Influence of Antidiabetic Drug Administration on Bone Implant Contact to Type 2 Diabetic Rats

Research Project

Project/Area Number	15K20451
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Prosthodontics/ Dental materials science and
Research Institution	Kagoshima University
Principal Investigator	HASHIGUCHI Chikoto 鹿児島大学, 医歯学域附属病院, 助教 (10596860)
Project Period (FY)	2015-04-01 – 2018-03-31
Project Status	Completed (Fiscal Year 2017)
Budget Amount *help	¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000) Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000) Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000) Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords	インプラント / 糖尿病 / 歯科インプラント
Outline of Final Research Achievements	Diabetes Mellitus is one of relative contraindications in implant treatment, but in many cases, if blood glucose level is controlled, surgery is performed. However, it is unknown whether the osseointegration has actually been acquired. In this study, we investigate surrounding bone of the implants in the model rat in a state of taking the drug for treating diabetes, and evaluate whether osteogenesis is actually carried out by taking medication for treating diabetes.