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Development of evaluation methods for temporomandibular joint disorder using ultra-fast MRI and fMRI

Research Project

Project/Area Number 15K21103
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Prosthodontics/ Dental materials science and
Biomedical engineering/Biomaterial science and engineering
Research InstitutionKyoto University (2017)
Chubu University (2015-2016)

Principal Investigator

NAKAI RYUSUKE  京都大学, こころの未来研究センター, 研究員 (10576234)

Research Collaborator IWATA HIROO  
TOSHIHIRO TOGAYA  
ABE NOBUHITO  
AZUMA TAKASHI  
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
KeywordsMRI / 生体力学 / FEM / fMRI / DTI / 顎関節 / 顎運動 / functional MRI / 顎関節症 / 応力解析 / 顎関節疾患 / 脳
Outline of Final Research Achievements

The number of patients with temporomandibular joint (TMJ) disorder has increased in recent years. In this study we explored the parameters for accurate imaging of the mandibular motion trajectory using MR dynamic imaging. Moreover, we clarified the relationship between the articular disc displacement and the mechanical condition using finite element method (FEM) analysis and mandibular trajectory data. As a result of functional MRI, brain functional differences between mild TMJ disorder group and control group were revealed.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (15 results)

All 2018 2017 2016 2015

All Journal Article (3 results) (of which Peer Reviewed: 1 results,  Acknowledgement Compliant: 1 results) Presentation (12 results) (of which Int'l Joint Research: 4 results,  Invited: 2 results)

  • [Journal Article] Preparation of an Au-Pt alloy free from artifacts in magnetic resonance imaging2017

    • Author(s)
      Kodama T, Nakai R, Goto K, Shima K, Iwata H
    • Journal Title

      Magn Reson Imaging

      Volume: 44 Pages: 38-45

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 有限要素法応力解析とMRI計測情報を用いた顎関節疾患の力学的要因解析2017

    • Author(s)
      中井隆介、橋本英樹、山口誠二、高玉博朗
    • Journal Title

      中部大学生命健康科学研究所紀要

      Volume: 13 Pages: 77-80

    • NAID

      120006520605

    • Related Report
      2016 Research-status Report
  • [Journal Article] MRIを用いた生体計測評価手法の開発と応用2016

    • Author(s)
      中井隆介、山口誠二、若槻麻里子、東 高志、高玉博朗
    • Journal Title

      中部大学生命健康科学研究所紀要

      Volume: 12 Pages: 65-72

    • NAID

      120006520508

    • Related Report
      2015 Research-status Report
    • Acknowledgement Compliant
  • [Presentation] Analysis of the relationship between mandibular joint motion trajectory and masticatory muscle properties (volume, shape, T1&T2 value) with MR dynamic imaging2018

    • Author(s)
      Nakai R, Azuma T, Togaya T, Iwata H
    • Organizer
      Joint Annual Meeting ISMRM-ESMRMB 2018
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development and evaluation of a single-phase alloy with magnetic susceptibility equivalent to that of mammalian tissue for coil embolization of a cerebral aneurysm2018

    • Author(s)
      Nakai R, Azuma T, Toda M, Kodama T, Iwata H
    • Organizer
      Joint Annual Meeting ISMRM-ESMRMB 2018
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Optimization in biomedical measurement and analysis study of the MR spectroscopy2017

    • Author(s)
      Azuma T, Nakai R
    • Organizer
      CME2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Development of a measurement method for the mandibular movement using MRI2017

    • Author(s)
      Nakai R, Azuma T
    • Organizer
      CME2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] プロトン7T-MRSにおける磁気共鳴周波数のドリフトと生体温度計測2017

    • Author(s)
      東 高志、中井隆介
    • Organizer
      生体医工学シンポジウム2017
    • Related Report
      2017 Annual Research Report
  • [Presentation] Evaluation of the susceptibility artifacts by various materials using MRI2017

    • Author(s)
      Nakai R, Yamaguchi S, Toda M, Azuma T, Hashimoto H, Takadama H
    • Organizer
      第45回日本磁気共鳴医学会大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Analysis of imaging parameters in dynamic imaging of mandibular movement.2016

    • Author(s)
      Nakai R, Azuma T, Wakatsuki M, Hashimoto H, Yamaguchi S, Takadama H
    • Organizer
      第44回日本磁気共鳴医学会大会
    • Place of Presentation
      大宮ソニックシティ(埼玉県大宮市)
    • Year and Date
      2016-09-09
    • Related Report
      2016 Research-status Report
  • [Presentation] 化学及び加熱処理に よりチタン金属表面に 形成されたナノ網目構造の電気的特性2016

    • Author(s)
      橋本英樹、山口誠二、中井隆介、成田吉徳、高玉博朗
    • Organizer
      日本セラミックス協会 第29回秋季シンポジウム
    • Place of Presentation
      広島大学(広島県広島市)
    • Year and Date
      2016-09-07
    • Related Report
      2016 Research-status Report
  • [Presentation] 医用画像の融合による病変部の認識方法の開発2016

    • Author(s)
      中井隆介
    • Organizer
      第8回SLM造形技術の医療応用研究会
    • Place of Presentation
      京都大学(京都府京都市)
    • Related Report
      2016 Research-status Report
  • [Presentation] CT/MRI画像処理による病変部の特定2015

    • Author(s)
      中井隆介
    • Organizer
      第6回SLM造形技術の医療応用研究会
    • Place of Presentation
      京都大学(京都府京都市)
    • Year and Date
      2015-11-25
    • Related Report
      2015 Research-status Report
  • [Presentation] 7T 1H-MR Spectroscopy 法による温度計測に影響を与える磁場ドリフトの測定精度の検討2015

    • Author(s)
      東 高志、栗林秀人、滝沢 修、中井隆介、若槻麻里子、都賀谷紀宏、中村達雄、劉 国相
    • Organizer
      第43回日本磁気共鳴医学会大会
    • Place of Presentation
      東京ドームホテル(東京都文京区)
    • Year and Date
      2015-09-10
    • Related Report
      2015 Research-status Report
  • [Presentation] 生体と同等の磁化率を有する脳動脈瘤塞栓コイル用合金の開発と評価2015

    • Author(s)
      中井隆介、児玉智信、後藤研滋、岩田博夫
    • Organizer
      第43回日本磁気共鳴医学会大会
    • Place of Presentation
      東京ドームホテル(東京都文京区)
    • Year and Date
      2015-09-10
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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