Cohort Study on Physical Growth and Development in Triplets and Quadruplets
| Project/Area Number |
16390650
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Community health/Gerontological nurisng
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| Research Institution | Osaka City University (2007)
Okayama University (2004-2006) |
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Principal Investigator |
YOKOYAMA Yoshie Osaka City University, the medical department, Professor (50197688)
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| Co-Investigator(Kenkyū-buntansha) |
大木 秀一 石川県立看護大学, 助教授 (00303404)
森川 善冨 (森川 善富) 産業技術総合研究所, 主任研究官 (60358182)
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| Project Period (FY) |
2004 – 2007
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| Project Status |
Completed (Fiscal Year 2007)
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| Budget Amount *help |
¥10,680,000 (Direct Cost: ¥9,900,000、Indirect Cost: ¥780,000)
Fiscal Year 2007: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2006: ¥2,100,000 (Direct Cost: ¥2,100,000)
Fiscal Year 2005: ¥2,800,000 (Direct Cost: ¥2,800,000)
Fiscal Year 2004: ¥2,400,000 (Direct Cost: ¥2,400,000)
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| Keywords | triplet / twin / singleton / weight / growth / breast-feeding / 身長 / 母乳 / 人工栄養 / 出生頭囲 / 出生順位 / 性別 / 妊娠前のBMI / 多胎児 |
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| Research Abstract |
We analyzed the characteristics of weight growth and present the weight growth charts from birth to six years of age in Japanese triplets. The study included 366 mothers and their 1,098 triplet children, who were born between 1978 and 2006. Data were collected through a mailed questionnaire sent to the mothers asking for information recorded in medical records. Birth weight proved to be the strongest contribution on weight of triplets from one to six years of age. In addition, gestational age was also a significant contributing factor to weight from birth to six years of age. Compared to the 50^<th> percentile of the growth standard for the general population of Japan, the weight deficit of the triplets was more than 40% at birth (male, -1.28kg; female, -1.28kg), decreased within the first one year of age, and fluctuated between 4% and 9% until six years of age (male, -1.82kg; female, -1.78kg). In conclusion, triplets have lower birth weight than singletons and in spite of the rapid catch-up growth during first year of life they are behind singletons even in mid-childhood.
Moreover, we analyzed a database of medical check-up of infants aged 3 to 6 months between April 2001 and July 2004 in Nishinomiya city in Japan. Exclusive breast-feeding was chosen by 6,680 (43.8%) mothers, mixed-feeding by 4,645 (30.4%) mothers, and bottle-feeding with formula milk only by 3,900 (25.6%) mothers. The rate of exclusive breast-feeding among twins or triplets was significantly lower than among singleton babies: 4.1 % among twins or triplets, and 44.7 % among singletons. Twins and triplets were independently associated with a higher rate of bottle-feeding: the odds ratio indicated that mothers who had twins or triplets were 2.44 times more likely to choose bottle-feeding with formula milk only than those who had singletons.
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Report
(5 results)
Research Products
(20 results)
