibition Centre (Bangkok, Thailand)
  • Year and Date: 2017-06-28
  • Int'l Joint Research
• [Presentation] Low-Intensity Pulsed Ultrasound（LIPUS） Therapy for Prevention of ROM Limitation and Histopathological Changes in Joint Capsules in the Rat Knee Joint (2017)
  • Author(s): Masanori Watanabe, Satoshi Kojima, Masahiro Hoso
  • Organizer: The 7th WPCT - AWP and PTAT Congress 2017
  • Int'l Joint Research
• [Presentation] Effect of Cryotherapy on Model Rats with Osteoarthritis of the Knee (2017)
  • Author(s): Satoshi Kojima, Masanori Watanabe, Keiji Asada, Masahiro Hoso
  • Organizer: The 7th WPCT - AWP and PTAT Congress 2017
  • Int'l Joint Research
• [Presentation] 外傷後の膝関節軟骨損傷の進行に加齢は影響するか？ 半月板不安定モデルを用いた検証 (2017)
  • Author(s): 渡邊晶規、小島聖、浅田啓嗣、細正博
  • Organizer: 第33回 東海北陸理学療法学術大会
• [Presentation] マウス変形性膝関節症モデルにおける自発運動量と組織学的変化の関係 (2017)
  • Author(s): 小島聖、渡邊晶規、浅田啓嗣、細正博
  • Organizer: 第33回 東海北陸理学療法学術大会
• [Presentation] 不動化による膝蓋下脂肪体の萎縮はROM-exで予防できるか ラット膝関節不動化モデルを用いた組織学的検討 (2017)
  • Author(s): 竹田圭佑、竹島英祐、小島聖、渡邊晶規、松﨑太郎、細正博
  • Organizer: 第52回 日本理学療法学術大会
• [Presentation] マウス変形性膝関節症モデルに対する振動刺激が関節軟骨に及ぼす影響 (2017)
  • Author(s): 小島聖、渡邊晶規、浅田啓嗣、細正博
  • Organizer: 第52回 日本理学療法学術大会
• [Presentation] Histopathological Changes in Joint Components in a Rat Knee Joint Contracture Model Following Low-Intensity Pulsed Ultrasound. (2015)
  • Author(s): Masanori Watanabe, Satoshi Kojima, Masahiro Hoso
  • Organizer: World Confederation for Physical Therapy Congress
  • Place of Presentation: Suntec convention &Exhibition Centre (Suntec city, Singapore)
  • Year and Date: 2015-05-01
  • Int'l Joint Research
• [Remarks] 名古屋学院大学研究者情報システム
  • URL: https://www.ngu-kenkyu-db.jp/