Control mechanism of pulmonary ventilation in response to exercise in humans
| Project/Area Number |
16500383
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Physical education
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| Research Institution | Prefectural University of Hiroshima (2005-2006)
Hiroshima Prefectural Women's University (2004) |
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Principal Investigator |
FUKUBA Yoshiyuki Prefectural University of Hiroshima, Department of Health Science, Professor, 人間文化学部, 教授 (00165309)
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| Co-Investigator(Kenkyū-buntansha) |
MIURA Akira Prefectural University of Hiroshima, Department of Health Sciences, Prafessor, 人間文化学部, 教授 (30190581)
NISHIYASU Takeshi University of Tsukuba, Institute of Health and Sports Science, Associate Professor, 体育科学系, 助教授 (90237751)
HAYASHI Naoyuki Kyushu University, Institute of Health Science, Associate Professor, 健康科学センター, 助教授 (80273720)
ENDO Masako Prefectural University of Hiroshima, Department of Health Sciences, Research Associate, 人間文化学部, 助手 (30336911)
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| Project Period (FY) |
2004 – 2006
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| Project Status |
Completed (Fiscal Year 2006)
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| Budget Amount *help |
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2006: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 2005: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 2004: ¥1,600,000 (Direct Cost: ¥1,600,000)
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| Keywords | exercise / pulmonary ventilation / physiological control |
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| Research Abstract |
While there are numerous afferent drives to the respiratory center to control exercise ventilation, one of the important drive certainly comes from the exercising skeletal muscles. Stimulation of afferent nerves with endings in hindlimb skeletal muscles is known to have marked reflex effects on the respiratory system of anesthetized animals. The recent animal studies appropriated the neural monitoring system to hemodynamic effect (i.e., a "flow-linked" control) of ventilation. Therefore, to investigated to verify this hypothesis, i.e., whether the mechanosensitive, flow-dependent stimulation in muscle can be linked the ventilatory control in response to exercise in humans, we performed the following experiments, 1; to investigate the effect of occluding of femoral blood flow on the post-exercise ventilatory response of both the sub-and supra-anaerobic threshold (AT) leg cycling, 2; to investigate the effect of static/intermittent compressing stimulus to the lower limb using the anti-shock pant on post-exercise ventilatory response from leg cycling exercise, 3; to investigate the effect of postural change from supine to upright (it means blood retention to the lower limb) just after the cessation of cycling exercise on post-exercise ventilatory response, and 4; to investigate the causal linkage of ventilatory depression and blood flow to the lower limb during cycling exercise just after the 5-minintentional hyperventilation to induce vasoconstriction. As a result, two experiments supported the hypothesis whereas the remaining two did not. Accordingly, further study is clearly needed to deserve these issues.
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Report
(4 results)
Research Products
(11 results)
