Budget Amount *help |
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2017: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2016: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2015: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
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Outline of Final Research Achievements |
A nixious parasitic plant called Striga hermonthica (Striga) represents a major threat to food security in Africa. In this research project, I focused on a host-depent germination mechanism in Striga and use it to develop a specific herbicide that lead the seeds to "suicide germination". The developed molecule (code name : SAMR690), which is composed of synthetic scaffold connected with the active core structure of strigolactones, exhibits extraordinary potency in stimulating Striga germination at femto-molar range without impinging on beneficial functions in the host strigolactone-related processes. Most importantly, the three-step procedure for synthesizing SAMO-Me-690 greatly increases the potential for Striga eradication via suicide germination campaigns in Africa.
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