Psychiatric Research on Suicide Attempts: Psychopatholog, Biology, and Risk Factors
| Project/Area Number |
16591152
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Yokohama City University |
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Principal Investigator |
KAWANISHI Chiaki Yokohama City University, Department of Psychiatry, M.D., Ph.D.Associate Professor (50315769)
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| Co-Investigator(Kenkyū-buntansha) |
HIRAYASU Yoshio Yokohama City University, Deparetment of Psychiatry, School of Mdicine, M.D., Ph.D.Professor and Director (70244324)
YAMADA Tomoki Yokohama City University, Deparetment of Psychiatry, School of Mdicine, M.D.Assistant Professor (00315813)
KATO Daiji Yokohama City University, Deparetment of Psychiatry, School of Mdicine, M.D.Assistant Professor (70363819)
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| Project Period (FY) |
2004 – 2007
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| Project Status |
Completed (Fiscal Year 2007)
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| Budget Amount *help |
¥3,540,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2006: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2005: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2004: ¥900,000 (Direct Cost: ¥900,000)
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| Keywords | Suicide / Suicide attempt / Risk factors / Genetic polymorphism / Behavioral Medicine / セロトニン・トランスポーター / セロトニン受容体 / 自殺企画 / 精神疾患 / うつ病 / 統合失調症 |
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| Research Abstract |
The incidence of suicide has increased markedly in Japan since 1998. Since psychological autopsy is not generally accepted in Japan, surveys of suicide attempts, an established risk factor of suicide, are highly regarded. In the present research,564 consecutive suicide attempters who were admitted to an urban emergency department were interviewed with the focus on current and previous suicide attempts, psychosocial background, and psychiatric diagnosis according to DSM-IV. Moreover, impulsivity and aggression were evaluated using standardized scales. Among those attempters 120 attempters and 123 unrelated individuals (healthy controls) were subjected to genetic association studies. Polymerase chain reaction and restriction fragment length polymorphism analyses were performed to determine polymorphisms of the serotonin transporter, 5HTIB, and 14-3-3-ε genes.
The most frequent suicide method was over-dosing, followed by cutting, diving, and hanging. Health problem and human relations were common suicide motives. At least 68 percent of patients met criteria for an axis I disorder. Most frequent diagnosis was mood disorder. Both trait aggression and impulsivity were higher in suicide attempters compared with controls. Regarding genetic background in suicide behavior, G861C of the 5HT1B gene tends to relate to less impulsivity in attempters.
This is the first large-scale study of suicide attempters since the dramatic increase in suicide began in Japan. Information on property of suicide attempters from various viewpoints is necessary when effective measure is developed.
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Report
(5 results)
Research Products
(199 results)
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[Journal Article] Psychiatric assessment of suicide attempters in Japan: a pilot study at a critical emergency unit in an urban area2007
Author(s)
Yamada, T., Kawanishi, C., Hasegawa, H., Sato, R., Konishi, A., Kato, D., Furuno, T., Kishida, I., Odawara, T., Sugiyama, M., Hirayasu, Y
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Journal Title
BMC Psychiatry 7
Pages: 64-64
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Proposals for suicide prevention in general hospitals2007
Author(s)
Kawanishi, C., Iwashita, S., Sugiyama, N., Kawai, M., Minami, Y., Ohmichi, H
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Journal Title
Psychiatry Clin Neurosci 61
Pages: 704-704
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Knowledge and attitude towards suicide among medical students in Japan: a preliminary study2006
Author(s)
Sato, R, Kawanishi, C, PhD, Yamada, T, Hasegawa, H, Nishikawa, H, Kato, D, Furuno, T, Kishida, I, Hirayasu
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Journal Title
Psychiatry Clin Neurosci 60
Pages: 558-562
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Knowledge and attitudes of nurses, nursing students and psychiatric social workers concerning current suicide-related issues in Japan2006
Author(s)
Kawanishi, C., Sato, R., Yamada, T., Ikeda, H., Suda, A., Hirayasu, Y
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Journal Title
Primary Care Mental Health 4
Pages: 285-292
Description
「研究成果報告書概要(欧文)」より
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[Presentation] 自殺対策の基本2008
Author(s)
河西 千秋
Organizer
平成19年地域保健福祉実務研修, 精神保健研修
Place of Presentation
鎌倉
Description
「研究成果報告書概要(和文)」より
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[Presentation] 自殺未遂者のケア2008
Author(s)
河西 千秋
Organizer
平成19年度社会復帰調整官特別研修
Place of Presentation
東京
Description
「研究成果報告書概要(和文)」より
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[Presentation] Drug-overdose in suicide attempters at the emergency department in Japan: relationship to prescribing multiple drugs. 26th Internaitonal Association for Suicide Prevention2007
