Development of simple intraoperative electrophysiological study for chronic atrial fibrillation
| Project/Area Number |
16591399
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Thoracic surgery
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| Research Institution | HIROSHIMA UNIVERSITY |
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Principal Investigator |
IMAI Katsuhiko HIROSHIMA UNIVERSITY, HOSPITAL, ASSISTANT PROFESSOR, 病院, 助手 (80359893)
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| Co-Investigator(Kenkyū-buntansha) |
SUEDA Taijiro HIROSHIMA UNIVERSITY, GRADUATE SCHOOL OF BIOMEDICAL SCIENCES, PROFESSOR, 大学院・医歯薬学総合研究科, 教授 (10162835)
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| Project Period (FY) |
2004 – 2005
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| Project Status |
Completed (Fiscal Year 2005)
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| Budget Amount *help |
¥3,800,000 (Direct Cost: ¥3,800,000)
Fiscal Year 2005: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 2004: ¥3,500,000 (Direct Cost: ¥3,500,000)
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| Keywords | Chronic atrial fibrillation / Intraoperative mapping / Maze procedure / Spectrum analysis / Great veins / Orifice of pulmonary vein / Less invasive procedure / Atrial Potentials |
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| Research Abstract |
Objective : It is not easy to clarify or analyze atrial activation and its propagation pattern during atrial fibrillation (Ar). The aim of this study was to develop a simple mapping system for intraoperative decision-making during surgical Af procedure.
Methods : Atrial electrograms (AEGs) were analyzed in 8 patients with persistent Af, who underwent hybrid procedure associated with other cardiac surgery. The AEGs were acquired with variable circular mapping catheter from the cavo-atrial jubctions. The appearance of dominant peaks (DPs) examined by means of real-time fast Fourier transform (FFT) analysis and the local cycle length estimated from DPs were assessed.
Results : Clustering of DPs were observed in four cases which were collected from left superior pulmonary vein (2 cases), right superior pulmonary vain (1 case) and inferior vena cava (1 case). In two cases with remaining Af postoperatively, the amplitude of AEGs was very low in all mapped portions, so that analysis was not feasible.
Conclusion : By using this new mapping system, the AEGs and DPs could be successfully observed at real time. Further investigations with more clinical data are needed to establish the criteria for intraoperative decision-making.
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Report
(3 results)
Research Products
(15 results)
