| Project/Area Number |
16500397
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Sports science
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| Research Institution | The University of Electro-Communications |
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Principal Investigator |
NAGASAWA Junichi The University of Electro-Communications, Faculty of Electro-Communications, Associate Professor, 電気通信学部, 助教授 (40228002)
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| Co-Investigator(Kenkyū-buntansha) |
IZAWA Tetsuya Tokyo Metroporitan University, Faculty of Health Promotion Science, Professor, 大学院理学研究科, 教授 (70147495)
OHNO Hideki Korin University, Department of Medicine, Professor, 医学部, 教授 (00133819)
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| Project Period (FY) |
2004 – 2006
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| Project Status |
Completed (Fiscal Year 2006)
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| Budget Amount *help |
¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 2006: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2005: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2004: ¥2,100,000 (Direct Cost: ¥2,100,000)
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| Keywords | active oxygen / physical exercise / lactate / 生理学 / 活性酵素 / 運動強度 / 酸化ストレス |
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| Research Abstract |
The purpose of the study was to evaluate the effects of physical exercise to antioxidation power in plasma. Six male subjects (21-25 years old) performed maximal exercise by a gradual increase load using a bicycle ergometer. Exercise load was raised by 25W every four minutes to exhaustion. Blood samples were obtained from the antecubital vein at rest, each load stage, and 10 minutes, 1-hour and 1-day after exercise. As antioxidation power, we measured iron reduction power (Fe^<3+>→Fe^<2+>). The quantity of hydroxyl radical generation was measured by a spin trap method. The lactic acid and the pyruvic acid were measured by an enzyme method. Six another subjects exercised with a physical work as equivalence. The iron reduction power in plasma rose with an increase in exercise intensity. On the contrary, the quantity of generation of a hydroxyl radical decreased with a rise of exercise intensity. This shows that antioxidation power of plasma increases by a rise of exercise intensity. In addition, there were negative relations to lactic acid and ESR signal intensity. These data supported that the plasma lactic acid which increased by exercise has a role of a scavenger of active oxygen.
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