Author(s)
Yamada T, Nakagawa M, Sato R, Konishi A, Kato D, Odawara T, Arata S, Sugiyama M, Hirayasu Y, Kawanishi C
Organizer
26th Internaitonal Association for Suicide Prevention
Place of Presentation
Killarney,Ireland
Description
「研究成果報告書概要(和文)」より
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[Presentation] 高度救命救急センターにおいて危機介入を実施した自殺未遂者の予後調査(第2報)2007
Author(s)
中川 牧子, 山田 朋樹, 山田 素朋子, 名取 みぎわ, 池田 東香, 須田 顕, 佐藤 玲子, 長谷川 花, 鈴木 範行, 小田原 俊成, 平安 良雄, 河西 千秋
Organizer
日本総合病院精神医学会
Place of Presentation
札幌
Description
「研究成果報告書概要(和文)」より
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[Presentation] Hirayasu Psychiatric assessment of suicide attempters at a critical emergency unit in urban city in Japan2007
Author(s)
Sato, R., Yamada, T., Kawanishi, C., Hasegawa, H., Konishi, A., Kato, D., Furuno, T., Kishida, I., Odawara, T., Sugiyama, M
Organizer
World Psychiatric Association Regional Meeting
Place of Presentation
Seoul
Description
「研究成果報告書概要(欧文)」より
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[Presentation] Drug-overdose in suicide attempters at the emergency department in Japan: relationship to prescribing multiple drugs2007
Author(s)
Yamada, T., Nakagawa, M., Sato, R., Konishi, A., Kato, D., Odawara, T., Arata, S., Sugiyama, M., Hirayasu, Y., Kawanishi, C
Organizer
26th Internaitonal Association for Suicide Prevention
Place of Presentation
Killarney
Description
「研究成果報告書概要(欧文)」より
Related Report
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[Presentation] Systemic screening for CYP2D6 polymorphisms in the patients with neuroleptic malignant syndrome2007
Author(s)
Kato, D., Kawanishi, C., Kishida, I., Furuno, T., Suzuki, K., Onishi, H., Hirayasu , Y
Organizer
20th Congress of the European College of Neuropsychopharmacology(ECNP)
Place of Presentation
Vienna
Description
「研究成果報告書概要(欧文)」より
Related Report
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[Presentation] Drug-overdose in suicide attempters at the emergency department in Japan: relationship to prescribing multiple drugs. 26th Internaitonal Association for Suicide Prevention2007
Author(s)
Yamada T, Nakagawa M, Sato R, Konishi A, Kato D, Odawara T, Arata S, Sugiyama M, Hirayasu Y, Kawanishi C
Organizer
26th Internaitonal Association for Suicide Prevention
Place of Presentation
Killarney, Ireland
Related Report
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[Presentation] 自殺予防を考える2006
Author(s)
河西 千秋
Organizer
秋の市民大学, ルーテル学院大学
Place of Presentation
東京
Description
「研究成果報告書概要(和文)」より
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[Presentation] Knowledge and attitude of psychiatric nurses, medical and nursing students, and psychiatric social workers concerning current suicide-related issues in Japan2006
Author(s)
Kawanishi, C., Yamada, T., Sato, R., Ikeda, H., Hirayasu, Y
Organizer
2nd Asia Pacific Suicide Prevention Conference
Place of Presentation
Singapore
Description
「研究成果報告書概要(欧文)」より
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[Presentation] A Randomized, Controlled,Multicenter Trial of Post-Suicide Attempt Intervention for The Prevention of Further Attempts In JAPAN2006
Author(s)
Kawanishi, C. Hirayasu, Y, Aruga, T, Higuchi, T, Ueda, S, Kanda, S, Fujita, T, Yamada, M, Takahashi, K
Organizer
11th European Symposium on Suicide and Suicidal Behaviour
Place of Presentation
Slovenia
Description
「研究成果報告書概要(欧文)」より
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[Presentation] Suicide Attempts At a Critical Emergency Unit: Comparison between Attempters with/without a2006
Author(s)
Hasegawa, H., Yamada, T., Sato, R., Kato, D., Kishida, I., Furuno, T., Suda, A., Sugiyama, N., Odawara, T., Hirayasu, Y., Kawanishi, C
Organizer
History of Psychiatric Treatment. 11th European Symposium on Suicide and Suicidal Behaviour
Place of Presentation
Slovenia
Description
「研究成果報告書概要(欧文)」より
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[Presentation] Suggestion for safer prescription from the investigation on psychotropic drugs of suicide attempters2006
Author(s)
Kato, D., Kawanishi, C., Yamada, T., Furuno, T., Hasegawa, H., Kishida, I., Sato, R., Hirayasu, Y
Organizer
19th Congress of the European College of Neuropsychopharmacology (ECNP)
Place of Presentation
Paris
Description
「研究成果報告書概要(欧文)」より
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[Presentation] Medical students' knowledge and attitudes toward suicide: the current situation in Japan2005
Author(s)
Sato, R., Kawanishi, C., Yamada, T., Kato, D., Hasegawa, H., Furuno, T., Hirayasu, Y
Organizer
XIII World Psychiatry
Place of Presentation
Cairo
Description
「研究成果報告書概要(欧文)」より
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[Presentation] 自殺の心理学的研究2004
Author(s)
西川 東香, 河西 千秋, 山田 朋樹, 他
Organizer
第144回神奈川県精神医学会
Place of Presentation
横浜
Description
「研究成果報告書概要(和文)」より
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[Book] 刑務官のための手引き2007
Author(s)
河西 千秋(訳・監訳), 平安 良雄(監訳)
Publisher
横浜市立大学精神医学教室刊
Description
「研究成果報告書概要(和文)」より
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[Book] 自殺の実態と援助2006
Author(s)
名取 みぎわ, 河西 千秋
Publisher
中央法規出版
Description
「研究成果報告書概要(和文)」より
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[Book] 老年期精神障害とは2006
Author(s)
名取 みぎわ, 河西 千秋
Publisher
中央法規出版
Description
「研究成果報告書概要(和文)」より
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