Search for antimicrobial natural products as leads of therapeutic agents for the treatment of ophthalmic infections
| Project/Area Number |
15K18885
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Natural medicines
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| Research Institution | The University of Tokushima |
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Principal Investigator |
Tanaka Naonobu 徳島大学, 大学院生物資源産業学研究部, 准教授 (40455598)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 抗菌活性天然物質 / 植物 / 海洋生物 / 抗菌活性物質 / 天然物質 |
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| Outline of Final Research Achievements |
Searching study for antimicrobial natural products were carried out to develop new leads of therapeutic agents for the treatment of ophthalmic infections. The study resulted in the isolation of new antimicrobial meroterpenes and acylphloroglucinols from Hypericaceous plants and new antimicrobial phenylcoumarins from a Calophyllaceous plant. Hypatulin A isolated from Hypericum patulum is a structurally interesting tricyclic meroterpene possessing antimicrobial activity.
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Report
(3 results)
Research Products
(50 results)
