| Project/Area Number |
15K17321
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Clinical psychology
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| Research Institution | Kyorin University (2018)
National Center of Neurology and Psychiatry (2015-2017) |
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Principal Investigator |
Oe Yuki 杏林大学, 医学部, 助教 (40722749)
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| Research Collaborator |
Sasaki Yohei
Kikuchi Shino
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| Project Period (FY) |
2015-04-01 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 過敏性腸症候群 / 認知行動療法 / 集団認知行動療法 / 集団療法 |
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| Outline of Final Research Achievements |
We developed a group version of cognitive behavior therapy using interoceptive exposure(group version CBT-IE) for irritable bowel syndrome (IBS) and various materials for treatment. We conducted an open label pilot study in collaboration with Kyoto University and Takatsuki Red Cross Hospital. Seven out of the 12 patients referred were included and completed the intervention. As a result, IBS-QOL, which measures IBS specific quality of life, has an average improvement of 24 points, and IBSSI, which measures the severity of IBS symptoms, has an improvement of 101 points on average. The effect sizes are 3.2(IBS-QOL) and -3.1(IBSSI), respectively. We are currently conducting a randomized controlled trial of group CBT-IE in collaboration with Kyoto University and Takatsuki Red Cross Hospital.
Currently, we are carrying out randomized controlled trials of group version CBT-IE jointly with Kyoto University.
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| Academic Significance and Societal Importance of the Research Achievements |
本研究では、有病率が高く、個人的にも社会的にも負担の大きい疾患である過敏性腸症候群（IBS）に対する集団形式の認知行動療法（CBT）を開発した。CBTは難治性のIBSに対する治療法として各国のガイドラインで推奨されているが、CBTを実施できる専門家の数は十分とはいえず、必要な患者が受けられずにいる状況である。そのため、一人の治療者が同時に複数の患者に対して治療を提供することができる、集団形式によるCBTを開発した。パイロット試験では有望な結果が得られ、現在はより厳密な臨床試験を実施中である。
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