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Prediction of pressure ulcer deterioration focused on persistent erythema, and development and evaluation of a new protective skin dressing

Research Project

Project/Area Number 16390637
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Clinical nursing
Research InstitutionThe University of Tokyo

Principal Investigator

SANADA Hiromi  The University of Tokyo, Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授 (50143920)

Co-Investigator(Kenkyū-buntansha) SUGAMA Junko  Kanazawa University, Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授 (00203307)
KONYA Chizuko  Kanazawa University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授 (20303282)
OKUWA Mayumi  Kanazawa University, Graduate School of Medicine, Research Associate, 大学院・医学系研究科, 助手 (30303291)
KITAGAWA Atsuko  The University of Tokyo, Graduate School of Medicine, Research Associate, 大学院・医学系研究科, 助手 (80343185)
Project Period (FY) 2004 – 2006
Project Status Completed (Fiscal Year 2006)
Budget Amount *help
¥14,000,000 (Direct Cost: ¥14,000,000)
Fiscal Year 2006: ¥3,900,000 (Direct Cost: ¥3,900,000)
Fiscal Year 2005: ¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2004: ¥6,500,000 (Direct Cost: ¥6,500,000)
Keywordspressure ulcer / persistent erythema / nursing / elderly / bed-ridden / nursing science and engineering / nursing technology / アセスメント / 転帰 / 予測
Research Abstract

The final study of this project is an evaluation of the effectiveness of a newly-developed dressing for preventing persistent erythema and pressure ulcer development and improving the skin water-holding capacity without increasing the skin pH in bedridden older patients. Shear forces and skin dryness play important roles in persistent erythema and pressure ulcer development. To eliminate these risks, we developed a dressing to reduce shear forces and improve the water-holding capacity. However, the effects of this dressing in clinical settings remain unknown. An experimental bilateral comparison study was conducted at a hospital in Japan in 2004 with 37 bedridden older patients at risk of pressure ulcer development. The dressing was randomly applied to the right or left greater trochanter for three weeks. No dressing was applied to the opposite side as a control. The skin was monitored weekly during the three-week application for persistent erythema and pressure ulcer development. Skin hydration and pH were also assessed during the intervention and for one week after dressing removal. The incidence of persistent erythema was significantly lower in the intervention area than the control area [P=0.007, RR 0.18 (95% C: 0.05-0.73) and NNT 4.11 (2.50-11.63)]. No pressure ulcers occurred in either intervention or control area. Skin hydration increased significantly during dressing application and remained high after removal (P<0.001) relative to the control area. Skin pH decreased significantly during the application (P<0.001) but returned to control levels after removal (P=0.38). This safe and effective dressing can be used for patients with highly prominent bones and dry skin to prevent pressure ulcers.

Report

(4 results)
  • 2006 Annual Research Report   Final Research Report Summary
  • 2005 Annual Research Report
  • 2004 Annual Research Report
  • Research Products

    (10 results)

All 2006 2005

All Journal Article (10 results)

  • [Journal Article] Prognosis of stage I pressure ulcers and related factors.2006

    • Author(s)
      Sato M, Sanada H, Konya C, Sugama J, Nakagami G
    • Journal Title

      Int Wound J. 3・4

      Pages: 355-362

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Incontinence induces stratum corneum vulnerability and impairs the skin barrier function in the perianal region.2006

    • Author(s)
      Nakagami, G., Sanada, H., Kitagawa, A., Tadaka, E., Maekawa, T., Nagase, T., Konya, C.
    • Journal Title

      Dermatology 213・4

      Pages: 293-299

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Comparison of two pressure ulcer preventive dressings for reducing shear force on the heel.2006

    • Author(s)
      Nakagami, G., Sanada, H., Konya, C., Kitagawa, A., Tadaka, E., Tabata, K.
    • Journal Title

      J Wound Ostomy Continence Nurs 33・3

      Pages: 267-272

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Prognosis of stage I pressure ulcers and related factors.2006

    • Author(s)
      Sato M, Sanada H, Konya C, Sugama J, Nakagami G.
    • Journal Title

      Int Wound J. 3(4)

      Pages: 355-362

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Incontinence induces stratum corneum vulnerability and impairs the skin barrier function in the perianal region.2006

    • Author(s)
      Nakagami, G., Sanada, H., Kitagawa, A., Tadaka, E., Maekawa, T., Nagase, T., Konya, C.
    • Journal Title

      Dermatology 213(4)

      Pages: 293-299

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Comparison of two pressure ulcer preventive dressings for reducing shear force on the heel.2006

    • Author(s)
      Nakagami, G., Sanada, H., Konya, C., Kitagawa, A., Tadaka, E., Tabata, K.
    • Journal Title

      Wound Ostomy Continence Nurs 33(3)

      Pages: 267-272

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2006 Final Research Report Summary
  • [Journal Article] Prognosis of stage I pressure ulcers and related factors.2006

    • Author(s)
      Sato M, Sanada H, Konya C, Sugama J, Nakagami G.
    • Journal Title

      Int Wound J. 3・4

      Pages: 355-362

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Incontinence induces stratum corneum vulnerability and impairs the skin barrier function in the perianal region.2006

    • Author(s)
      Nakagami, G., Sanada, H., Kitagawa, A., Tadaka, E., Maekawa, T., Nagase,.T, konya,C.
    • Journal Title

      Dermatology 231・4

      Pages: 293-299

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Comparison of two pressure ulcer preventive dressings for reducing shear force on the heel.2006

    • Author(s)
      Nakagami, G., Sanada, H., Konya, C., Kitagawa, A., Tadaka, E., Tabata,K.
    • Journal Title

      J Wound Ostomy Continence Nurs 33・3

      Pages: 267-272

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 新しい褥瘡予防用保護材の皮膚バリア機能回復効果とずれ力軽減効果に関する研究2005

    • Author(s)
      仲上 豪二朗
    • Journal Title

      日本褥瘡学会誌 7・1

      Pages: 107-114

    • Related Report
      2005 Annual Research Report

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Published: 2004-04-01   Modified: 2021-09-01  

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